2019 American Transplant Congress
Are We Underestimating The Number Of Paired Kidney Exchange Transplants In The United States? Relationship Insights From The National Kidney Registry
1Epidemiology, UNC Chapel Hill, Chapel Hill, NC, 2Johns Hopkins University, Baltimore, MD
*Purpose: Despite an overall decline in the number of living donor kidney transplants (LDKTs) since 2005, Kidney Paired Donation (KPD) rates have increased over the…2019 American Transplant Congress
Opening the Doors of Hope: HIV-Positive Living Kidney Donation
Duke University Medical Center, Durham, NC
*Purpose: Living donation (LD) has been allowed under the HOPE Act since 2013, yet to date there have been no HIV+ LD organ transplants performed…2019 American Transplant Congress
Ex Vivo Normothermic Perfusion Of Discarded Human Kidneys Reveals Cold-storage-induced Renal Fibrinogen And Provides A Platform For Therapeutic Repair
*Purpose: The purpose of this study was to: 1) determine the cause of microvascular obstructions that arise during ex vivo normothermic perfusion (NMP) of human…2019 American Transplant Congress
RNA Sequencing Guided Identification of Shared mRNAs in Human Kidney Allograft Recipients with Acute T Cell Mediated Rejection or Active Antibody Mediated Rejection
*Purpose: T cell help is essential for B cell production of antibodies to donor organ HLA. Because T cell-B cell interactions contribute to anti-allograft immunity,…2019 American Transplant Congress
Achieving Robust Targeting of Antibody-Conjugated Nanoparticles Delivered during Ex Vivo Machine Perfusion of Human Kidneys
*Purpose: In this study we seek to improve targeted nanoparticle (NP) delivery during ex-vivo normothermic machine perfusion through fibrinolysis for more homogenous treatment of human…2019 American Transplant Congress
Assessment of the Relationship between Inflammation and Glomerular Filtration Rate
*Purpose: Since the inflammatory phenomena that occur after transplantation are decisive factors for developing renal rejection, we decided to study how the elevation of some…2019 American Transplant Congress
Evidence to Support the Use of Kidney Allograft Function as a Clinical Trial Outcome Measure
Nephrology, University of British Columbia, Vancouver, BC, Canada
*Purpose: As a biomarker, kidney allograft function has been rejected as clinical trial outcome measure because it is not predictive of allograft survival. In this…2019 American Transplant Congress
Impact Of The Provision Of Transplant Information On Access To First And Repeat Kidney Transplantation
Nephrology, University of British Columbia, Vancouver, BC, Canada
*Purpose: To determine whether the provision and relative impact of transplant information differs in incident ESRD patients and patients with a history of previous transplant…2019 American Transplant Congress
Implementation of a De Novo Belatacept Protocol
1Massachusetts General Hospital, Boston, MA, 2Wake Forest, Winston-Salem, NC
*Purpose: The use of belatacept with basiliximab induction and maintenance MMF/prednisone when compared to cyclosporine is associated with superior long-term patient and graft survival but…2019 American Transplant Congress
Belatacept Use in High Kidney Donor Profile Index Kidney Transplant Recipients
1Pharmacy, Barnes-Jewish Hospital, St. Louis, MO, 2Veloxis Pharmaceuticals, Cary, NC
*Purpose: To determine whether the use of belatacept is associated with renal function preservation in kidney transplant recipients from donors with a kidney donor profile…
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