2018 American Transplant Congress
Non-Myeloablative Conditioning with Low-Dose Total Body Irradiation in Place of Cyclophosphamide Induces Mixed Chimerism and Long-Term Immunosuppression Free Allograft Survival without Acute Kidney Injury in HLA Mismatched Kidney Transplantation
We have achieved successful induction of long-term immunosuppression (IS) free renal allograft survival in HLA mismatched kidney transplantation using cyclophosphamide (CP) based conditioning and combined…2018 American Transplant Congress
Elucidating Novel Signatures of Allograft Rejection through Cytometry by Time of Flight (CyTOF) in Kidney Transplant Recipients
Mass cytometry by time-of-flight (CyTOF) permits the simultaneous assessment of over 40 functional and phenotypic parameters at the single-cell level. This novel tool holds tremendous…2018 American Transplant Congress
Influence of X-Ray Repair Cross-Complementing Group (XRCC) Genes Polymorphisms on the Development of Antibody-Mediated Rejection (ABMR) in Renal Transplant Recipients
The importance of antibody-mediated rejection (ABMR) on the renal transplant recipients has been recognized in recent years. However, the pathogenesis of ABMR following kidney transplantation…2018 American Transplant Congress
The Impact of Pre-Transplant Donor Specific Antibodies (DSA) on AMR Rates in HIV-Infected Kidney Transplant Recipients Inducted with IL-2 RA
Recanati Miller Transplant Institute, Icahn School of Medicine at Mt. Sinai, New York, NY.
Background: 1-year rejection rates in HIV-infected kidney transplant recipients range from 15-40%, compared to overall rejection rates of 10% in HIV-negative patients. We report the…2018 American Transplant Congress
Risk Factors for Graft Failure in Kidney Transplant Recipients with Polycystic Kidney Disease
University of Wisconsin, Madison.
Background: Polycystic kidney disease (PKD) is the underlying renal disease in 15% of kidney transplant recipients (KTRs) in the US. Post-transplant outcomes and contributing factors…2018 American Transplant Congress
Unique Recipient Benefits with Paired Kidney Donation
Introduction: Kidney transplantation is the treatment choice for ESRD with improved survival and cost benefit compared with dialysis. The imbalance of supply over demand along…2018 American Transplant Congress
Evaluation of Allergy to Tacrolimus in Kidney Transplant Candidates and Recipients with a History of Macrolide Antibiotic Allergy
Background: Tacrolimus (TAC) is considered a drug of choice for maintenance immunosuppression among kidney transplant (KTX) recipients. Because of structural resemblances between macrolide antibiotics (azithromycin,…2018 American Transplant Congress
Metabolic Complications 10-Years after Kidney Transplant
Background: Improving long-term outcomes is an important but unmet need after kidney transplant. Protocol renal allograft biopsies taken 10-years after transplant frequently show diabetic nephropathy…2018 American Transplant Congress
Measures of Physical Frailty, Cardiac Function and Cardiac Biomarkers among Kidney Transplant Candidates
1Intermountain Medical Center, Murray, UT; 2University of Utah, Salt Lake City, UT.
Background: Elevated troponin T at transplant evaluation has been reported to confer risk of cardiovascular mortality among renal transplants. We use troponin T along with…2018 American Transplant Congress
Predictors of Early Graft Loss in Older Kidney Transplant Recipients
Medical University of South Carolina, Charleston, SC.
Older kidney transplant recipients are vulnerable to early graft loss likely due to frailty and burden of comorbidities. Other factors not inherent to the recipient…
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