Articles tagged "Kidney transplantation"

2019 American Transplant Congress
Global Kidney Exchange
D. N. Bozek¹, O. Ekwenna¹, S. Paloyo², T. Dunn³, K. Krawiec⁴, S. Rees⁵, A. Roth⁶, M. Zimmerman⁷, J. Punch⁸, R. Forbes⁹, C. Marsh¹⁰, C. Kuhr¹¹, J. Rogers¹², M. Tan¹³, L. Basagoitia¹⁴, R. Correa-Rotter¹⁵, J. Ortiz¹, P. Sindhwani¹, M. A. Rees¹
¹University of Toledo Medical Center, Toledo, OH, ²University of the Philippines – Philippine General Hospital; St. Luke’s Medical Center, Manila, Philippines, ³University of Minnesota, Minneapolis, MN, ⁴Duke University, Durham, NC, ⁵Alliance for Paired Donation, Perrysburg, OH, ⁶Stanford University, Stanford, CA, ⁷Froedert Hospital-Medical College of Wisconsin, Milwaukee, WI, ⁸University of Michigan, Ann Arbor, MI, ⁹Vanderbilt University Medical Center, Nashville, TN, ¹⁰Scripps Green Hospital, San Diego, CA, ¹¹Virginia Mason Medical Center, Seattle, WA, ¹²Wake Forest Baptist Medical Center, Winston-Salem, NC, ¹³Piedmont Hospital, Atlanta, GA, ¹⁴ProRenal, ., Mexico, ¹⁵INNSZ, Mexico City, Mexico
*Purpose: Poverty prevents more kidney transplants (KTs) worldwide than any other barrier. Global kidney Exchange (GKE) is a mechanism to overcome this barrier.*Methods: In high-income…
2019 American Transplant Congress
Positron Emission Tomography (PET-CT) Global Coronary Flow Reserve (CFR) Stratifies Cardiovascular Risk among Renal Transplant (RTx) Candidates
M. Minder, S. Mason, J. Ethington, R. McCubrey, D. Min, N. Sekaran, J. Orford, D. Morris, S. Anand, T. Srinivas
Intermountain Healthcare, Murray, UT
*Purpose: Chronic kidney disease (CKD) and diabetes (DM) are both associated with increased risk of coronary artery disease and Major Adverse Cardiovascular Events (MACE). The…
2019 American Transplant Congress
Differences of Gut Microbiota Composition between Donor and Recipient May Predict 1-Year Graft Function
J. Kim¹, H. Cho², J. Park³, J. Jeong¹, M. Kwak⁴, B. Kim⁴, D. Kim¹, J. Lee⁵, B. Kim⁶, Y. Kim¹, H. Lee¹
¹Seoul National University Hospital, Seoul, Korea, Republic of, ²Chungbuk National University Hospital, Cheongju, Korea, Republic of, ³Kangwon National University Hospital, Seoul, Korea, Republic of, ⁴Chunlab Inc., Seoul, Korea, Republic of, ⁵Seoul National University Boramae Hospital, Seoul, Korea, Republic of, ⁶Hallym University, Chuncheon, Korea, Republic of
*Purpose: Signals derived from gut microbiota are critical for the development and maintenance of the human immune system. In view of kidney transplantation (KT), allograft…
2019 American Transplant Congress
Three-Year Outcomes of Highly-Sensitized Kidney Transplant Recipients Desensitized with Imlifidase (IdeS)
E. Huang¹, J. Choi¹, A. Vo¹, A. Peng¹, R. Najjar¹, S. Sethi¹, C. Kjellman², L. Winstedt², N. Ammerman¹, S. C. Jordan¹
¹Cedars Sinai Medical Center, Los Angeles, CA, ²Hansa Medical, Lund, Sweden
*Purpose: The HLA-incompatible (HLAi) barrier has been traversed using desensitization therapies with IVIg, rituximab and/or plasmapheresis, although antibody-mediated rejection (ABMR) continues to be observed in…
2019 American Transplant Congress
Kidney Allograft Recipient Absence of Myeloperoxidase Decreases Donor-Specific Antibody Titers and Attenuates Antibody-Mediated Allograft Rejection
S. Miyairi, N. Dvorina, A. Valujuskikh, W. M. Baldwin 3rd, R. L. Fairchild
Immunology, Cleveland Clinic Lerner Institute, Cleveland, OH
*Purpose: The incidence of antibody-mediated kidney graft rejection continues to increase. We previously reported that dysregulated donor-specific antibody (DSA) responses were induced in B6.CCR5-/- mice…
2019 American Transplant Congress
A Prognostic Model to Identify Deceased Donor Kidney Transplant Recipients at High Risk for Delayed Graft Function
S. Kawakita, J. L. Beaumont, M. J. Everly
Terasaki Research Institute, Los Angeles, CA
*Purpose: We have previously identified pre-transplant risk factors for delayed graft function (DGF) in deceased donor kidney transplant (DDKT) recipients and built a machine learning…
2019 American Transplant Congress
Urinary Biomarkers- CXCL9 and CXCL10 for Non-Invasive, Early Diagnosis of Rejection in Pediatric Renal Transplantation
R. P. George¹, B. Hanberry², I. Dave², B. Lee², R. Garro¹, C. McCracken², B. Warshaw¹
¹Pediatrics, Emory University and Children's Healthcare of Atlanta, Atlanta, GA, ²Pediatrics, Emory University, Atlanta, GA
*Purpose: Renal transplantation is the treatment of choice for End Stage Renal Disease, but requires strict medication adherence and lifelong surveillance for rejection, infection and…
2019 American Transplant Congress
Should Kidney Retransplants Be Performed From Either Extended Criteria Donor Or Donation After Cardio Circulatory Death Donors?
D. Harriman, V. Gurram, A. Farney, J. Rogers, G. Orlando, C. Jay, A. Reeves-Daniel, A. Mena-Gutierrez, M. Gautreaux, W. Doares, S. Kaczmorski, R. Stratta
Wake Forest Baptist Medical Center, Winston-Salem, NC
*Purpose: Donation after brain death expanded criteria donors (ECD) and donation after cardiocirculatory death (DCD) standard criteria donors (DCD/SCD) increase the donor organ pool but…
2019 American Transplant Congress
Eculizumab in Kidney Transplant Recipients with Atypical Hemolytic Uremic Syndrome – Single Center Experience
A. Bhalla, S. Alasfar, N. Alachkar
Division of Transplant Nephrology, Johns Hopkins Hospital, Baltimore, MD
*Purpose: Atypical hemolytic uremic syndrome (aHUS) is caused by genetic mutations of components of the alternative complement pathway in 60-70% of cases; and has a…
2019 American Transplant Congress
Belatacept Conversion for Calcineurin Inhibitor-Associated Thrombotic Microangiopathy in Kidney Transplant Recipients
S. A. Muhsin, K. Safa, H. M. Gilligan, E. C. Heher, W. W. Williams, D. M. Wojciechowski
Nephrology Division, MGH, Boston, MA
*Purpose: Thrombotic Microangiopathy (TMA) in kidney transplant recipients is a serious complication that can cause graft loss. It can be associated with immunosuppressive medications such…