Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Analysis of 1000 Protocol Kidney Biopsies: Complications, Benefits, and Predictive Potential of Prior Sensitization
M. Eslami¹, J. Patel², S. Karzai¹, D. T. Collins¹, C. Liu¹, J. Jonsson¹, R. Wali¹, J. B. Piper¹
¹Surgery, Inova Fairfax Hospital, Falls Church, VA, ²General Surgery, Pennsylvania State University, State College, PA
*Purpose: Protocol biopsy of kidney transplants can allow for early recognition of treatable findings, both immunologic and non-immunologic. This comes with the risk of biopsy…
2020 American Transplant Congress
Renal Allograft Surveillance with Allospecific T-cytotoxic Memory Cells Which Express CD154
V. Rohan, A. Alqassieh, N. Patel, K. Soliman, V. Rao
Surgery, Medical University of South Carolina, Charleston, SC
*Purpose: Allo-antigen-specific T-cytotoxic memory cells (TcM) which express CD40 ligand (CD154) in overnight lymphocyte co-culture are strongly associated with acute cellular rejection (ACR) seen in…
2020 American Transplant Congress
Optimal Recipient Selection and Surgical Complications in Dual Kidney Transplantation
S. Patel¹, S. Chang², R. Sussman³, R. Plews¹, R. Lopez-Soler⁴, D. Conti¹
¹Kidney and Pancreas Transplantation, Albany Medical Center, Albany, NY, ²Nephrology and Transplantation, University at Buffalo, Buffalo, NY, ³Center for Donation and Transplantation, Albany Medical Center, Albany, NY, ⁴Renal Transplant Program, Hines VA Medical Center, Chicago, IL
*Purpose: Kidney allocation has recently been modified to allow enhanced utilization of dual kidney transplants (DKT) to reduce organ discards. This study evaluates surgical complications…
2020 American Transplant Congress
Dual Donor-Recipient Intervention with Recombinant Human C1 Inhibitor Prevents Delayed Graft Function and Reduces Antibody-Mediated Rejection after Kidney Transplantation in Non-Human Primates
C. Blanton¹, J. Reyes¹, M. Eerhart¹, P. Chlebeck¹, M. Springer¹, Y. Ponstein², E. vanAmersfoort², J. Torrealba³, Y. Yankol¹, A. D’Alessandro¹, L. Fernandez¹
¹University of Wisconsin, Madison, WI, ²Pharming Technologies BV, Leiden, Netherlands, ³Pathology, UTSouthwestern, Dallas, TX
*Purpose: Patients with delayed graft function (DGF) are at increased risk for rejection and inferior graft survival. Complement activation during brain death and ischemia reperfusion…
2020 American Transplant Congress
Large Academic Center Experience with Treatment of Suspected/Confirmed Kidney Transplant Active Antibody Mediated Rejection
J. T. Reece¹, B. A. Steiner², V. Bhoj¹, N. Aqui¹, R. D. Bloom³, J. Trofe-Clark⁴
¹Transfusion Medicine Div, Univ of Pennsylvania, Philadelphia, PA, ²Pharmacy, Hosp of Univ of Pennsylvania, Philadelphia, PA, ³Renal Div, Univ of Pennsylvania, Philadelphia, PA, ⁴Pharmacy, Hospital of University of Pennsylvania, Philadelphia, PA
*Purpose: Therapeutic plasma exchange (TPE) and intravenous immunoglobulin (IVIG) are common active antibody mediated rejection (ABMR) treatments in kidney transplant recipients (KTRs), but with unclear…
2020 American Transplant Congress
Kidney Transplantation from Hepatitis C Infected Donors to Hepatitis C Negative Recipients: Does Organs Selection Matter?
B. Rawashdeh¹, L. Luu¹, Z. Sahli¹, E. McCracken¹, A. Doyle², K. Brayman¹, A. Agarwal¹
¹Transplant Surgery, University of Virginia, Charlottesville, VA, ²Division of Transplant Nephrology, University of Virginia, Charlottesville, VA
*Purpose: Recently, there has been a marked increase in the availability and use of kidneys from hepatitis C virus (HCV) positive deceased donors for transplantation.…
2020 American Transplant Congress
Acute Rejection in the First Year is a Risk Factor for Subsequent Cardiac Events in Kidney Transplant Recipients
F. Aziz, R. Tao, S. Parajuli, N. Garg, D. Mandelbrot, B. Astor, A. Djamali
University of Wisconsin, Madison, WI
*Purpose: Cardiac events (CE) remain an important cause of morbidity and mortality after the first post-transplant year. We sought to determine whether acute rejection in…
2020 American Transplant Congress
Early Calculation of the Tacrolimus Concentration-to-Dose Ratio Does Not Predict Outcomes after Renal Transplantation
K. Schütte-Nütgen, I. Bartmann, B. Suwelack, S. Reuter
Department of Internal Medicine D, University Hospital Münster, Münster, Germany
*Purpose: There is emerging interest in the concentration-to-dose (C/D) ratio of tacrolimus (Tac) as it is linked to outcomes after renal transplantation (RTx). Recently, we…
2020 American Transplant Congress
Fibrosing Cholestatic Hepatatitis in Post Renal Transplant and Successful Treatment with Newer DAA Therapy
V. Siddini
Nephrology, Manipal Hospital, Bangalore, India
*Purpose: Fibrosing cholestatic hepatitis is often fatal post renal transplantation. we report a case of successful treatment of FCH and complete recovery*Methods: A 53 year…
2020 American Transplant Congress
Old World Monkeys Are Not Ideal Transplantation Models for Testing CMAHKO (TKO or GTKO/CMAHKO) Pig Kidneys
T. Yamamoto¹, H. Iwase¹, D. Patel¹, A. Jagdale¹, J. Foote¹, D. Ayares², D. Anderson¹, D. E. Eckhoff¹, D. K. Cooper¹, H. Hara¹
¹University of Alabama at Birmingham, Birmingham, AL, ²Revivicor, Blacksburg, VA
*Purpose: Triple-knockout (TKO) pigs are likely to be an optimal source of organs for transplantation into human recipients, many of whom do not have natural…