Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Single Center Retrospective Study Examining the Safety of the New Potassium- Binders for Post-Operative Hyperkalemia in Kidney Transplant Recipients
S. Kapoor¹, A. Campbell², Y. Azzi¹, L. E. Liriano-Ward³, T. Shertel⁴, W. Xiao⁵, D. U. Nnani⁶, S. Farghaly¹, S. Yun⁷, E. Akalin¹, M. Ajaimy¹
¹Einstein-Montefiore Transplant Center, Bronx, NY, ²Montefiore Medical Center, Bronx, NY, ³Transplant, Montefiore Medical Center, Bronx, NY, ⁴-, -, AL, ⁵Albert Einstein College of Medicine, Folsom, CA, ⁶Pharmacy, Montefiore Medical Center, Bronx, NY, ⁷Montefiore Medical Center, New York, NY
*Purpose: We aimed to evaluate the safety and efficacy of two potassium-binders (Patiromer and Sodium Zirconium Cyclosilicate (SZC) in early post-transplant hyperkalemia treatment of kidney…
2022 American Transplant Congress
Effect of Schisandra Sphenanthera Extract on Pharmacokinetics of Tacrolimus in Pediatric Renal Transplant Recipients
J. Jiang¹, H. Zhang¹, X. Su¹, S. Wu¹, Y. Chen², W. Chen², J. Li², C. Wu², L. Yang², L. Liu², C. Wang²
¹Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
*Purpose: Wuzhi tablet (Schisandra sphenanthera extract) is a promising tacrolimus-sparing agent in adult renal transplant recipients, while its effect in pediatric recipients remains unclear. The…
2022 American Transplant Congress
Adding Epitope Compatibility To Deceased Donor Kidney Allocation Criteria: Recommendations From An Online Public Deliberation
L. Edwards¹, R. Sapir-Pichhadze², P. Keown³, S. Bryan¹
¹School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada, ²McGill University, Montreal, QC, Canada, ³Department of Medicine, University of British Columbia, Vancouver, BC, Canada
*Purpose: With increasing demand for kidneys and a scarce supply, ways to reduce rejection and improve transplant outcomes are needed. One possibility is using epitope…
2022 American Transplant Congress
In Vitro Fertilization Use Among Female Kidney Transplant Recipients
L. A. Coscia¹, J. M. Konel², M. Bowring³, S. Constantinescu⁴, M. J. Moritz⁵
¹Transplant Pregnancy Registry International, Philadelphia, PA, ²Wayne State University School of Medicine, Detroit, MI, ³Johns Hopkins University School of Medicine, Baltimore, MD, ⁴Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, ⁵Surgery, Lehigh Valley Health Network, Allentown, PA
*Purpose: Infertility is common among female kidney transplant recipients (KTRs). In vitro fertilization (IVF) is a potential option. The purpose of this study was to…
2022 American Transplant Congress
First Report of Xenotransplantation from a Pig to Human Recipient
J. Stern¹, V. Tatapudi¹, B. Lonze¹, Z. Stewart¹, M. Mangiola¹, M. Wu¹, S. Mehta¹, E. Weldon¹, R. Dieter¹, N. Lawson¹, A. Griesemer², B. Parent¹, G. Piper¹, P. Sommer¹, S. Cawthon¹, B. Sullivan¹, N. Ali¹, R. A. Montgomery¹
¹NYU Langone Transplant Institute, New York, NY, ²CUMC, New York, NY
*Purpose: Xenotransplantation of genetically edited pig organs into human recipients can solve the global scarcity of organs for transplantation. Humans lack the α1,3-Gal glycan ubiquitously…
2022 American Transplant Congress
Predictors of Response to Belatacept Conversion in Kidney Transplant Patients with Chronic Active Antibody-Mediated Rejection
D. Kumar¹, R. Winstead¹, H. Iftikhar¹, R. Minniti¹, S. Khorsandi¹, J. Christensen¹, I. Yakubu¹, I. Moinuddin¹, L. Kamal¹, P. Halloran², G. Gupta¹
¹Virginia Commonwealth University, Richmond, VA, ²University of Alberta, Edmonton AB, AB, Canada
*Purpose: Chronic active antibody mediated rejection (cABMR) is a major cause of kidney transplant (KT) loss. Current therapies have unclear efficacy and side effects. We…
2022 American Transplant Congress
Outcomes of Hlai Kidney Transplants in Patients with Cpra 100% After Desensitization
A. A. Vo¹, J. Tang¹, S. Williamson¹, C. Meyers¹, E. Huang¹, X. Zhang², M. Haas³, A. Peng¹, R. Najjar¹, S. Supreet¹, N. Ammerman¹, K. Lim¹, M. Gillespie¹, N. Badash¹, S. Jordan¹
¹Comprehensive Transplant Center, Cedars Sinai Medical Ctr, Los Angeles, CA, ²HLA Laboratory, Cedars Sinai Medical Ctr, Los Angeles, CA, ³Pathology, Cedars Sinai Medical Ctr, Los Angeles, CA
*Purpose: The KAS implementation was aimed at increasing access to kidney transplantation in highly HLA sensitized (HS) patients. However, combining desensitization (DES) + KAS could…
2022 American Transplant Congress
A2/A2B to B Kidney Transplantation Outcomes: A Single-Center 5 Year Experience
A. El Chediak, S. Shawar, M. Fallahzadeh, I. Feurer, S. Rega, J. L. Triozzi, D. Shaffer
Vanderbilt University Medical Center, Nashville, TN
*Purpose: The new kidney allocation system (KAS) instituted in 2014 allowed organ procurement organizations to allocate A2/A2B to B candidates preferentially was meant to improve…
2022 American Transplant Congress
Identification of Highly-Effective Donor-Reactive CD4⁺CD8α^lo T Cells in CTLA4Ig-Treated Renal Allograft Recipient Monkeys
M. Kubo, K. Sasaki, L. Lu, V. Vujevich, A. Thomson, M. Ezzelarab
Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA
*Purpose: Potent CD4+CD8αlo effector T cells have been reported in transplant (tx) patients. . We evaluated the incidence and function of CD4+CD8αloT cells in renal…
2022 American Transplant Congress
Clinical Outcomes with IR-tac to LCP-tac Conversion in a Kidney Transplant Population
F. Bartlett¹, J. Newman¹, T. Sprague¹, S. Patel¹, N. Rao², E. Andrade², V. Rohan², M. Casey², D. Dubay¹, D. Taber¹
¹Pharmacy, Medical University of South Carolina, Charleston, SC, ²Medical University of South Carolina, Charleston, SC
*Purpose: LCP-Tac is approved for conversion from IR-Tac in kidney transplant patients with a conversion rate of 70-80%. Studies have demonstrated similar efficacy and safety…