Articles tagged "Kidney transplantation"

2020 American Transplant Congress
The Scenario of Delayed Graft Function in Brazil
T. V. Sandes-Freitas¹, M. Mazzali², R. Manfro³, H. Tedesco-Silva⁴, L. Andrade⁵, V. Garcia⁶, E. Davi-Neto⁷, R. Esmeraldo⁸, C. Oliveira⁹, E. Lasmar¹⁰, R. Madeira¹¹, G. Ferreira¹², G. Meira¹³, F. Cavalcanti¹⁴, A. Bignelli¹⁵, D. Carvalho¹⁶, D. Pedroso¹⁷, L. Deboni¹⁸, A. Silva e Filho¹⁹, A. Vicari³, M. Sousa², .. on behalf of 'DGF multicêntrico' group²⁰
¹Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Brazil, ²HC/UNICAMP, Campinas, Brazil, ³HCPA/UFRGS, Porto Alegre, Brazil, ⁴Hospital do Rim, São Paulo, Brazil, ⁵HC-Botucatu/UNESP, Botucatu, Brazil, ⁶Santa Casa de Porto Alegre, Porto Alegre, Brazil, ⁷HC/FMUSP, São Paulo, Brazil, ⁸H. Geral de Fortaleza, Fortaleza, Brazil, ⁹HUWC/UFC, Fortaleza, Brazil, ¹⁰H. Universitário São José, Belo Horizonte, Brazil, ¹¹H. Felício Rocho, Belo Horizonte, Brazil, ¹²Santa Casa de Juiz de Fora, Juiz de Fora, Brazil, ¹³Santa Casa de Montes Claros, Montes Claros, Brazil, ¹⁴Real Hospital Português, Recife, Brazil, ¹⁵H. Universitário Cajuru, Curitiba, Brazil, ¹⁶H. São Francisco na Providencia de Deus, Rio de Janeiro, Brazil, ¹⁷H. Santa Isabel, Blumenau, Brazil, ¹⁸H. Municipal São José, Joinville, Brazil, ¹⁹H. Israelita Albert Einstein, São Paulo, Brazil, ²⁰ABTO, São Paulo, Brazil
*Purpose: Unicenter Brazilian studies reported high incidences (50-70%) of delayed graft function (DGF). This is a multicenter Brazilian study aimed to evaluate the incidence, the…
2020 American Transplant Congress
Kidney Transplantation in Inherited Kidney Diseases
Y. Caliskan¹, H. Yazici², R. Ouseph¹, Y. Ozluk³, H. Randall⁴, E. Demir², F. Savran Oguz⁵, A. Turkmen², M. S. Sever², K. Lentine¹
¹Division of Nephrology, Saint Louis University, Saint Louis, MO, ²Division of Nephrology, Istanbul Faculty of Medicine, Istanbul, Turkey, ³Department of Pathology, Istanbul Faculty of Medicine, Istanbul, Turkey, ⁴Center for Abdominal Transplantation, Saint Louis University, Saint Louis, MO, ⁵Department of Medical Biology, Istanbul Faculty of Medicine, Istanbul, Turkey
*Purpose: We aimed to evaluate the kidney transplant (KTx) recipients with inherited kidney diseases and investigate the causal genetic variants in recipients with undetermined etiology.*Methods:…
2020 American Transplant Congress
Flow Cytometric Characterization of Regulatory Cell Populations Expanded Ex Vivo from PBMCs of Kidney Transplant Recipients
S. Tripathi¹, P. L. Martin-Moreno², G. J. Kavalam¹, A. Chandraker¹
¹Renal, Brigham and Women's Hospital, Boston, MA, ²Nephrology, Clinica Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain
*Purpose: We have previously shown that it is possible to generate alloantigen-specific regulatory T cell lines and clones that prolong allograft survival upon infusion in…
2020 American Transplant Congress
Two-Year Post-Transplant eGFR as a Surrogate Outcome of Allograft Survival in Kidney Transplant Recipients
S. Yu, E. Lee, W. Zhang, D. Segev, J. Garonzik-Wang, A. Massie
Johns Hopkins, Baltimore, MD
*Purpose: Graft failure is a major cause of morbidity and mortality in kidney transplant recipients. However, trials aimed to assess the effect of interventions on…
2020 American Transplant Congress
A Single-Center Analysis of Using Allele-Level 11 HLA Loci Information on cPRA and Organ-Allocation Points in Kidney Transplant Candidates
C. Maguire¹, P. Muluhngwi¹, E. Kransdorf², L. Gragert³, A. R. Tambur¹
¹Northwestern University, Chicago, IL, ²Cedars-Sinai Heart Institute, Beverly Hills, CA, ³Tulane University, New Orleans, LA
*Purpose: Calculated panel reactive antibodies (cPRA) is used by the United Network for Organ Sharing (UNOS) to quantify degree of HLA sensitization and assign priority…
2020 American Transplant Congress
Life-Supporting Pig Thymus Plus Kidney Transplantation Leads to Generation of New Baboon T-Cells and Swine-Specific Hyporesponsiveness
Y. Okumura¹, K. Takeuchi¹, Y. Ariyoshi¹, T. Pomposelli¹, L. Boyd¹, D. Alper¹, K. Miyake¹, K. Okubo¹, S. Arn¹, D. Ayares², M. Lorber³, M. Sykes¹, D. Sachs¹, K. Yamada¹
¹Columbia Center for Translational Immunology, Columbia University, New York, NY, ²Revivicor Inc., Blacksburg, VA, ³Lung BioTechnology PBC, Silver Spring, MD
*Purpose: We have achieved greater than 6-month survivals in baboons that received vascularized thymus plus kidney xenotransplants (VT+K XTx). We assessed the thymic function and…
2020 American Transplant Congress
Quantifying the Number of ESRD Patients Who Might Benefit from Bariatric Surgery to Achieve Listing for Transplant
B. Orandi¹, P. MacLennan¹, S. Mehta¹, J. Grams¹, R. Stahl¹, R. Cannon¹, D. Anderson¹, M. Hanaway¹, C. Young¹, J. Purvis¹, N. Terrault², C. Lewis¹, J. Locke¹
¹University of Alabama at Birmingham, Birmingham, AL, ²University of Southern California, Los Angeles, CA
*Purpose: Mounting evidence suggests bariatric surgery may play a role in helping obese ESRD patients achieve sufficient weight loss to be transplant-eligible. We sought to…
2020 American Transplant Congress
Textbook Outcome as a Composite Quality Metric in Kidney Transplantation
J. L. Han, A. J. Logan, J. M. Sneddon, G. L. Brock, K. W. Washburn, A. D. Schenk
Department of Surgery, Division of Transplantation, The Ohio State University Wexner Medical Center, Columbus, OH
*Purpose: Textbook outcomes (TO) describe ideal patient outcomes following specific surgical procedures and are useful composite quality metrics for patients, providers and payors. We aimed…
2020 American Transplant Congress
Steroid Withdrawal and Lymphocyte Subsets in Graft Capillary Blood versus Peripheral Blood in Low Immunological Risk Kidney Transplant Patients: Randomized, Parallel Group, Controlled Clinical Trial
T. Vazquez Sanchez, A. Caballero, J. Alonso-Titos, V. Lopez, E. Sola, M. Cabello, E. Gutierrez Vilchez, M. Martínez-Esteban, P. Ruiz Esteban, J. Delgado, D. Hernandez
Regional University Hospital, Malaga, Spain
*Purpose: Whether steroid withdrawal can modulate the subclinical inflammatory response after a kidney transplant is unknown.*Methods: We undertook a controlled multicenter clinical trial involving 105…
2020 American Transplant Congress
Uremic Symptoms: A Patient-Reported Outcome That is Associated with Access to Kidney Transplantation and Waitlist Mortality among Kidney Transplant Candidates
K. Taylor¹, N. Chu², Z. Shi², E. Rosello³, S. Kunwar², P. Butz³, S. Norman⁴, D. Crews⁵, K. Greenberg⁵, D. Segev³, T. Shafi⁶, M. McAdams-DeMarco³
¹Johns Hopkins University School of Nursing, Baltimore, MD, ²Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD, ³Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, ⁴Division of Nephrology, University of Michigan, Ann Arbor, MI, ⁵Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁶Division of Nephrology, University of Mississippi Medical Center, Jackson, MS
*Purpose: Patient-reported symptoms of uremia - pruritis, anorexia and fatigue - reflect incomplete removal of uremic toxins by dialysis and are likely one of the…