2018 American Transplant Congress
A Low Level of De Novo DSA Sialylation is Associated with a Decreased of Allograft Survival in Non-Sensitized Kidney Transplant Recipients
Background. In kidney transplantation, de novo donor specific antibodies (dnDSA) are associated with antibody-mediated rejection (ABMR) and graft failure. While appearance of dnDSA, there is…2018 American Transplant Congress
Cost Impacts of Alternative Kidney Transplant Immunosuppression: A National Cohort Study
Economic outcomes are increasingly considered along with clinical efficacy to guide choice of alternative therapies. We examined the cost impact of kidney transplant (KTx) induction…2018 American Transplant Congress
Longitudinal Molecular Assessment of Renal Allograft and Short-Term Outcome: Markers of Injury and Recovery
1Surgery, UVA, Charlottesville; 2NWU, Chicago.
Background: Ischemia reperfusion (I/R) is influenced by both donor and recipient characteristics and affects early graft function and the recovery process. To understand underlying mechanisms…2018 American Transplant Congress
DNA Methylation Age and Differential Patterns of DNA Methylation in Older Compared with Younger Kidney Transplant Recipients
David Geffen School of Medicine at UCLA, Los Angeles, CA.
Introduction: Older transplant recipients experience increased rates of infection and death, but decreased rates of rejection, suggesting a role of immune dysfunction. Analysis of DNA…2018 American Transplant Congress
Title: Donor-Derived Cell Free DNA Predicts Development of Clinically Significant Changes in Donor Specific Antibody Following Kidney Transplant
Background: Recently, high immunologic risk patients comprise a significant percentage of the total adult renal transplants performed yearly. Surveillance management of these patients and interpretation…2018 American Transplant Congress
Interstitial Inflammation is Correlated with DQ Antibodies in Kidney Transplant Recipients
Icahn School of Medicine at Mount Sinai, New York.
Background: Studies have shown that borderline rejection (BR) and acute cellular rejection (ACR) often co-occur with antibody-mediated rejection (AMR). We examined the association between interstitial…2018 American Transplant Congress
Elevated Levels of CD19+ B Cells before or after Rituximab Administration is a Risk Factor for the Early Rejection of a Living Kidney Transplant
1Nephrology, Ohkubo Hospital, Tokyo, Japan; 2Urology, Ohkubo Hospital, Tokyo, Japan.
[Introduction]Rituximab (RTX) is used for desensitization in highly sensitized patients, such as those undergoing ABO-incompatible (ABOi) kidney transplantation. Although RTX is generally effective, some patients…2018 American Transplant Congress
Standard- versus Low-Dose Valganciclovir for Cytomegalovirus Prophylaxis in Intermediate-Risk Kidney Transplant Recipients
Henry Ford Hospital, Detroit, MI.
Background: Although guidelines recommend valganciclovir (VGC) 900 mg daily for cytomegalovirus (CMV) prophylaxis in solid organ transplant patients, multiple centers have reported clinical success, reduced…2018 American Transplant Congress
Clinical Outcomes of Kidney Transplant Recipients Infected with Hepatitis C Virus and Treated with Direct-Acting Antiviral Therapy
Introduction:Hepatitis C virus (HCV) infection has negative impact on patient and graft survival in kidney transplant recipients. In the past, treatment of HCV infection post…2018 American Transplant Congress
High Serum Resistin Levels Predict Future Acute Kidney Injury in Kidney Transplantation Patients
Introduction:Resistin has a pathogenic role in the development and progression of atherosclerosis. This study was evaluated the association between serum resistin levels and future acute…
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