Articles tagged "Kidney transplantation"

2018 American Transplant Congress
Impact of Cigarette Smoking on Living Kidney Donor
Y. Yoon,¹ H. Lee,² J. Na,³ K. Huh,⁴ M. Kim,⁴ S. Kim,⁴ Y. Kim,⁴ W. Han.³
¹Urology, Hanyang University College of Medicine, Seoul, Korea; ²Urology, National Health Insurance Service Ilsan Hospital, Goyang, Korea; ³Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Korea; ⁴Transplantation Surgery, Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea.
Introduction: Smoking is known to result in the decline of renal allograft function and survival of recipients. However, effect of smoking on living kidney donor…
2018 American Transplant Congress
Laparoscopic Donor Nephrectomy Safety: Experience of 500 Cases in Hispanic Population at a Single Institution
Y. Baez Suarez, F. Giron Luque, J. Amaya Nieto.
Transplantation Surgery, Colombiana de Trasplantes, Bogota, Colombia.
Background: Laparoscopic live donor nephrectomy (LDN) has become the best option in living donation because its safety and low rate of complications. This report aims…
2018 American Transplant Congress
Donor-Derived Cell-Free DNA Identifies Antibody-Mediated Rejection with Graft Injury in DSA-Positive Kidney Transplant Recipients
S. Jordan,¹ S. Bunnapradist,² J. Bromberg,³ A. Langone,⁴ D. Hiller,⁵ J. Yee,⁵ J. Sninsky,⁵ R. Woodward,⁵ A. Matas.⁶
¹Cedars-Sinai Medical Center, Los Angeles, CA; ²UCLA, Los Angeles, CA; ³University of Maryland School of Medicine, Baltimore, MD; ⁴Vanerbilt University Medical Center, Nashville, TN; ⁵CareDx, Brisbane, CA; ⁶University of Minnesota School of Medicine, Minneapolis, MN.
Purpose: Donor-derived cell-free DNA (dd-cfDNA) discriminates active rejection in kidney transplant patients. Donor-specific antibodies (DSA) to HLA antigens are associated with risk of antibody-mediated rejection…
2018 American Transplant Congress
Mortality and Kidney Transplantation Outcomes among Chronic Dialysis Patients Who Are Seropositive for Hepatitis C Virus
D. Sawinski,¹ F. Kimberly,¹ L. Vincent,¹ S. Justine,¹ B. Colleen,¹ C. Jordana,¹ G. David,¹ L. Jayme,² W. Joe,³ R. Peter.¹
¹Univ of Pennsylvania, Philadelphia, PA; ²Univ of Alabama, Birmingham, AL; ³DaVita, Minneapolis, MN.
Hepatitis C virus (HCV) infection is common among patients receiving chronic dialysis. However, few studies have examined both survival on dialysis as well as transplantation…
2018 American Transplant Congress
Recurrence of Immunoglobulin A Nephropathy in Related Donor Kidney Transplant Recipients
M. Okumi,¹ D. Okada,¹ K. Unagami,² Y. Kakuta,¹ H. Shirakawa,³ T. Shimizu,⁴ K. Omoto,⁴ H. Ishida,¹ K. Tanabe.¹
¹Urology, Toyko Women's Medical University, Tokyo, Japan; ²Nephrology, Toyko Women's Medical University, Tokyo, Japan; ³Urology, Ohkubo Hospital, Tokyo, Japan; ⁴Urology, Toda Chuo General Hospital, Saitama, Japan.
BackgroundSecondary to an increase in the graft survival rates in patients undergoing successful kidney transplantation, an increase in the occurrence of recurrent glomerulonephritis has been…
2018 American Transplant Congress
Outcome Implications of Benzodiazepines and Opioid Co-Prescriptions before Kidney Transplantation
N. Lam,¹ M. Schnitzler,² D. Axelrod,³ V. Dharnidharka,⁴ D. Segev,⁵ A. Naik,⁶ H. Xiao,² R. Ouseph,² H. Randall,² G. Hess,⁷ B. Kasiske,⁸ D. Brennan,⁵ T. Alhamad,⁴ K. Lentine.²
¹Univ Alberta, Edmonton, Canada; ²Saint Louis Univ, St. Louis; ³Lahey Clinic, Burlington; ⁴Washington Univ, St. Louis; ⁵Johns Hopkins, Baltimore; ⁶Univ Michigan, Ann Arbor; ⁷Hennepin, Minneapolis; ⁸Symphony Health, Conshohocken.
Recent studies have identified co-prescription of benzodiazepines and opioids as a risk factor for adverse outcomes in the general population. We previously described associations of…
2018 American Transplant Congress
Worsening Racial/Ethnic Disparities in Pediatric Kidney Transplant Outcomes in the US
T. Purnell, X. Luo, L. Cooper, D. Crews, K. Covarrubias, A. Massie, D. Segev.
Johns Hopkins, Baltimore.
Purpose: We recently demonstrated narrowed racial/ethnic disparities in adult kidney transplant (KT) outcomes in the US. The goal of this study was to examine twenty-year…
2018 American Transplant Congress
Prolonged Cold Ischemia Storage of Renal Allografts Shifts DSA Specificity and Enchances Glomerular Injury
V. Gorbacheva, R. Fan, W. Baldwin, A. Valujskikh.
Immunology, Cleveland Clinic, Cleveland, OH.
Prolonged cold ischemia storage (CIS) of donor organs is a major risk factor for acute and chronic graft injury. The goal of this study was…
2018 American Transplant Congress
Relationship between Living Kidney Donor Follow-Up GFR and Recipient Graft Loss
C. Holscher,¹ T. Ishaque,¹ C. Haugen,¹ S. DiBrito,¹ K. Jackson,¹ A. Muzaale,¹ A. Massie,^1,2 M. Henderson,¹ J. Garonzik Wang,¹ D. Segev.^1,2,3
¹Johns Hopkins School of Medicine, Baltimore; ²Johns Hopkins School of Public Health, Baltimore; ³Scientific Registry of Transplant Recipients, Minneapolis.
In living kidney transplantation, it is reasonable to believe a donated kidney's function would be associated with the function of the donor's remaining kidney. Indeed,…
2018 American Transplant Congress
Survey of Rabbit Anti-Thymocyte Globulin Usage for Kidney Transplant Induction Therapy in the United States
K. Foster,¹ A. Dodson,² K. Gutierrez.²
¹Samford University McWhorter School of Pharmacy, Birmingham, AL; ²Comprehensive Transplant Institute, UAB Hospital, Birmingham, AL.
Background: Rabbit anti-thymocyte globulin (rATG) has become the most widely used induction agent in kidney transplantation (KTx) and has recently received FDA approval for this…