Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Clinical Significance of Late Antibody-Mediated Rejection without Donor Specific Anti-hLA Antibodies
J. Lee¹, E. Kim¹, S. Yang¹, S. Kim¹, B. Lim², H. Choi³, B. Kim⁴, B. Kim⁴, M. Ju⁵, M. Kim¹, S. Kim¹, Y. Kim¹, K. Huh¹
¹Department of Transplantation Surgery, Severance Hospital, Seoul, Korea, Republic of, ²Department of Pathology, Yonsei University College of Medicine, Seoul, Korea, Republic of, ³Department of Internal Medicine, Gangnam Severance Hospital, Seoul, Korea, Republic of, ⁴Department of Internal Medicine, Severance Hospital, Seoul, Korea, Republic of, ⁵Department of Surgery, Gangnam Severance Hospital, Seoul, Korea, Republic of
*Purpose: Late onset antibody-mediated rejection (AMR) is a leading cause of kidney allograft failure. Its diagnosis has been based on a combination of morphologic, immunohistologic…
2020 American Transplant Congress
Frailty and Its Implications for Early Post-Transplant Outcomes in Kidney Transplant Recipients
J. Kim, P. Chen, M. Minkovich, O. Famure, Y. Li
Toronto General Hospital, Toronto, ON, Canada
*Purpose: Frailty, a measure of physiologic reserve, is associated with poor early outcomes, like early hospital readmission (EHR) and delayed-graft function (DGF) in kidney transplant…
2020 American Transplant Congress
Assessment of Infectious Complications Following ABO-Blood Group Incompatible Renal Transplant
J. Banbury¹, T. Loosier¹, C. Lin², K. Gutierrez¹
¹University of Alabama at Birmingham Hospital, Birmingham, AL, ²Center for Clinical and Translational Science, University of Alabama at Birmingham, Birmingham, AL
*Purpose: In response to the ongoing organ shortage, ABO-incompatible (ABOi) renal transplant (RT) provides an alternative option for patients with end-stage kidney disease. Literature suggests…
2020 American Transplant Congress
Effect of Everolimus and Reduced Calcineurin Inhibitors on Biopsy Proven BK Virus Associated Nephropathy
Z. S. Zaky, M. Spinner, B. Stephany, S. Nurko, R. Fatica, J. Augustine, E. Poggio
Cleveland Clinic, Cleveland, OH
*Purpose: BK virus-associated nephropathy (BKVAN) is a clinically important entity that contributes to allograft loss in kidney transplant recipients (KTRs). Mammalian target of rapamycin inhibitors…
2020 American Transplant Congress
Assessment of HEALTh LIteracy on MEdication ADheREnce and Graft Outcomes in KIdney Transplant Recipients (Hallmark)
M. Leung¹, A. Dhanda², S. Kwan³, A. Zienkiewicz³, E. Waters³, N. Wood³, L. Young³, C. Bannon³
¹Pharmacy, St. Paul's Hospital, Vancouver, BC, Canada, ²Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada, ³Nephrology, St. Paul's Hospital, Vancouver, BC, Canada
*Purpose: Upon successful kidney transplantation, many patients have difficulty adhering to their new immunosuppression medication regimens. Previous studies have established low health literacy to be…
2020 American Transplant Congress
Assessment of the Usefulness of Urine Signature to Differentiate Acute Rejection in a Prospective Kidney Transplantation Cohort
J. Seo¹, S. Jung², J. Moon², K. Jeong³, C. Kim⁴, B. Chung⁵, J. Park⁶, Y. Kim⁷, S. Lee²
¹Department of Core Research Laboratory, Medical Science Institute, Kyung Hee University Hospital at Gangdong, Seoul, Korea, Republic of, ²Department of Internal Medicine, Division of Nephrology, Kyung Hee University Hospital at Gangdong, Seoul, Korea, Republic of, ³Department of Internal Medicine, Division of Nephrology, College of Medicine, Kyung Hee University, Seoul, Korea, Republic of, ⁴Department of Internal Medicine, Division of Nephrology, Kyung-pook National University School of Medicine, Daegu, Korea, Republic of, ⁵Department of Internal Medicine, Division of Nephrology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of, ⁶Department of Internal Medicine, Sungkyunkwan University, Samsung Hospital, College of Medicine, Seoul, Korea, Republic of, ⁷Department of Internal Medicine, Division of Nephrology, Busan Paik Hospital, College of Medicine, Inje University, Busan, Korea, Republic of
*Purpose: Despite many biomarker studies in the field of transplantation, development and validation of noninvasive molecular assays to diagnose disease and monitor immune activity is…
2020 American Transplant Congress
Waiting List and Transplant Outcomes of Highly Sensitized Kidney Patients
R. Schmitz, O. K. Jawitz, S. J. Knechtle, A. M. Jackson
Department of Surgery, Duke University Medical Center, Durham, NC
*Purpose: Sensitized kidney transplant candidates represent a growing population on the waiting list. Transplantation of patients with high calculated panel reactive antibody (CPRA) can be…
2020 American Transplant Congress
Serum Osteopontin Level is Negatively Associated with Vascular Reactivity Index by Digital Thermal Monitoring in Kidney Transplant Patients
B. Hsu¹, Y. Lai¹, M. Lee²
¹Division of Nephrology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, ²Department of Surgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan
*Purpose: Osteopontin (OPN) is a potent inhibitor of mineralization and is a potent inducible inhibitor of vascular calcification. Studies in patients noted elevated levels of…
2020 American Transplant Congress
Late Intra-Patient Tacrolimus Variability Predicts De Novo Donor-Specific Antibody and Graft Loss
J. Lee¹, E. Kim¹, S. Yang², S. Kim¹, H. Choi³, B. Kim⁴, M. Ju⁵, M. Kim², S. Kim², Y. Kim², K. Huh²
¹Department of Transplantation Surgery, Severance Hospital, Seoul, Korea, Republic of, ²Department of Transplantation Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of, ³Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of, ⁴Department of Internal Medicine, Severance Hospital, Seoul, Korea, Republic of, ⁵Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of
*Purpose: Intra-patient variability (IPV) of tacrolimus level has been associated with poor outcomes after kidney transplantation. However, these findings were limited mainly to measurements early…
2020 American Transplant Congress
Effectiveness and Tolerability of Cidofovir for the Management of BK Viremia in Kidney Transplant Recipients
M. Thornberg¹, J. Hedvat¹, N. Lange¹, C. Brennan², D. Salerno¹, D. Tsapepas²
¹NewYork-Presbyterian Hospital, Department of Pharmacy, New York, NY, ²Columbia Irving University Medical Center, Department of Transplant Surgery, New York, NY
*Purpose: BK viremia (BKV) is a common complication after kidney transplantation (KT) that often leads to graft dysfunction and loss. Without consensus management guidelines and…