2019 American Transplant Congress
Long-Term Outcomes of Eculizumab-Treated Positive Crossmatch Recipients: Allograft Survival, Histologic Findings, and Natural History of the Donor-Specific Antibodies
*Purpose: We aimed to determine long-term outcomes for eculizumab-treated, positive crossmatch (+XM) kidney transplant recipients as compared with +XM and age-matched negative crossmatch (−XM) control…2019 American Transplant Congress
Persistent Mixed Chimerism, Immune Reconstitution, and Tolerance in Recipients of HLA Matched Kidney and Hematopoietic Cell Transplants
Stanford University School of Medicine, Stanford, CA
*Purpose: We evaluated the immune reconstitution of recipients of HLA matched combined kidney and hematopoietic cell transplants after tolerance induction*Methods: Twenty nine recipients of living…2019 American Transplant Congress
Efficacy and Safety with Empagliflozin in Renal Transplant Recipients with Post-Transplant Diabetes Mellitus
*Purpose: Post-transplant diabetes mellitus (PTDM) is a highly prevalent condition following renal transplantation, associated with increased risk of cardiovascular disease and impaired patient survival. Sodium-glucose…2019 American Transplant Congress
Solving Target Recognition and Activation Mediated by Non-HLA Agonistic Antibodies Targeting ETAR
*Purpose: Endothelin-1 type A receptor (ETAR) exhibits multiligand binding abilities and may signal upon natural ligand Endothelin-1 (ET-1) and non-HLA ETAR-agonistic IgG (ETAR-IgG)-mediated stimulation similar…2019 American Transplant Congress
Increase in Deceased Donor Acceptance Rate After Implementing Uniform Acceptance Criteria
Piedmont Transplant Institute, Atlanta, GA
*Purpose: Over 100,000 candidates are listed for kidney transplant in the United States, yet less than 20,000 patients are transplanted annually. In 2013, over 2,500…2019 American Transplant Congress
Is Kidney Transplantation Actually a Cost-Effective Alternative Also for Older Patients?
*Purpose: We aimed to study the health economic effects of kidney transplantation in a population of kidney transplant candidates > 65 years of age.*Methods: We…2019 American Transplant Congress
Using Ensembles of Machine Learning Classifiers to Maximize the Accuracy and Stability of Molecular Biopsy Interpretation
*Purpose: The Molecular Microscope diagnostic system (MMDx), based on microarray gene expression, uses ensembles of machine learning classifiers rather than single genes, gene sets, or…2019 American Transplant Congress
A 15-year Experience With Kidney Transplant In Undocumented Immigrants: Outcomes And An Argument For Transplantation
1Surgery, Boston Medical Center, Boston, MA, 2Boston University School fo Medicine, Boston, MA
*Purpose: We investigated whether undocumented immigrants have similar outcomes after renal transplant compared to documented recipients.*Methods: We retrospectively analyzed records of adult renal transplant recipients…2019 American Transplant Congress
Kidney Transplants Outcomes from Deceased Donors with Acute Kidney Injury
*Purpose: Due to the shortage of organs for transplantation, kidney transplants (KT) from marginal donors including donors with acute kidney injury (AKI) are expanding. Although…2019 American Transplant Congress
Predicting Transplant Rejection by a Composite Urinary Injury Score
Department of Surgery, UCSF, San Francisco, CA
*Purpose: While sequencing or SNP-based methods of quantifying donor-derived cell-free DNA (dd-cfDNA) from plasma have been used to detect allograft rejection, they remain expensive and…
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