Articles tagged "Kidney transplantation"

2018 American Transplant Congress
Reassessment of Virtual Crossmatch: The Clinical Meaning of Cell-Based Actual Crossmatch for Kidney Transplantation
B. Peng,^1,2 M. Yu,^1,2 Q. Zhuang,^1,2 H. Liu,^1,2 L. Zhu,^1,2 Y. Liu,^1,2 K. Cheng,^1,2 Y. Ming.^1,2
¹Transplantation Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China; ²Engineering & Technology Research Center for Transplantation Medicine, National Ministry of Health, Changsha, Hunan, China.
Background: Due to the high sensitivity and specificity of Luminex technique, the Luminex single antigen beads (LSAB) assays are widely used in detecting the HLA…
2018 American Transplant Congress
Successful Transplantation of Black Kidneys from Rhabdomyolysis Donors
X-.P. Yuan,¹ C-.B. CHen,¹ Y. Zheng,¹ X. Gu,² Q. Zu,³ C. Wang,¹ X. He.¹
¹Organ Transplant Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; ²Department of Urology, First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, China; ³Department of Urology, Chinese PLA General Hospital, Beijing, China.
Background: The kidneys from donors with rhabdomyolysis and acute kidney injury (AKI) may show discolored appearance. The transplant surgeons may be unwilling to accept a…
2018 American Transplant Congress
10-Year Outcomes of Renal Transplantation from Circulatory Death Donors with Increased Terminal Creatinine
Y. Tomita, K. Iwadoh, I. Nakajima, S. Fuchinoue.
Surgery III, Tokyo Women's Medical University, Tokyo, Japan.
Background: To alleviate chronic renal graft shortages in Japan, donation after circulatory death (DCD) is an increasingly used organ resource. Organs from DCD donors with…
2018 American Transplant Congress
The Effect of Tacrolimus Trough Level and Intrapatient Variability on the Transplant Outcomes in Kidney Transplantation
J. Lee,¹ J. Lee,¹ Y. Jung,¹ D. Kim,¹ S. Song,² J. Lee,³ J. Lee,¹ M. Kim,¹ S. Kim,¹ Y. Kim,¹ B. Kim,⁴ K. Huh.¹
¹Surgery, Yonsei University College of Medicine, Seoul, Korea; ²Surgery, Ewha Womans University, School of Medicine, Seoul, Korea; ³Surgery, CHA Bundang Medical Center, CHA University, Seongnam, Korea; ⁴Internal Medicine (Nephrology), Yonsei University College of Medicine, Seoul, Korea.
Background: Tacrolimus (TAC) is the mainstay of immunosuppression for kidney transplantation (KT). Although TAC has a narrow therapeutic index, appropriate trough concentrations of TAC have…
2018 American Transplant Congress
The Infusion with a Difference: Patient Experiences with Belatacept
H. Murad, D. Malhotra, E. Cohen, W. Asch.
Yale University, New Haven, CT.
Introduction: The results of the BENEFIT trial led to the FDA approval of the novel anti-rejection agent belatacept (bela) in 2011. In addition to its…
2018 American Transplant Congress
Chronic Changes on Time Zero Living Donor Allograft Biopsy Portraits Worse Donor Renal Function
A. Nishio-Lucar,¹ J. Murphy,² A. Sites,³ H. Cathro,² A. Doyle,¹ K. Warburton,¹ A. Agarwal.⁴
¹Medicine, University of Virginia, Charlottesville, VA; ²Pathology, University of Virginia, Charlottesville, VA; ³Transplant Services, University of Virginia, Charlottesville, VA; ⁴Surgery, University of Virginia, Charlottesville, VA.
The prognostic ability of zero hour biopsy (ZHB) in renal allografts has not been fully elucidated. ZHB utility predicting living kidney donor (LKD) renal recovery…
2018 American Transplant Congress
Pinching an Inch in Kidney Transplantation: Subcutaneous Depth as a Risk Factor for Wound Complications
R. Ruiz, T. Cox, K. Wicklund, N. Jennings, N. Onaca, G. Testa, T. Anthony, H. Fernandez, J. Bayer, G. McKenna.
Baylor All Saints Medical Center, Fort Worth.
Wound complications after kidney transplant (KTx) consume valuable resources, including prolonged hospital stays and increased costs. Known risk factors include immunosuppression exposure, diabetes, and obesity…
2018 American Transplant Congress
A “Multi-Omic” Analysis of Proteome and Metabolome for Acute Rejection and PVAN in Kidney Transplantation
T. Sigdel, J. Yang, M. Sarwal.
Surgery, UCSF, San Francisco.
Background: Most effort in identifying biomarkers have used gene expression analyses. Proteomics and metabolomics are useful to identify surrogate biomarkers in monitoring transplanted kidney and…
2018 American Transplant Congress
Increased Gene Expression of TGF-b in Renal Transplant Patients with Polyomavirus BK Viremia
W. Yin.
SURGERY, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chia I, Taiwan; School of Medicine, Tzu Chi University, Hualien, Taiwan.
Objective: We aimed to investigate the roles of cytokines during polyomavirus BK (BKV) reactivation in renal transplant patients.Materials and Methods: Fortyeight renal allograft recipients were…
2018 American Transplant Congress
TACI-Ig as a Desensitization Agent in a Rat Model of Antibody Mediated Rejection
N. Wilson,¹ B. Verhoven,² B. Boldt,² N. Bath,² X. Ding,¹ R. Redfield III.²
¹Medicine/Nephrology, University of Wisconsin, Madison, WI; ²Surgery/Transplant, University of Wisconsin, Madison, WI.
We examined the effect of APRIL/BLyS blockade on B cell lineages & donor specific antibody (DSA) in preclinical rodent model as a novel desensitization strategy.…