Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Cortex Recipient Weight Ratio is a Predictor for Short-Term Renal Function After Living Donor Kidney Transplant
K. Takahashi¹, K. Furuya¹, J. Usui², T. Kimura³, S. Fukuda⁴, A. Hoshi³, T. Yoshino³, H. Nishiyama³, T. Oda¹, K. Yamagata²
¹Gastrointestinal and Hepatobiliary Pancreatic Surgery, University of Tsukuba, Tsukuba, Japan, ²Nephrology, University of Tsukuba, Tsukuba, Japan, ³Urology, University of Tsukuba, Tsukuba, Japan, ⁴Nursing, University of Tsukuba, Tsukuba, Japan
*Purpose: Renal function early after living donor kidney transplant (LDKT) depends on “nephron mass” in the renal graft, and “nephron mass” can be quantified as…
2022 American Transplant Congress
Impact of Donor-Recipient Age Discrepancy in Living Donor Kidney Transplantation – The Need for Better Matching
N. K. Prabhu¹, V. Villani¹, K. P. Samy¹, D. Sudan¹, K. Ravindra¹, W. Irish²
¹Surgery, Duke University Medical Center, Durham, NC, ²Surgery, East Carolina University, Greenville, NC
*Purpose: The Kidney Allocation System (KAS) was implemented in 2014 to address donor-recipient matching in deceased donor kidney transplantation, with the goal of maximizing life-years…
2022 American Transplant Congress
Viral-Specific Cytotoxic T-Cell Responses in Hla-Sensitized Kidney Transplant Patients Maintained on Everolimus and Low Dose Tacrolimus
R. Zhang¹, S. Ge¹, M. Chu¹, J. Kahwaji², A. Karasyov¹, D. Lovato¹, A. Vo², J. Choi², M. Toyoda¹, S. Jordan²
¹Transplant Immunology Laboratory, Cedars Sinai Medical Center, Los Angeles, CA, ²Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA
*Purpose: Post-transplant immunosuppression with “everolimus + reduced dose tacrolimus” (Ev + Taclow) is reported to reduce the risk of viral infections compared to standard doses…
2022 American Transplant Congress
Center Volume and Transplant Outcomes in Adult Kidney Transplant Recipients; A Competing Risk Analysis
A. Azhar¹, E. Defor¹, L. Kamal¹, D. Bandyopadhyay¹, B. Tanriover², G. Gupta¹
¹Virginia Commonwealth University, Richmond, VA, ²University of Arizona, Tuscon, AZ
*Purpose: The precise effect of center volume is a much-debated topic in the field of transplantation. Several studies have shown better post-transplant outcomes in higher…
2022 American Transplant Congress
Predictors of Short and Long Term Outcomes of Donor After Cardiac Death (DCD) versus Donor After Brain Death (DBD) Kidney Transplantation from Supra Marginal Donors ( D4). A Machine Learning Analysis (MLA) of NHSBT Registry Data Since Year 2000
H. Sharma¹, A. Sharma², T. Gunawardhane¹, B. Devkaran¹, K. Kapoor¹, S. Mehra¹
¹Royal Liverpool University Hospital, Liverpool, United Kingdom, ²Loyola University Chicago, Chicago, IL
*Purpose: Marginal Donor 4- D4 ( Donor Risk Index ≥1.50 ) Matching was introduced as a part of new Kidney allocation scheme in the UK…
2022 American Transplant Congress
Direct Health Care Costs Before and After Kidney Transplantation in Germany – A Longitudinal Analysis Based on Claims Data
S. Ronicke¹, K. Budde¹, D. Schmidt², W. Düttmann¹, M. G. Naik¹, C. J. Wagner³, J. Freitag³, B. Osmanodja¹
¹Department of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany, ²Buisiness Unit IT, Charité - Universitätsmedizin Berlin, Berlin, Germany, ³AOK Nordost Statutory Health Insurance Fund, Berlin, Germany
*Purpose: Kidney transplantation can improve long-term survival and quality of life in transplant candidates with end-stage renal disease and has shown to have long-term economic…
2022 American Transplant Congress
Reduced Dose Mycophenolate Does Not Increase the Risk of Rejection Following Renal Transplantation
L. Bowman¹, A. Webb¹, S. Desai², D. Patino³, V. Subramanian⁴, S. Mohammed⁵, M. Gosselin⁶, K. Robichaux⁵, J. Buggs⁴, A. Kumar⁷
¹Transplant Pharmacy, Tampa General Hospital, Tampa, FL, ²Western University of Osteopathic Medicine, Pomoma, CA, ³Michigan State University College of Human Medicine, Lansing, MI, ⁴Transplant Surgery, Tampa General Hospital, Tampa, FL, ⁵University of South Florida, Tampa, FL, ⁶University of Tampa, Tampa, FL, ⁷Morsani College of Medicine, University of South Florida, Tampa, FL
*Purpose: Mycophenolic acid (MPA) exposure correlates inversely with the risk of acute rejection; however, evidence also suggests that systemic MPA exposure also determines the extent…
2022 American Transplant Congress
Antibody Response and Molecular Graft Surveillance in Kidney Transplant Recipients Following Sars-CoV-2 Vaccination
N. M. Ali¹, J. Miles², S. Mehta¹, V. Tatapudi¹, Z. Stewart¹, B. Lonze¹, M. Mangiola¹, C. DiMaggio¹, E. Weldon¹, I. Saeed¹, J. Leonard¹, R. Herati¹, J. Thomas¹, J. Michael¹, C. Hickson¹, K. Cartiera¹, R. Montgomery¹
¹Transplant Institute, NYU Langone Health, New York, NY, ²CareDx, Brisbane, NY
*Purpose: Preliminary studies suggest that kidney transplant recipients (KTRs) show diminished humoral responses to SARS-CoV-2 vaccination. Although reports of allograft rejection after SARS-CoV-2 vaccination have…
2022 American Transplant Congress
Stem Cell Donor-Derived CPRA Better Reflects Sensitization Than Current CPRA
K. Lindblad¹, C. Murphey², P. Lalli³, J. Lunz⁴, L. Gragert⁵
¹UNOS, Richmnd, VA, ²Southwest Immunodiagnostics, Inc., San Antonio, TX, ³Carolinas Medical Center, Charlotte, NC, ⁴LifeLink Foundation Transplant Immunology Lab, Tampa, FL, ⁵Tulane University School of Medicine, New Orleans, LA
*Purpose: The OPTN Histocompatibility Committee proposes replacing the current calculated panel reactive antibody (CPRA), based on HLA haplotype frequencies from ~14,000 deceased kidney donors, with…
2022 American Transplant Congress
Impact of Recipient Obesity on Kidney Transplantation Outcome: A Retrospective Cohort Study with a Matched Comparison
A. Buemi
Surgery, Cliniques Universitaires Saint Luc, Bruxelles, Belgium
*Purpose: The aim of this study was to evaluate the effect of recipient obesity on posttransplant complications and patient and graft survival.*Methods: A single-institution, retrospective…