2018 American Transplant Congress
Extended Experience Using Tocilizumab (Anti-IL6R, TCZ) for the Treatment of Chronic Antibody Mediated Rejection (CABMR)
Introduction: Disruption of the IL-6/IL-6R pathways may have benefits in treating allograft rejection. We reported our experience with anti-IL-6R (TCZ) as a treatment for CABMR…2018 American Transplant Congress
Modifiable Causes of Racial Disparities in Living Donor Kidney Transplant
Racial disparities between White and non-White patients in receiving living donor kidney transplants (LDKT) are large and widespread. Yet, the causes of this disparity are…2018 American Transplant Congress
Evaluating the Impact of Pre-Transplant Malignancy on Outcomes after Kidney Transplantation: A National Database Analysis over a Twenty-Two Year Period
Dept. of Surgery, University of Wisconsin, Madison, WI.
Introduction: Patients with a history of malignancy prior to kidney transplantation are known to develop more post-transplant malignancies and have inferior outcomes. However, there have…2018 American Transplant Congress
Effect of Acute Vascular Inflammation (v) on Death Censored Graft Failure (DCGF) Following Kidney Transplant (KTx)
The impact of acute vascular inflammation in acute cellular or humoral rejection following KTx, and the effect of isolated vascular inflammatory lesions on late DCGF,…2018 American Transplant Congress
Antihypertensive Medication Use after Kidney Transplant: Practice Variation and Clinical Outcomes
Hypertension is common among kidney transplant (KTx) recipients, but the impact of antihypertensive medication (AHM) choice on patient and graft outcomes is not well defined.We…2018 American Transplant Congress
Development of an Individualized Online Shared Decision Making Tool for Kidney Transplant Candidates
Background: Inadequate knowledge hinders informed decision making in kidney transplant candidates. We conducted qualitative interviews and focus groups with patients and providers to inform development…2018 American Transplant Congress
Impact of Rapid Discontinuation of Prednisone on Kidney Transplant Outcomes in At-Risk Subpopulations: An OPTN/SRTR Analysis
1Public Health, U of MN, Mpls, MN; 2Surgery, U of MN, Mpls, MN.
Objective: Successful RDP (rapid discontinuation of prednisone <1 week post-tx) after kidney transplant (KTx) has been reported for low-risk populations. We studied the impact of…2018 American Transplant Congress
Non-Invasive Diagnostic of Renal Allograft Rejection via Urine Metabolites Using NMR-Spectroscopy
Introduction and BackgroundPost-transplant surveillance for acute rejection is typically based on regular monitoring of serum creatinine levels and consecutive biopsies upon functional renal impairment. Attempts…2018 American Transplant Congress
Presence of Donor Specific Antibodies is Associated with Accelerated Podocyte Detachment
University of Michigan, Ann Arbor; University of Kansas, Kansas City.
Introduction: Both indication and 10-yr surveillance biopsy data point to the important role of progressive glomerular disease in intermediate and long-term allograft outcomes. As all…2018 American Transplant Congress
TORC1 Inhibition Protects Activated Human Regulatory T Cells from Self-Inflicted Damage via Granzyme B
Transplantation Research Center, BWH, Harvard Medical School, Boston, MA.
The safety and efficacy of adoptive transfer of regulatory T cells (Tregs) are being extensively investigated in ongoing clinical trials. However, these trials have been…
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