2019 American Transplant Congress
Extracellular Vesicles (EV) Mediate Antibody-Independent Tubular Senescence via Cyclin-Dependent Kinase Inhibitors p21/p16 in Antibody-Mediated Rejection (AMR)
*Purpose: Recent data suggest a strong correlation between kidney injury and the occurrence of accelerated senescence process, known as “Inflammaging”. However, the role of TEC…2019 American Transplant Congress
Patient Centered AUC-Monitoring of Tacrolimus Using Capillary Microsampling
Oslo University Hospital, Rikshospitalet, Oslo, Norway
*Purpose: To reduce unwanted side effects of Tacrolimus (Tac), improvement of dosing is warranted. Therapeutic drug monitoring (TDM) of Tac based on trough concentrations (C0)…2019 American Transplant Congress
Basiliximab versus T-cell Depleting Induction Therapy in Elderly Kidney Transplant Recipients
MedStar Georgetown Transplant Institute, Washington, DC
*Purpose: The ideal induction therapy for elderly kidney transplant recipients is not known. Given concerns about increased risk of infection and malignancy and perceived decreased…2019 American Transplant Congress
Development of a Pharmacy Collaborative Practice Agreement to Improve Efficiency and Management of Prescribing in a Renal Transplant Clinic
*Purpose: This study describes the development of a Collaborative Pharmacy Practice Agreement (CPPA) between transplant pharmacists and physicians and assesses change in prescription volume and…2019 American Transplant Congress
Timing and Donor-Specific Antibodies, but Not C4d Deposition, Determine Leukocyte Infiltration in Renal Allograft Biopsies with the Histological Picture of Antibody-Mediated Rejection
*Purpose: Diagnosis of antibody-mediated rejection following kidney transplantation can be challenging, given the limited specificity of individual histological parameters and time-dependent occurrence of histological confounders.…2019 American Transplant Congress
Donor Renal Macrophages in Post-Transplant Ischemia/Reperfusion Injury (IRI): Role of IL-1R8 in Modulating Fate, Phenotype and Function
Mario Negri Institute, Ranica, Italy
*Purpose: Post-transplant (tx) IRI activates TLR/IL-1R on tissue resident leukocytes initiating innate immune response. We studied how donor renal resident macrophages (rMF) respond to post-tx…2019 American Transplant Congress
The Combination of 3-Month Estimated Glomerular Filtration Rate and Proteinuria is a Valuable Tool for Evaluating Long-Term Kidney Graft Survival
*Purpose: Estimated glomerular filtration rate (eGFR) measured at 1 year is the usual outcome used to predict the long-term graft survival in the field of…2019 American Transplant Congress
Significance of Histopathologic Features for Predicting Progression in Patients with Transplant Glomerulopathy
National Clinical Research Center of Kidney Diseases, Nanjing, China
*Purpose: Transplant glomerulopathy (TG) represents a major cause of long-term allograft failure and is the leading cause of overall post-transplant proteinuria. We aimed to determine…2019 American Transplant Congress
ilearnKAS: An Animated Video to Educate African Americans about Key Concepts of Kidney Allocation
University at Buffalo, Buffalo, NY
*Purpose: ilearnKAS is a iteratively-designed patient-engaged mobile educational animated video developed with guidance from patients, providers, Self-efficacy and Multimedia Learning Theories designed for African American…2019 American Transplant Congress
Conversion from Tacrolimus Immediate Release to Tacrolimus Extended Release (Envarsus XR®): A Real World Cohort Highlighting Dosing Variability among Patients
*Purpose: Tacrolimus extended release (TacER) (Envarsus XR®) has become an attractive alternative to tacrolimus immediate release (TacIR) due to its once daily dosing scheme, favorable…
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