2019 American Transplant Congress
Optimal Timing of Hepatitis C Treatment among HIV/HCV Co-Infected End-Stage Renal Disease Patients: Pre vs. Post-Transplant
*Purpose: End-stage renal disease (ESRD) patients co-infected with HCV and HIV have access to effective treatment options for HCV infection. However, they also have access…2019 American Transplant Congress
CNI-Free Therapy with Iscalimab (anti-CD40 mAb) Preserves Allograft Histology Compared to Standard of Care after Kidney Transplantation
*Purpose: To assess if calcineurin (CNI)-free therapy with iscalimab preserves the quality of transplanted kidney grafts.*Methods: Iscalimab (CFZ533) is a new, fully human, Fc-silenced, non-depleting,…2019 American Transplant Congress
Comparison of Isolated Transplant Glomerulopathy with Chronic Antibody-Mediated Rejection in Regards to Endothelial-to-Mesenchymal Transition and Graft Survival
*Purpose: Transplant glomerulopathy (TG) has been proposed to be a component of chronic antibody-mediated rejection (CAMR). However, a substantial number of patients with TG do…2019 American Transplant Congress
Increase in Proinflammatory CD14++CD16+ Monocytes in Samples from Aspiration Cytology Compared with Peripheral Blood in Kidney Transplant Patients with Borderline Rejection
*Purpose: Monocytes comprise a heterogeneous population divided according to the membrane expression level of their molecules. One of these populations is the CD14++CD16+, which presents…2019 American Transplant Congress
Evaluation of Delayed Renal Allograft Function after DCD with New Biomarkers in Donor Blood
Beijing Chaoyang Hospital, Capital Medical University, Beijing, China
*Purpose: To explore the relationship between new biomarkers in donor blood and delayed graft function (DGF) after DCD kidney transplantation, and to evaluate the clinical…2019 American Transplant Congress
A2 To B Kidney Transplants Under Kidney Allocation System: A Prospective Study Of Anti A Titers And Correlation With Outcomes
Vanderbilt University, Nashville, TN
*Purpose: The UNOS KAS system incorporates A2 to B deceased donor kidney transplants (DDKTx) to improve access and reduce disparities in wait times for B…2019 American Transplant Congress
Race-Sex Effects on Immune Response Potential during Tacrolimus Minimization Therapy in Stable Renal Allograft Recipients
*Purpose: African American renal transplant recipients (RTR) exhibit more immunoreactivity to allografts which may contribute to chronic rejection. This study investigated race-sex influences on ex…2019 American Transplant Congress
A Retrospective Observational Analysis of Tacrolimus Metabolism Rate: No Evidence for Impact on Renal Function
*Purpose: A previous publication found that fast metabolisers of tacrolimus had inferior renal function compared to slow metabolisers in a Caucasian population (Thölking et al.,…2019 American Transplant Congress
Impact of HLA-DR Matching on HLA-DQ Matching Status and the Development of Anti-HLA-DQ De Novo DSA under Calcineurin Inhibitor or Belatacept Immunosuppression
*Purpose: De novo donor-specific HLA antibodies (dnDSA) that develop after kidney transplantation target more frequently allo-HLA-DQ antigens in comparison to other allo-HLA antigens. Yet, organ…2019 American Transplant Congress
Estrogen Mediated Protection in Renal Ischemia Reperfusion Injury (IRI) is Extrinsic to the Kidney
*Purpose: IRI causes morbidity in renal transplantation and other surgical scenarios. A better understanding of the molecular mechanisms of IRI is required so that strategies…
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