Articles tagged "Kidney transplantation"

2018 American Transplant Congress
Peri-Operative Hemoglobin, Blood Transfusion and Delayed Graft Function in Kidney Transplant Recipients
S. MacIsaac, A. Ramankumar, C. Saw, V. Naessens, M. Cantarovich, D. Baran, S. Paraskevas, J. Tchervenkov, P. Chaudhury, S. Sandal.
MUHC, Montreal, Canada.
Background: Studies in the non-kidney transplant (KT) literature support an absolute hemoglobin concentration (Hb) threshold of 70 g/L for transfusion, unless otherwise indicated. Some reports…
2018 American Transplant Congress
Decision-Making, Informed Consent, and the Experiences of Recipients of Experimental HCV Positive-to-Negative Renal Transplants
S. Rasmussen, S. Seaman, D. Brown, N. Desai, M. Sulkowski, D. Segev, J. Sugarman, C. Durand.
JHU, Baltimore.
Background: The safety and efficacy of transplanting HCV-infected (HCV+) donor organs into HCV-uninfected recipients (HCV D+/R-) is being studied. Recipient experiences are essential to comprehensively…
2018 American Transplant Congress
Subclinical Borderline Rejection: More Than Meets the Eye?
M. Bernard, G. Agarwal, H. Fatima, B. Julian, C. Kew, V. Kumar, S. Mehta, S. Ong, A. Patel, G. Towns, M. Seifert, R. Mannon.
UAB School of Medicine, Birmingham.
Purpose: Surveillance biopsies can detect subclinical T cell mediated rejection (SC-TCMR) or subclinical borderline rejection (SC-B-TCMR) in patients with normal/stable creatinine, but the impact on…
2018 American Transplant Congress
Variation in Hypothermic Machine Perfusion Utilization and Clinical Outcomes for Deceased-Donor Kidneys
V. Krishnamoorthy,¹ S. Wunsch,² K. O'Connor,² M. Souter.³
¹Anesthesiology, Duke University, Durham, NC; ²LifeCenter Northwest, Bellevue, WA; ³Anesthesiology and Pain Medicine, University of Washington, Seattle, WA.
Introduction:Hypothermic machine perfusion (HMP) has been shown to be an effective method for preserving kidney allografts from deceased donors (1), but data suggests that low-risk…
2018 American Transplant Congress
Is KDPI Valid for Hepatitis C Aviremic Kidneys?
L. Sibulesky,¹ C. Kling,¹ C. Blosser,² C. Johnson,² A. Limaye,² R. Bakthavatsalam,¹ N. Leca,² J. Perkins.¹
¹Surgery, University of Washington Medical Center, Seattle, WA; ²Medicine, University of Washington Medical Center, Seattle, WA.
KDRI is an estimate of post-transplant kidney graft failure. It is based on ten donor factors that independently affect transplant outcomes, including HCV status from…
2018 American Transplant Congress
Potential Living Donors Identified through Social Media
S. Weeks, K. Kumar, J. Konel, E. King, M. Henderson, A. Cameron, J. Garonzik Wang.
Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD.
Purpose: We previously described a smartphone application that harnesses social media to increase potential living donors among kidney and liver transplant candidates. We compared potential…
2018 American Transplant Congress
Transplanting Kidneys from HCV-Infected Donors into HCV-Negative Recipients: Longer-Term and Extended Results of the THINKER Trial
D. Goldberg,¹ E. Blumberg,¹ P. Abt,¹ M. Levine,¹ P. Porrett,¹ A. Naji,¹ S. Nazarian,¹ D. Sawinski,¹ J. Trofe-Clark,¹ V. Van Deerlin,¹ C. Gentile,¹ J. Smith,¹ M. Kaminski,¹ A. Sicilia,¹ R. Hasz,² L. Suplee,² R. Reddy,¹ R. Bloom,¹ P. Reese.¹
¹University of Pennsylvania, Philadelphia; ²Gift of Life, Philadelphia.
Background: In 2016, 800 kidneys from HCV+ deceased donors were discarded. Short-term (6-month) data from the first 10 subjects in the THINKER-1 trial (NCT02743897; funder:…
2018 American Transplant Congress
Disparity in Access to Kidney Allograft Offers among HIV+ Transplant Candidates
J. Cohen,¹ J. Locke,² B. Shelton,² R. Reed,² P. MacLennan,² D. Sawinski.¹
¹Renal Division, University of Pennsylvania, Philadelphia, PA; ²Comprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham, AL.
Background: Despite having a demonstrated survival benefit with kidney transplantation, patients with chronic viral infections, such as HCV or HIV, face many barriers to transplantation,…
2018 American Transplant Congress
Comparing Outcomes between Induction Immunosuppressive Therapies in Simultaneous Heart/Kidney Transplantation
I. Moinuddin, J. Yu, L. Kang, C. Bhati, D. Bandyopadhyay, A. King, D. Kumar, L. Kamal, D. Tang, I. Yakubu, G. Gupta.
Virginia Commonwealth University, Richmond.
Introduction: There is no published data on the risks and benefits of Induction immunosuppression in simultaneous heart/kidney transplant (SHKT) patients.Methods: We analyzed all SHKT performed…
2018 American Transplant Congress
Inflammation in Scarred Areas (I-IFTA) is a Reflection of Parenchymal Injury (Response to Wounding) Not T Cell-Mediated Rejection
P. Halloran, J. Chang, K. Famulski.
Medicine, University of Alberta, Edmonton, AB, Canada.
Inflammation in fibrotic renal parenchyma (i-IFTA) is associated with decreased graft survival but by Banff rules is not diagnostic for rejection. Some researchers believe that…