Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Causal Factors and Clinical Impact of Urinary Tract Infections in Renal Transplanted Patients: An Observational Retrospective Study
C. Alfieri, F. Tripodi, D. Cresseri, M. Gandolfo, M. Campise, A. Regalia, P. Messa, G. Castellano
Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico Milano, Milan, Italy
*Purpose: This study aims to examine the etiology of urinary tract infections (UTIs) in a cohort of KTxps, trying to identify their potential predisposing factors…
2022 American Transplant Congress
Comparison of CT Volumetry versus Nuclear Renography for Predicting Remaining Kidney Function After Uninephrectomy in Living Kidney Donors
S. Eum¹, H. Lee¹, E. Ko¹, H. Cho², H. Yoon³, S. Shin³, C. Yang¹, B. Chung¹
¹Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, Seoul, Korea, Republic of, ²Department of Urology, Seoul St. Mary's Hospital, Seoul, Korea, Republic of, ³Division of Nephrology, Department of Internal Medicine, Incheon St. Mary's Hospital, Incheon, Korea, Republic of
*Purpose: Computed tomography (CT) and nuclear renography are used to determine kidney procurement strategy in living kidney donors (LKDs). The present study investigated which modality…
2022 American Transplant Congress
Discovery of Risk Factor Control Targets Using Machine Learning and Network Analysis for One-Year Renal Allograft Dysfunction
Y. Lee¹, M. Hong², J. Kong³, O. Kwon⁴, C. Jung⁵, J. Yang⁶, M. Kim⁷, H. Han⁸, S. Nam⁹
¹Division of Nephrology, Department of Internal medicine, CHA Bundang Medical Center, Seongnam, Korea, Republic of, ²Department of Biomedical Informatics,, CHA University School of Medicine, Seongnam, Korea, Republic of, ³Department of Nephrology,, BHS Hanseo Hospital, Pusan, Korea, Republic of, ⁴Department of Surgery, College of Medicine, Han Yang University, Seoul, Korea, Republic of, ⁵Department of Surgery, Korea University Anam Hospital, Seoul, Korea, Republic of, ⁶Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea, Republic of, ⁷Department of Surgery, Yonsei University College of Medicine, Seoul, Korea, Republic of, ⁸Department of Biomedical Informatics, CHA University School of Medicine, CHA University, Seongnam, Korea, Republic of, ⁹Department of Ophthalmology, CHA Bundang Medical Center, Seongnam, Korea, Republic of
*Purpose: Early identification of graft loss risk and timely therapeutic intervention are crucial for preventing late renal allograft failure and improving long-term graft function. This…
2022 American Transplant Congress
Impact of the Covid-19 Pandemic on Longitudinal Molecular Surveillance in the KOAR Registry
T. Alhamad¹, A. Malone¹, D. Mandelbrot², P. M. Anand³, H. M. Wadei⁴, G. Shekhtman⁵, N. Agrawal⁵, K. Pinney⁵, K. Qu⁵, A. Desai⁶
¹Washington University, St. Louis, MO, ²University of Wisconsin, Madison, WI, ³Medical University of South Carolina, Charleston, SC, ⁴Mayo Clinic Jacksonville, Jacksonville, FL, ⁵CareDx, Brisbane, CA, ⁶Loyola University Medical Center, Maywood, IL
*Purpose: The SARS-CoV2 pandemic increased the complexity of delivering routine clinical care and laboratory services for immunosuppressed kidney transplant (KTx) recipients. We evaluated how the…
2022 American Transplant Congress
The Successful Use of De Novo Belatacept with Reduced Dose Tacrolimus to Mitigate the Risks of Delayed Graft Function in Kidney Transplantation
E. Siskind¹, J. Splinter¹, C. Taing¹, A. Adekile², S. Njim¹, S. Shah¹, R. Plews³, D. Conti⁴, S. Patel²
¹Center for Transplantation, University Medical Center of Southern Nevada, Las Vegas, NV, ²University Medical Center of Southern Nevada, Las Vegas, NV, ³Center for Transplantation, Albany Medical Center, Albany, NY, ⁴Albany Medical Center, Albany, NY
*Purpose: The new kidney allocation system has caused increased organ travel times and therefore increased cold ischemia time. Furthermore, the change in the priority to…
2022 American Transplant Congress
Randomized, Phase 4 Study Evaluating the Pharmacokinetics and Tolerability of the New Tacrolimus Tablet Formulation (Tacrobell Tab) in Kidney Transplant Recipients
A. Han¹, E. Cho¹, H. Y. Woo¹, C. Ara¹, H. Lee², Y. Kim³, Y. Park⁴, J. Oh⁴, S. Min¹, J. Ha¹
¹Department of Surgery, Seoul National University College of Medicine, Seoul, Korea, Republic of, ²Seoul National University Hospital, Seoul, Korea, Republic of, ³Department of Nephrology, Seoul National University College of Medicine, Seoul, Korea, Republic of, ⁴Department of Clnical Pharmacology, Seoul National University Hospital, Seoul, Korea, Republic of
*Purpose: Previous twice-a-day tacrolimus formulations available were capsular and of limited dose formulations (0.5mg, 1mg). Recently a new tablet formulation of tacrolimus with more diverse…
2022 American Transplant Congress
Donor/Recipient Variabilities and Dd-cfdna Level
I. Gani¹, L. Mulloy¹, R. Mallavarapu¹, M. Saeed¹, R. Kapoor², A. Mirza¹
¹Augusta University Medical Center, Augusta, GA, ²Southwest Kidney Institute, Phoenix, AZ
*Purpose: Donor-derived cell-free DNA such as AlloSure (CareDx) is used as a non-invasive biomarker for allograft rejection and allograft injury as increased dd-cfDNA is observed…
2022 American Transplant Congress
Dual Deceased Donor Kidney Transplants: Maximizing Utilization of Suboptimal Kidneys
S. Nagaraju, S. Vaishnav, K. Boggs, T. Cook, A. Jones, J. B. Africa
Renal Transplant, Charleston Area Medical Center, Charleston, WV
*Purpose: To demonstrate that dual transplant of marginal kidneys is an underutilized strategy to minimize discard rates and mitigate organ shortage.*Methods: We compared dual kidney…
2022 American Transplant Congress
Recipient Neutrophil Production of Myeloperoxidase is Required for NK Cell Activation During Acute Antibody Mediated Allograft Rejection
Y. Mitsui¹, D. Ueda¹, S. Miyairi¹, N. Dvorina¹, K. S. Keslar¹, A. Valujskikh¹, B. William¹, R. Fairchild²
¹Inflammation & Immunity, Cleveland Clinic, Cleveland, OH, ²Cleveland Clinic Foundation, Cleveland, OH
*Purpose: Dysregulated donor-specific antibody (DSA) responses are induced in B6.CCR5-/- mice transplanted with complete MHC mismatched A/J kidney allografts and are required for rejection of…
2022 American Transplant Congress
Repeat Kidney Transplantation from Living Donors Offers Comparable Outcomes as First Transplantation
N. Oh, K. Lee, J. Rhu, J. Kim, G. Choi, J. Park, J. Joh
Department of Surgery, Samsung Medical Center, Seoul, Korea, Republic of
*Purpose: The number of patients relisted for repeat kidney transplantation is increasing due to prolonged survival after first transplantation. This study is designed to compare…