Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Survival of ESRD Patients with an EPTS > 90% Listed for Kidney Transplant
M. S. Sampaio¹, E. Lum¹, P. Homkrailas¹, G. Danovitch¹, H. Gritsch², S. Bunnapradist¹
¹UCLA - Division of Nephrology, Los Angeles, CA, ²UCLA - Division of Urology, Los Angeles, CA
*Purpose: Mortality on the kidney transplant waitlist is high especially in candidates with a high Estimated Post Transplant Survival (EPTS) score. We examined outcomes of…
2020 American Transplant Congress
Preferences of Potential Living Kidney Donors on Strategies to Reduce Donation-Related Financial Burden
A. D. Waterman¹, O. N. Ranasinghe¹, Y. Cui², J. L. Beaumont², D. Adey³, B. Campbell⁴, F. L. Weng⁵
¹Division of Nephrology, David Geffen School of Medicine, Los Angeles, CA, ²Terasaki Research Institute, Los Angeles, CA, ³UCSF Health, San Francisco, CA, ⁴Cedars Sinai Medical Center, Los Angeles, CA, ⁵St. Barnabas Medical Center, Livingston, NJ
*Purpose: To identify the severity of financial and employment challenges present for potential living kidney donors and the value of strategies to make kidney donation…
2020 American Transplant Congress
Survey of Clinician Opinions on Use of Organ Transplants from Hepatitis C Virus Positive Donors: Identifying & Overcoming Barriers
K. Lentine¹, T. Alhamad², D. Peipert³, Y. Caliskan¹, B. Concepcion⁴, R. Forbes⁴, M. Schnitzler¹, Z. Zhang¹, S. Chang², M. Cooper⁵, R. Bloom⁶, R. Mannon⁷, D. Axelrod⁸
¹Saint Louis U, Saint Louis, MO, ²Washington U, Saint Louis, MO, ³Northwestern, Chicago, IL, ⁴Vanderbilt, Nashville, TN, ⁵Georgetown, Washington, DC, ⁶U Penn, Philadelphia, MO, ⁷UAB, Birmingham, AL, ⁸U Iowa, Iowa City, IA
*Purpose: Increasing the use of Hepatitis C Virus (HCV) viremic (Nucleic Acid Testing (NAT)+) donor organs for HCV uninfected (HCV-) patients is a potential approach…
2020 American Transplant Congress
End-Hypothermic Oxygenated Machine Perfusion after Static Cold Storage versus Static Cold Storage Alone in Kidneys from Extended Criteria Brain-Dead Donors: An International Randomized Controlled Trial
P. Husen¹, C. Boffa², I. Jochmans³, C. Krikke⁴, L. Davies², H. Hofker⁴, J. Pirenne³, R. Ploeg², A. Paul¹
¹General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany, ²Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom, ³University Hospitals Leuven, Leuven, Belgium, ⁴University Medical Center Groningen, Groningen, Netherlands
*Purpose: A prospective, randomized, single-blinded, multicenter trial comparing the effect of short-term 'in house' oxygenated hypothermic machine preservation (End-HMPO2) following static cold storage (SCS) versus…
2020 American Transplant Congress
Impact of Dialysis and Diabetes on Survival in Recipients of Combined Heart-Kidney Transplant
J. Parekh¹, H. Chau², G. Schnickel², J. Berumen², K. Mekeel²
¹University of California, San Diego, La Jolla, CA, ²Surgery, University of California, San Diego, La Jolla, CA
*Purpose: Mounting data shows a survival benefit of combined heart-kidney transplantation in patients with heart and renal failure. However, little has been done to understand…
2020 American Transplant Congress
Consequences of Turning Down High KDPI Kidney Organ Offers for Kidney Transplant Candidates
J. D. Motter, L. Liyanage, K. R. Jackson, M. G. Bowring, T. Ishaque, Y. Yu, S. Yu, J. M. Garonzik-Wang, A. B. Massie, D. L. Segev
Johns Hopkins University, Baltimore, MD
*Purpose: Kidneys with a high Kidney Donor Profile Index (KDPI, 80-100%) are frequently declined as they are associated with higher graft loss; yet, candidates that…
2020 American Transplant Congress
Pathogenesis of Polyomavirus BK Nephropathy (BKVN): Insights from Quantitative Proteomics Profiling
P. Randhawa¹, F. Fei², Y. Huang³, G. Tseng⁴, K. Xiao⁵
¹UPMC-Montefiore Hospital, Pittsburgh, PA, ²Pharmacology and Chemical Biology,, University of Pittsburgh, Pittsburgh, PA, ³Univeristy of Pittsburgh, Pittsburgh, PA, ⁴Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, ⁵Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA
*Purpose: Our current understanding of the pathogenesis of BKVN is based primarily on transcriptomics studies. However, proteins are the final effector molecules that mediate tissue…
2020 American Transplant Congress
Evaluation of an Opioid Restrictive Pain Management Initiative in Adult Kidney Transplant Recipients
S. Tischer¹, S. Maryan², L. Pacurar¹, S. Kumar¹, S. Waits¹, M. Englesbe¹, R. Sung¹, K. McMurry¹
¹Michigan Medicine - University of Michigan, Ann Arbor, MI, ²ProHealth Care, Milwaukee, WI
*Purpose: Recent national policy changes make it imperative to implement practices to reduce opioid prescribing. Despite the importance, evidence to guide opioid utilization following kidney…
2020 American Transplant Congress
Effect of Glecaprevir/Pibrentasvir on Weight-Adjusted Tacrolimus Trough/Dose Ratios in Heart and Kidney Recipients
D. Nnani¹, A. Campbell¹, M. Ajaimy², S. R. Patel³, O. Saeed³, D. J. Goldstein⁴, J. Graham⁵, U. P. Jorde³
¹Pharmacy, Montefiore Medical Center, Bronx, NY, ²Medicine, Montefiore Medical Center, Bronx, NY, ³Division of Cardiology, Department of Medicine, Montefiore Medical Center, Bronx, NY, ⁴Cardiothoracic Surgery, Montefiore Medical Center, Bronx, NY, ⁵Surgery, Montefiore Medical Center, Bronx, NY
*Purpose: An innovative strategy to meet the demands of patients requiring heart or kidney transplantation is the acceptance of hepatitis C viremic organs. Direct acting…
2020 American Transplant Congress
Epitope Analysis of Complement-Binding De Novo Donor-Specific HLA Class II Antibody
K. Yamanaka, M. Hashimoto, T. Kinoshita, Y. Fujita, S. Matsumura, T. Imanaka, A. Taniguchi, T. Yoshida, H. Kishikawa
Department of Kidney Transplantation Center, Hyogo Prefectural Nishinomiya Hospital, Nishinomiya, Hyogo, Japan
*Purpose: Patients with de novo donor specific antibody (dnDSA) after kidney transplantation have a poorer prognosis than patients without dnDSA. Meanwhile, patients with dnDSA do…