ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2018 American Transplant Congress

    A Research-Informed Framework for a Medication Adherence Intervention to Support Transition of Adolescent Kidney Recipients to Independent Medication-Taking

    T. Irizarry,1 A. DeVito Dabbs,1 M. Dew,1 B. Foster.2

    1University of Pittsburgh, Pittsburgh, PA; 2MUHC, McGill, Montreal, QC, Canada.

    Purpose: Understand the needs and preferences of adolescent/young adult kidney recipients (12-24y), parents, and healthcare professionals (HCP), to inform adaptation of an efficacious adherence-promoting intervention…
  • 2018 American Transplant Congress

    Frailty and Kidney Transplantation: AST-KPCOP Survey of Center Practices

    M. McAdams DeMarco, S. Rasmussen, R. Parsons, T. Alhamad, K. Johansen, S. Tullius, R. Lynch, M. Harhay, M. Rao, J. Berger, J. Lappin, J. Tan, X. Cheng, K. Woodside, S. Parajuli, K. Lentine, B. Kaplan, D. Segev, J. Kobashigawa, D. Dadhania.

    Kidney Pancreas COP, AST, Mt. Laurel.

    Background: Frailty is a clinical phenotype of decreased physiologic reserve and resistance to stressors. Given the potential utility of frailty evaluation as prognosticator of kidney…
  • 2018 American Transplant Congress

    Urinary Proteomic Biomarkers for Prediction of Chronic Antibody-Mediated Rejection in Kidney Transplant Recipients

    H. Jung,1 K. Jeong,1 J-.H. Lim,1 J. Choi,1 J-.H. Cho,1 S-.H. Park,1 Y-.L. Kim,1 C-.H. Lee,2 M-.C. Baek,2 B. Chung,3 S-.H. Lee,4 C-.D. Kim.1

    1Internal Medicine, Kyungpook National University School of Medicine, Daegu, Republic of Korea; 2Molecular Medicine, Kyungpook National University School of Medicine, Daegu, Republic of Korea; 3Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea; 4Internal Medicine, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.

    Background: Chronic antibody-mediated rejection (CAMR) is a challenging issue associated with allograft loss in kidney transplant recipients (KTRs) undergoing long-term follow-up. Changes in the urinary…
  • 2018 American Transplant Congress

    Machine Learning to Assess Kidney Donor Risk

    A. Shah, M. Li, Z. Chen.

    Thomas Jefferson University, Philadelphia, PA.

    Organ quality estimation is critical in allocation and organ acceptance in renal transplantation. Standard methods determine the likelihood of an outcome of interest utilizing Cox…
  • 2018 American Transplant Congress

    Identification of Novel Genetic Variants Associated with Tacrolimus Metabolism in Kidney Transplant Recipients Using Next Generation Sequencing

    C. Dorr,1,2,3 B. Wu,2 R. Remmel,2 A. Muthusamy,1 D. Schladt,1 J. Abrahante,2 W. Guan,2 R. Mannon,4 A. Matas,2 W. Oetting,2 P. Jacobson,2 A. Israni.1,2,3

    1Minneapolis Medical Research Foundation, Minneapolis; 2Univ. of MN, Minneapolis; 3Hennepin County Medical Center, Minneapolis; 4Univ. of AL, Birmingham.

    Tacrolimus (Tac) pharmacogenomics studies have identified common genetic variants that alter Tac troughs and developed specific dosing strategies for specific populations. Known common variants and…
  • 2018 American Transplant Congress

    Presence of Chronic Vascular Lesions on Allograft Biopsy is Associated with Greater Improvement in Renal Function after Conversion from Tacrolimus to Belatacept

    M. Perez-Saez,1,2 B. Yu,1 A. Uffing,1 N. Murakami,1 J. Azzi,1 S. El Haji,3 S. Gabardi,3 L. Riella.1

    1Transplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; 2Servicio de Nefrologia, Hospital del Mar, Barcelona, Spain; 3Pharmacy Services, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

    Background: Conversion from tacrolimus to belatacept has been shown to be beneficial for an increasing number of kidney transplant (KT) patients. However, predicting factors for…
  • 2018 American Transplant Congress

    Prolonged-Release Tacrolimus Dosing in De Novo Kidney Transplantation: Randomized, Open-Label, Pilot Study

    Y. Kim,1 Y. Chiang,2 S. Kim,3 M. Kim,4 S. Park,5 S. Wu,6 K. Horita,7 Y. Nakashima,7 H. Jiang,8 D. Han.1

    1Asan Medical Center, Seoul, Korea; 2Chang Gung Memorial Hospital-Linkou, Taoyuan City, Taiwan; 3Samsung Medical Center, Seoul, Korea; 4Severance Hospital, Seoul, Korea; 5Dongsan Medical Center, Daegu, Korea; 6Tri-Service General Hospital, Taipei City, Taiwan; 7Astellas Pharma, Inc., Tokyo, Japan; 8Astellas Pharma, Inc., Maao, Singapore.

    A multicenter, randomized, open-label, parallel-group, pilot, 52-wk study in Asian countries that assessed renal function, efficacy, and safety of low vs standard-dose prolonged-release tacrolimus (PRT)…
  • 2018 American Transplant Congress

    Outcomes in Living Kidney Transplant Donor and Recipient Operations with Same vs. Different Surgeons

    J. Sokolich,1 J. Buggs,1 D. Mahon,2 E. Rogers,3 V. Bowers.1

    1Transplant Surgery, Tampa General Medical Group, Tampa General Hospital, Tampa, FL; 2Pre-Med Undergraduate, University of South Florida, Tampa, FL; 3Transplant Research, Tampa General Hospital, Tampa, FL.

    Introduction: Living Kidney Transplantation (LKT) has provided a means of increasing the organ pool for patients with end-stage renal disease (ESRD). Surgical practices vary regarding…
  • 2018 American Transplant Congress

    Impact of an Anastomosis Time on Transplant Outcomes in Deceased Donor Kidney Transplantation

    K. Jeong, H. Jung, J. Choi, J-.H. Lim, J. Choi, J-.H. Cho, S-.H. Park, Y-.L. Kim, C-.D. Kim.

    Internal Medicine, Kyungpook National University School of Medicine, Daegu, Republic of Korea.

    Background: It is known that the increase in anastomosis time (AT) in deceased donor kidney transplantation (DDKT) is associated with increased incidence of delayed graft…
  • 2018 American Transplant Congress

    Role of BK Virus-Specific T Cell Immune Monitoring for BK Virus-Associated Nephropathy in Kidney Transplant Recipients

    J. Bruminhent,1 S. Srisala,2 C. Klinmalai,3 S. Pinsai,1 S. Watcharananan,1 S. Kantachuvessiri,5 S. Hongeng,4 N. Apiwattanakul.3

    1Division of Infectious Diseases, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 2Research Center, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 3Division of Infectious Diseases, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 4Division of Hematology and Oncology, Department of Pediatrics Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 5Division of Nephrology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

    Background: Reduced immunosuppression in a key therapy for BK virus (BKV)-associated nephropathy (BKVAN) in kidney transplant (KT) recipients. A study of immune monitoring against BKV…
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