2022 American Transplant Congress
Validation of the iBox Surrogate End Point in CNI Free, Belatacept Treated Patients (BENEFIT & BENEFIT-EXT)
*Purpose: The iBox is a prognostication system for long-term kidney allograft survival, developed with mostly patients under a CNI based immunosuppression. Patients treated with a…2022 American Transplant Congress
IL-15 Signaling is Required for the Maintenance of Tissue Resident Memory T Cells in Chronic Allograft Rejection
1Starzl Transplantation Institute, Pittsburgh, PA, 2JN Biosciences, Mountain View, CA
*Purpose: Currently, no immunotherapies have been clinically proven to prevent or treat chronic rejection. IL-15 is known to support memory T cell homeostasis. However, it…2022 American Transplant Congress
Tacrolimus Exposure Estimation in Stable Kidney Transplant Recipients Using Maximum A Posteriori Bayesian Approach
*Purpose: Tacrolimus exhibits interpatient pharmacokinetic variability that impacts clinical responses and requires routine trough therapeutic drug monitoring. Tacrolimus troughs do not consistently predict area under…2022 American Transplant Congress
Urinary Cell CTOT-04 Signature is Diagnostic of Glomerulitis in Kidney Allograft Biopsies
1Nephrology, Weill Cornell-NYPH, New York, NY, 2Pathology, Weill Cornell-NYPH, New York, NY
*Purpose: Antibody mediated rejection is a significant complication after kidney transplantation and is an important cause of allograft failure. In the multicenter CTOT-04 study, we…2022 American Transplant Congress
Treading the Paradigm Shift: A Single Center Comparative Study of Outcomes Between Pre-Emptive and Early Kidney Transplant with Non Pre-Emptive Kidney Transplant Recipients Innational Kidney and Transplant Institute
*Purpose: To compare the 3-year outcome of pre-emptive and early kidney transplant recipients versus non pre-emptive recipients in our institution from January 2013 to December…2022 American Transplant Congress
Correlation of Donor-Derived Cell-Free DNA with Histology and Molecular Diagnoses of T-cell Mediated Rejection in Kidney Transplant Biopsies
1Virginia Commonwealth University, Richmond, VA, 2University of Alberta, Edmonton, AB, Canada
*Purpose: We have reported the correlation of donor-derived cell-free DNA (dd-cfDNA) with histologic and molecular diagnosis (MMDx) of kidney transplant biopsies (Gupta et al, Transplantation…2022 American Transplant Congress
A More Equitable Transplant Evaluation: What Patient-Level Factors Impact Time to Kidney Transplant Evaluation Completion?
Houston Methodist, Houston, TX
*Purpose: The kidney transplant evaluation process can take months or years to complete depending on patient health status and level of engagement. This study examines…2022 American Transplant Congress
Outcomes in Renal Transplant Recipients Receiving Pre-Transplant Financial Assistance Through the American Kidney Fund
*Purpose: Pre-transplant financial assistance for insurance premiums is available for eligible patients through the American Kidney Fund (AKF), but this funding ends within the first…2022 American Transplant Congress
Kidney Transplant Recipients with Diabetic Mellitus Demand Larger Doses of Mycophenolate Mofetil
Kidney transplant surgery and Urology, Sapporo City General Hospital, Sapporo, Japan
*Purpose: To monitor blood concentration of immunosuppressants, therapeutic drug monitoring (TDM) is required at any point after kidney transplantation (KT) to prevent kidney graft from…2022 American Transplant Congress
Outcomes of Very Small Pediatric Donor Kidneys Utilizing Belatacept-Based Immunosuppression in Adult Recipients
1University of Utah Health, Salt Lake City, UT, 2Medical University of South Carolina, Johnston, SC
*Purpose: Due to the lack of data utilizing belatacept as primary immunosuppression for adult recipients of very small pediatric donor kidneys, this study seeks to…
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