ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2022 American Transplant Congress

    Evaluation of Technical Bladder Complications in Kidney Transplantation Recipients with a Prolonged Dialysis History

    S. M. Zielsdorf, K. Kushwaha, C. Goldbeck, S. Martin, Y. Kwon, K. Etesami, J. Kim, J. Emamaullee, S. Zielsdorf

    University of Southern California, Los Angeles, CA

    *Purpose: The kidney transplant (KT) waiting list continues to expand, resulting in prolonged dialysis times of >8 years prior to transplantation in some regions. The…
  • 2022 American Transplant Congress

    Bystander Suppression: Enhancing the Power of Ex Vivo Expanded Antigen Specific Regulatory Cell Lines

    S. Tripathi1, P. L. Martin-Moreno2, G. J. Kavalam3, B. Schreiber3, A. Wagaa-Gasser1, A. Chandraker4

    1Renal, Brigham and Women's Hospital, Boston, MA, 2Nephrology, Clinica Universidad de Navarra, Ripagaina, Spain, 3Brigham and Women's Hospital, Boston, MA, 4Medicine, Brigham and Women's Hospital, Boston, MA

    *Purpose: The potential of T regulatory cell (Treg) based therapies in transplantation has been demonstrated in various preclinical models. Multiple clinical trials are currently undergoing…
  • 2022 American Transplant Congress

    Circulating and Intragraft Donor (HLA)-Specific B Cells Drive Allograft Rejection After Kidney Transplantation

    A. Torija1, N. Bolaños1, L. Donadeu1, M. Meneghini2, I. Torres2, A. Gabaldon2, M. Gomà3, E. Crespo1, F. Moreso4, O. Bestard2

    1Vall d'Hebron Research Institute (VHIR), Barcelona, Spain, 2Vall d'Hebron University Hospital, Barcelona, Spain, 3Bellvitge University Hospital, Barcelona, Spain, 4Vall d'Heron University Hospital, Barcelona, Spain

    *Purpose: Besides donor-specific antibodies (DSA), circulating donor(HLA)-specific memory B cells (mBc) have also shown to play a deleterious role driving antibody-mediated rejection (ABMR) in kidney…
  • 2022 American Transplant Congress

    Pre-Transplant Desensitization Utilizing Intravenous Immune-Globulin and Tocilizumab: A Single Center Experience

    I. Moinuddin, M. Miles, S. Sterling, A. Brown, P. Kimball, G. Gupta

    Virginia Commonwealth University Health System, Richmond, VA

    *Purpose: Highly sensitized end stage kidney disease patients face a huge barrier to transplant due to lack of effective pre-transplant desensitization therapies. Various strategies have…
  • 2022 American Transplant Congress

    Clinical Validation of Automated Urinary Chemokine Assays for Non-Invasive Detection of Kidney Transplant Rejection: A Large Prospective Cohort Study

    E. Van Loon1, C. Tinel1, J. Callemeyn1, M. Coemans1, A. Van Craenenbroeck1, T. Vaulet2, D. Anglicheau3, M. Naesens1

    1Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, 2ESAT STADIUS Center for Dynamical Systems, KU Leuven, Leuven, Belgium, 3Department of Nephrology and Kidney Transplantation, Necker Hospital, Paris, France

    *Purpose: Non-invasive diagnostic markers for kidney transplant rejection can provide useful information but often do not reach the clinical implementation stage. The chemokines CXCL9 and…
  • 2022 American Transplant Congress

    Moving Beyond the Waitlist in Measurement of Access in Kidney Transplantation

    L. C. McMichael, D. T. Chang, M. Kadatz, J. Gill

    University of British Columbia, Vancouver, BC, Canada

    *Purpose: Studies limited to waitlist candidates have suggested better access to kidney transplantation and fewer disparities in acesss since the new kidney allocation system (KAS)…
  • 2022 American Transplant Congress

    Longitudinal Characterization of the Microvirome in a Cohort of Renal Transplant Recipients

    A. C. Johnson, G. Karadkhele, C. P. Larsen

    Emory University, Atlanta, GA

    *Purpose: The selective targeting of T cells in transplant immunosuppression medications leads to a high rate of viral infections, with different immunosuppression regimens resulting in…
  • 2022 American Transplant Congress

    Conversion to Everolimus-Based Immunosuppression Regimen with Calcineurin Inhibitor Reduction Ameliorates Histological Damage in Kidney Transplant Recipients with Calcineurin Inhibitor-Induced Nephrotoxicity

    K. Hotta, N. Iwahara, T. Tanabe, N. Shinohara

    Hokkaido University Hospital, Sapporo, Japan

    *Purpose: In the last two decades, the short-term results for kidney transplantation (KTX) have improved owing to the use of calcineurin inhibitors (CNIs). However, long-term…
  • 2022 American Transplant Congress

    Cold Pulsatile Perfusion Preservation of Deceased Donor Kidneys Did Not Improve Delayed Graft Function Rates in Most Transplants Due to Longer Cold Ischemia Times Offsetting Much of the Benefit, Analysis of SRTR Database

    D. S. Keith, E. Lessmann

    Kidney Transplant, Ascension Sacred Heart Hospital, Pensacola, FL

    *Purpose: To determine the impact of cold pulsatile perfusion preservation (CPPP) on delayed graft function (DGF) in a national cohort of US kidney transplants as…
  • 2022 American Transplant Congress

    Prediction of Delayed Graft Function After Deceased Donor Kidney Transplantation Using Machine Learning and Sequential Donor Data

    J. Sageshima1, J. Yu1, H. Lala Gul1, F. De Leon1, N. Goussous1, N. Mineyev1, P. Than1, K. Jen2, R. Perez1

    1Surgery, University of California Davis Health, Sacramento, CA, 2Pathology, University of California Davis Health, Sacramento, CA

    *Purpose: Delayed graft function (DGF) has been associated with adverse kidney transplant outcomes. Accurate prediction of DGF before surgery will help select organs and candidates…
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