Articles tagged "Kidney transplantation"

2019 American Transplant Congress
Renal Transplantation in Patients Older Than 60 Years with High Comorbidity. Is There a Survival Benefit? A Multicenter Study in Argentina
G. D. Fragale¹, G. A. Laham², L. Bisignano³, A. Antik³, P. M. Raffaele⁴, M. Fortunato⁴, H. Trimarchi⁵, V. Pomeranz⁵, R. Maldonado⁶, N. Matamala⁶, N. C. Imperiali⁷, M. C. Giordani⁷, M. F. Taylor⁸, J. M. Ciappa⁸, J. L. De La Fuente⁹, S. Naser¹⁰, G. Soler Pujol²
¹Nephrology, Hospital Universitario Austral, Derqui, Argentina, ²Nephrology, CEMIC, Buenos Aires, Argentina, ³INCUCAI, Buenos Aires, Argentina, ⁴Fundacion Favaloro, Buenos Aires, Argentina, ⁵Hospital Britanico de Buenos Aires, Buenos Aires, Argentina, ⁶Clinica Velez Sarsfield, Cordoba, Argentina, ⁷Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁸Crai Sur, Buenos Aires, Argentina, ⁹Hospital Privado Universitario de Cordoba, Cordoba, Argentina, ¹⁰Hospital Privado Universitario de Cordoba, Buenos Aires, Argentina
*Purpose: The impact of renal transplantation (RT) in the elderly with comorbid conditions is a matter of concern. Our aim was to assess the impact…
2019 American Transplant Congress
Early Tacrolimus Trough Attainment in De Novo Kidney Transplant Recipients Treated with LCP-Tacrolimus (LCPT) vs. Immediate-Release Tacrolimus (IR-Tac)
K. Budde¹, S. Bunnapradist², S. J. Patel³, D. R. Stevens³, U. Meier-Kriesche³, B. Suwelack⁴
¹Charité University Medicine Berlin, Berlin, Germany, ²UCLA Medical Center, Los Angeles, CA, ³Veloxis Pharmaceuticals Inc., Cary, NC, ⁴University Hospital of Münster, Münster, Germany
*Purpose: Early achievement of therapeutic tacrolimus concentrations has been associated with reduced rates of acute rejection. A prospective, randomized, controlled study demonstrated safe and efficacious…
2019 American Transplant Congress
Impacts of Mycophenolate Mofetile Addition to Very Low Exposure Everolimus and Calcineurine Inhibitor Based Immunosuppression in De Novo Kidney Transplantation 5 Years Results
Y. Watarai¹, S. Narumi¹, T. Tomosugi¹, M. Okada¹, K. Futamura², M. Tsujita², T. Hiramitsu¹, T. Kobayashi³, N. Goto²
¹Transplant Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan, ²Transplant Nephrology, Nagoya Daini Red Cross Hospital, Nagoya, Japan, ³Kidney Transplant Surgery, Aichi Medical University, Nagoya, Japan
*Purpose: Prospective randomized study of MMF addition to everolimus (EVR) based immunosuppression was evaluated in clinical outcomes as well as protocol biopsies findings and donor…
2019 American Transplant Congress
Phenotype and Course of Renal Tubular Cell Death during Cold Ischemia versus Cold Ischemia Followed by Transplant
S. Jain¹, R. Plenter², T. Nydam², A. Jani¹
¹Renal Division, University of Colorado, Aurora, CO, ²Transplant Microsurgery Program, University of Colorado, Aurora, CO
*Purpose: Treatments of Delayed graft function (DGF) are lacking. Prolonged cold ischemia (CI) is a risk factor for DGF but the pathways by which CI…
2019 American Transplant Congress
Post-Transplant Lymphopenia is Associated with Higher Risk of Graft Failure, Death and Viral Infections
A. Dujardin¹, M. Lorent², C. Kerleau¹, S. Brouard³, M. Giral¹
¹Nephrology, Nantes University Hospital, Nantes, France, ²UMR_S 1246, INSERM, Nantes, France, ³CRTI UMR 1064, Inserm, Nantes, France
*Purpose: The transplantation field needs biomarkers to assess the level of immunosuppression. In this study, we aimed to analyze the independent correlation between the number…
2019 American Transplant Congress
Individualized Preconditioning for ABO-Incompatible Living Donor Kidney Transplantation: An Initial Report of 48 Cases from China
X. -. Wang
Department of Urology/Institute of Urology, West China Hospital of Sichuan University, Chengdu, China
*Purpose: Typically, the majority of centres that perform ABO incompatible (ABOi) kidney transplantation use fixed preconditioning protocols regardless of the initial titer. As experience in…
2019 American Transplant Congress
Kidney Transplants Following Donation after Circulatory Death and Donation after Brain Death Have Similar Early Outcomes
M. Hobeika¹, D. Nguyen², E. Graviss², A. Gaber¹, H. Podder¹, S. Yi¹, S. Kuten³, S. Patel³, R. Knight¹
¹J.C. Walter, Jr. Transplant Center, Houston Methodist Hospital, Houston, TX, ²Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Houston, TX, ³Pharmacy, Houston Methodist Hospital, Houston, TX
*Purpose: Donation after circulatory death (DCD) is common in the US, comprising 18.3% of the deceased donor pool in 2017. Recipient outcomes following DCD kidney…
2019 American Transplant Congress
Thymoglobulin Versus Alemtuzumab Induction in High Immunologic Risk Kidney Transplants
J. Lockridge¹, J. Pryor¹, D. Norman¹, A. Olyaei²
¹OHSU, Portland, OR, ²Pharmacy, OHSU, Portland, OR
*Purpose: The optimal induction immunosuppressive therapy to prevent kidney transplant rejection remains controversial, specifically among high immunologic risk patients. Our aim was to compare the…
2019 American Transplant Congress
Donor-Derived Carbapenem-Resistant Klebsiella Pneumoniae Infection after Renal Transplantation
B. Liu, M. Wang, F. Zeng, S. Chang, N. Gong, G. Chen, Z. Chen
Institute of Transplantation, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China
*Purpose: We summarized the experience of diagnosis and treatment of donor-derived carbapene-resistant klebsiella pneumoniae (CRKP) infection after renal transplantation.*Methods: From January 2015 to June 2018,…
2019 American Transplant Congress
Long-Term Influence of Arteriosclerosis in Kidney Grafts Proven by a Zero-Hour Biopsy
Y. Kakuta¹, M. Okumi¹, T. Kanzawa¹, K. Unagami², H. Ishida¹, K. Tanabe¹
¹Urology, Tokyo Women's Medical University, Tokyo, Japan, ²Organ Transplant Medicine, Tokyo Women's Medical University, Tokyo, Japan
*Purpose: Histopathological assessment of kidney grafts by zero-hour biopsies adds unique information concerning organ quality that is not available on clinical grounds. The most prevalent…