ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2018 American Transplant Congress

    Pumping Donor Kidneys Reduces DGF and Improves Allograft Survival without Affecting Rejection Rates

    M. Samoylova, A. Nash, T. Brennan.

    Surgery, Duke University, Durham, NC.

    Recent evidence suggests that hypothermic machine perfusion of donor kidneys reduces delayed graft function (DGF), but data is sparse on its effect on allograft rejection.…
  • 2018 American Transplant Congress

    Urinary Microbiome Associated with Chronic Allograft Dysfunction in Kidney Transplants

    A. Israni,1,2 A. Muthusamy,2 B. Wu,3 B. Guo,3 D. Knights,4 G. Al-Ghalith,4 J. Wu,1 W. Oetting,5 D. Schladt,2 R. Remmel,5 P. Jacobson,5 For DeKAF Genomics & GEN03 Investigators.1

    1Medicine, Hennepin County Medical Center, University of Minnesota (UMN), Minneapolis; 2Minneapolis Medical Research Foundation, Mpls; 3Biostatistics, UMN, Mpls; 4Computer Science, UMN, Mpls; 5College of Pharmacy, UMN, Mpls.

    Background: Microbiome dysbiosis can lead to poor outcomes after kidney transplant (tx) presumably due to immune dysregulation elicited by the microbiome. We hypothesize that chronic…
  • 2018 American Transplant Congress

    The Combination of Area under Curve of Estimated Glomerular Filtration Rate for 2 Years and Annual Rate Change of Estimated Glomerular Filtration Rate Predicts Long-Term Graft Survival in Kidney Transplants

    E. Lee,1 J. Jeon,1 S. Kim,1 M. Kim,1 K. Lee,1 H. Jang,1 J. Lee,1 J. Hwang,2 D. Kim,1 Y-.G. Kim,1 H. Oh,1 W. Huh,1 J. Kim.3

    1Department of Medicine, Samsung Medical Center, Seoul, Republic of Korea; 2Department of Anesthesiology and Pain Medicine, Seoul National University BunDang Hospital, Sungnam, Republic of Korea; 3Department of Surgery, Samsung Medical Center, Seoul, Republic of Korea.

    Improvement of short-term outcomes in kidney transplant (KT) has required clinical trials to evaluate long-term hard outcomes for validation of new therapies. However, because of…
  • 2018 American Transplant Congress

    Elevated Donor Terminal Creatinine Does Not Appear to Be Associated with Worse Outcomes in Kidney Transplantation

    S. Rayhill, J. Haldorson.

    U Washington, Seattly.

    There is justified reluctance to use kidneys from donors with significantly elevated creatinine as they may have severe, irreversible injury. Recently, thanks, in part to…
  • 2018 American Transplant Congress

    Multi-Drug Resistant Urinary Tract Infections Following Renal Transplant: Risk Factors and Patient Outcomes

    D. Hooker,1 K. Gutierrez,2 K. Foster,1 A. Dodson.2

    1Samford University McWhorter School of Pharmacy, Birmingham, AL; 2Comprehensive Transplant Institute, UAB Hospital, Birmingham, AL.

    Background: Urinary tract infections (UTIs) are the most common infection after kidney transplant (KTx) resulting in significant morbidity and mortality. The reported incidence of UTIs…
  • 2018 American Transplant Congress

    Reduced Ratio of FoxP3/ RORγt Gene Expression, in Peripheral Blood, is Associated with Acute Allograft Rejection in Recipients with Kidney Transplantation

    R. Dhital,1,2 R. Minz,3 M. Minz,1,4 A. Sharma,1 R. Nada,5 S. Singh,1 D. Kenwar,1 S. Anand.3

    1Renal Transplant Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, UT, India; 2Vaccines and Immunity, Nationwide Children's Hospital, Columbus, OH; 3Immunopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, UT, India; 4Organ Transplantation, Fortis Hospital, Mohali, Punjab, India; 5Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, UT, India.

    Introduction:FoxP3 has been well established as an indispensable protein that is required in the development and function of regulatory T cells. On the other hand,…
  • 2018 American Transplant Congress

    Identifying Patients with CPRA>99.95% Likely to Be Offered Deceased Donor Kidneys

    R. Parsons, S. Bumb, H. Decker, R. Bray, H. Gebel.

    Emory Transplant Center, Atlanta, GA.

    The implementation of the new kidney allocation system and priority of kidneys for cPRA=100% subjects revealed a hierarchy difference in allocation to patients with cPRA=99.45%-100%.…
  • 2018 American Transplant Congress

    Transplant Hospitals Increase Volumes and Acceptance Rates under the COIIN Project

    D. Klassen, H. Haskell, K. Sisaithong, M. McBride, R. Carrico, M. Curry.

    United Network for Organ Sharing, Richmond.

    Introduction. Transplant center performance monitoring is based on one-year patient and graft survival. Through the OPTN contract with HRSA, UNOS created the Collaborative Innovation and…
  • 2018 American Transplant Congress

    Impacts of HBsAg Seropositive Status on Patient and Graft Survival after Kidney Transplantation in the Era of New Antiviral Therapy: A Meta-Analysis

    N. Leeaphorn,1 C. Thongprayoon,2 K. Sharma,2 A. Sakhuja,3 W. Cheungpasitporn.4

    1Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA; 2Department of Medicine, Bassett Medical Center, Cooperstown, NY; 3Department of Medicine, Mayo Clinic, Rochester, MN; 4Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson, MS.

    BACKGROUND: An association between HBsAg seropositive status and increased mortality after kidney transplantation has been demonstrated in previous studies over the past decade. Although chronic…
  • 2018 American Transplant Congress

    Thirty-Six Consecutive Kidney Transplants in Recipients with Atypical Hemolytic Uremic Syndrome: A Single-Centre Experience

    E. Favi,1 G. Ardissino,2 D. Cresseri,3 J. Brocca,1 S. Testa,4 F. Tel,4 A. Giussani,1 C. Colico,1 C. Beretta,1 M. Ferraresso.1

    1Kidney Transplantation, Fondazione IRCCS Ca' Granda, Milan, Italy; 2Centre for HUS Prevention, Control and Management, Fondazione IRCCS Ca' Granda, Milan, Italy; 3Nephrology, Fondazione IRCCS Ca' Granda, Milan, Italy; 4Pediatric Nephrology, Fondazione IRCCS Ca' Granda, Milan, Italy.

    Background. Due to high recurrence rate, poor kidney transplant (KTx) survival has been reported for recipients with atypical hemolytic uremic syndrome (aHUS). More recently, prophylaxis…
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