2022 American Transplant Congress
M1 Macrophage Polarization in Antibody-Mediated Rejection After Renal Transplantation and the Intervention Study of Iguratimod
*Purpose: After kidney transplantation, Antibody Mediated Rejection (ABMR) is the main factor affecting the long-term survival of kidney transplantation. Previous studies have confirmed that macrophage…2022 American Transplant Congress
Optimal Dose of Anti-Thymocyte Globulin to Improve Allograft and Patient Survival After Kidney Transplantation: Analysis from Korean Organ Transplantation Registry Data
Surgery, Asan Medical Center, Seoul, Seoul, Korea, Republic of
*Purpose: The optimal dose of anti-thymocyte globulin (ATG) as an induction regimen in Asian kidney recipients is unclear.*Methods: Using Korean Organ Transplantation Registry database, we…2022 American Transplant Congress
Comparison of IGG and IGM Type B Cell Receptor-Mediated MTOR Phosphorylation Signal
Division of Transplant Immunology, Division of Transplant Immunology, Tokyo, Japan
*Purpose: IgG and IgM memory B cells (mBCs) corresponding donor-specific antigen are closely involved in the activation of humoral immunity against transplanted grafts. Therefore, it…2022 American Transplant Congress
Leflunomide in Children with BK Polyomavirus Viremia After Kidney Transplant
1The Children's Hospital of Philadelphia, Philadelphia, PA, 2Yale New Haven Health, New Haven, CT
*Purpose: Studies examining the use of leflunomide in treating BK polyomavirus (BKPyV) viremia in children after kidney transplant are limited to case reports with small…2022 American Transplant Congress
Robotic-Assisted Reconstruction of the Transplant Ureter: A Minimally Invasive Option for a Rare Complication
*Purpose: Ureteric stricture are rare after kidney transplants but nonetheless this complication requires reconstruction in the majority of cases to avoid graft dysfunction and/or failure.…2022 American Transplant Congress
Lipid Metabolism Profile of Human Kidneys During Ex Vivo Normothermic Perfusion
UC Davis Medical Center, Sacramento, CA
*Purpose: The kidney is a highly metabolic organ and lipids are an important energy source. In this study, we examined the lipid profiles of discarded…2022 American Transplant Congress
Dd-cfdna Correlates With Acute Rejection In The Setting Of Bk Viremia After Kidney Transplantation
1NYU Langone Transplant Institute, New York, NY, 2CareDx, Brooklyn, NY
*Purpose: BK virus reactivation is common among kidney transplant recipients (KTRs) and is a risk factor for allograft loss. Currently, there is no clearly established…2022 American Transplant Congress
Validation of the iBox Surrogate End Point in CNI Free, Belatacept Treated Patients (BENEFIT & BENEFIT-EXT)
*Purpose: The iBox is a prognostication system for long-term kidney allograft survival, developed with mostly patients under a CNI based immunosuppression. Patients treated with a…2022 American Transplant Congress
IL-15 Signaling is Required for the Maintenance of Tissue Resident Memory T Cells in Chronic Allograft Rejection
1Starzl Transplantation Institute, Pittsburgh, PA, 2JN Biosciences, Mountain View, CA
*Purpose: Currently, no immunotherapies have been clinically proven to prevent or treat chronic rejection. IL-15 is known to support memory T cell homeostasis. However, it…2022 American Transplant Congress
Tacrolimus Exposure Estimation in Stable Kidney Transplant Recipients Using Maximum A Posteriori Bayesian Approach
*Purpose: Tacrolimus exhibits interpatient pharmacokinetic variability that impacts clinical responses and requires routine trough therapeutic drug monitoring. Tacrolimus troughs do not consistently predict area under…
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