2020 American Transplant Congress
Clinical Implications of Tacrolimus Time in Therapeutic Range in Urban Renal Transplant Recipients Under an Early Corticosteroid Withdrawal Protocol
University of Illinois at Chicago, Chicago, IL
*Purpose: Tacrolimus displays wide inter- and intra-patient variability, necessitating therapeutic drug monitoring. Assessing the duration of time in therapeutic range (TTR) is an additional tool…2020 American Transplant Congress
Evaluation of Cytomegalovirus Prophylaxis in Low and Intermediate Risk Kidney Transplant Recipients Receiving Lymphocyte-Depleting Induction
Hartford Hospital, Hartford, CT
*Purpose: This study evaluates if choice and duration of Cytomegalovirus (CMV) prophylaxis based on donor (D) and recipient (R) CMV serostatus impacts the incidence of…2020 American Transplant Congress
Using Quality Metrics to Improve Access to Living Donor Kidney Transplantation
*Purpose: Living donor kidney transplants (LDKT) are an excellent option for patients with kidney disease. Delays in donor evaluations can impact donor satisfaction as well…2020 American Transplant Congress
Donor-Derived Cell-Free DNA May Not Discriminate Rejection in Kidney Transplant Recipients with a Prior Allograft in Place
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) is an injury biomarker discriminating rejection in kidney transplant (KTx) patients (pts). However, its performance when stratified by rejection risk…2020 American Transplant Congress
Basiliximab Induction in the Obese: One Size Does Fit All
*Purpose: Surgical advancements allow more obese (BMI> 30 kg/m2) patients to receive a renal transplant. The original clinical and pharmacokinetic (PK) trials in transplantation immunosuppression…2020 American Transplant Congress
Early Compensatory Hypertrophy Circumvents Hyperfiltration Injury in Adult Recipients of Small Pediatric Deceased Donor Kidneys
1Mayo Clinic Alix School of Medicine, Phoenix, AZ, 2Mayo Clinic, Phoenix, AZ
*Purpose: Donor-to-recipient body weight ratios have been shown to influence kidney transplant (KT) outcomes. For small pediatric donors, this mismatch is far more pronounced and…2020 American Transplant Congress
Liver Biopsy Does Not Change Transplant Candidacy Decisions for Hepatitis B Virus Positive Living Donor Kidney Transplant Recipients
Asan Medical Center, Seoul, Korea, Republic of
*Purpose: Hepatitis B virus (HBV) infection of kidney transplantation (KT) recipients is associated with increased overall mortality and progression of liver disease after KT. Liver…2020 American Transplant Congress
Brincidofovir for Treatment of Disseminated Human Adenovirus Infection in Pediatric Solid Organ Transplant Recipients
*Purpose: Brincidofovir (BCV) is an investigational antiviral drug with potency against Human Adenovirus (HAdV). We describe four cases of disseminated HAdV infection treated with (BCV)…2020 American Transplant Congress
The Role and Impact of Transplant Pharmacist Evaluation in a Pre-Kidney Transplant Clinic
Pharmacy Practice and Transplant Surgery, University of Illinois at Chicago, Chicago, IL
*Purpose: The Centers for Medicare and Medicaid Services’ interpretative guidelines for conditions of participation for transplant centers define the transplant pharmacist’s role ambiguously. Limited evidence…2020 American Transplant Congress
Bortezomib Exhibits Therapeutic Implication in Renal Interstitial Fibrosis after Kidney Transplantation by Inhibiting Akt-mTOR-P70S6K-Smurf2 Pathway and Stabilizing IκBα Protein
Jiangsu Province Hospital, Nanjing, China
*Purpose: Allograft interstitial fibrosis and fibrogenesis significantly exacerbate the progression of chronic allograft disease (CAD) and are essential therapeutic targets. Epithelial‐mesenchymal transition (EMT) is recognized…
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