Articles tagged "Kidney transplantation"

2020 American Transplant Congress
BK Viremia: A Double Edged Sword – The Impact of Immunosuppression Reduction on Allograft Rejection
A. Szczepanik¹, A. Bixby¹, C. Burrelli¹, A. Padiyar², T. Srinivas², K. Chavin³
¹Pharmacy, University Cleveland Medical Center, Cleveland, OH, ²Nephrology, University Cleveland Medical Center, Cleveland, OH, ³Surgery, University Cleveland Medical Center, Cleveland, OH
*Purpose: BK viremia (BKV) increases the risk of renal allograft loss following transplant. Guidelines recommend reduction of immunosuppression (IS) after BKV diagnosis, however, the ideal…
2020 American Transplant Congress
Perceived Barriers Are Associated with Immunosuppressive Medication Adherence among Japanese Kidney Transplant Recipients: A Cross-Sectional Study
M. Takada¹, K. Oda², T. Kaitani², M. Fujii²
¹The Graduate School of Nursing, Sapporo City University, Sapporo, Japan, ²School of Nursing, Sapporo City University, Sapporo, Japan
*Purpose: Nonadherence to immunosuppressive medication after kidney transplantation is associated with a high risk of acute rejection and allograft loss. This study aimed to investigate…
2020 American Transplant Congress
Characterization of an Integrative Prognostic Score for US Patients Taken from the DART Study
J. Bromberg¹, R. Bloom², P. Sood³
¹University of Maryland, Baltimore, MD, ²Penn Medicine, Philadelphia, PA, ³University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: iBox is a validated cloud-based software as a service (SaaS) algorithm that provides a predictive analysis of the post-transplant patient, quantifying the risk of…
2020 American Transplant Congress
The Time is Now: Improving Waiting Times in Minority Populations
L. Mendez-Castaner, L. Preczewski, M. Muldoon, A. Harshman, M. Goble, G. Guerra
Miami Transplant Institute, Miami, FL
*Purpose: A significant limiting factor to transplantation resides on waiting time based on blood type. Historically candidates in blood groups B and O experience higher…
2020 American Transplant Congress
Safety and Efficacy of Direct-Acting Oral Anticoagulants versus Warfarin in Kidney Transplant Recipients
A. L. Bixby¹, S. A. Shaikh², A. S. Naik³, L. Cotiguala³, K. McMurry³, M. D. Samaniego-Picota⁴, V. D. Marshall⁵, J. M. Park³
¹University Hospitals Cleveland Medical Center, Cleveland, OH, ²Keck Medical Center of USC, University of Southern California, Los Angeles, CA, ³Michigan Medicine, Ann Arbor, MI, ⁴Henry Ford Transplant Institute, Detroit, MI, ⁵University of Michigan College of Pharmacy, Ann Arbor, MI
*Purpose: Safety and efficacy of direct-acting oral anticoagulants (DOACs) have not been well studied in solid organ transplant. The purpose of our study was to…
2020 American Transplant Congress
Donor-Specific Antibody Test as a Screening Tool for Stable Long-Term Kidney Transplant Recipients
M. Mohamed¹, L. Hidalgo², S. Parajuli¹, N. Garg¹, F. Aziz¹, K. Swanson¹, E. Jochaim¹, D. Mandelbrot¹, A. Djamali¹, B. Astor¹
¹Department of Nephrology, Madison, WI, ²Department of Surgery, Madison, WI
*Purpose: Donor-specific antibody (DSA) is an established biomarker predicting antibody mediated rejection (AMR), but at substantial cost. The utility of DSA test as a screening…
2020 American Transplant Congress
Impact of Depleting Induction Agents on BK Virus and Polyomavirus Associated Nephropathy
J. Clark¹, A. Barlow¹, A. Haririan²
¹University of Maryland Medical Center, Baltimore, MD, ²University of Maryland School of Medicine, Baltimore, MD
*Purpose: Polyomavirus associated nephropathy (PVAN) is an opportunistic infection associated with graft loss and rejection. Due to limited treatment options, identifying kidney transplant recipients at…
2020 American Transplant Congress
Determinants of Kidney Transplant Candidates’ Willingness to Accept Deceased Donor Organ Intervention Research: A Conjoint Analysis
E. Gordon¹, P. Reese², J. Lee¹, L. Krishnamurthi¹, R. Veatch³, R. Knight⁴, P. T. Conway⁴, S. Dunn⁵, P. Abt²
¹Northwestern University, Chicago, IL, ²University of Pennsylvania, Philadelphia, PA, ³Georgetown University, Washington, DC, ⁴American Association of Kidney Diseases, Tampa, FL, ⁵Organ Alliance, Denver, CO
*Purpose: Deceased donor organ intervention research (“intervention research”) aims to increase organ quality and quantity for transplantation by protecting against organ injury and enhancing functionality.…
2020 American Transplant Congress
Introduction of Preemptive Pharmacogenomic Testing in Kidney Transplant Recipients: Early Evaluation of the Clinical Impact of Genomic Guided Tacrolimus Dosing
G. Girone¹, V. Do¹, K. Belfield¹, R. Pulk¹, E. Cohen¹, E. Marin²
¹Department of Pharmacy, Yale New Haven Hospital, New Haven, CT, ²Department of Nephrology, Yale School of Medicine, New Haven, CT
*Purpose: Tacrolimus is widely accepted as the mainstay of immunosuppression in solid organ transplant. Inherited differences in CYP3A activity are known to contribute to dosing…
2020 American Transplant Congress
Impact of Recipient Obesity on Kidney Transplantation Outcome: A Retrospective Cohort Study with a Matched Comparison
A. Buemi¹, L. Romero¹, F. Zech², T. Darius¹, M. De Meyer¹, A. Devresse³, N. Kanaan³, E. Goffin³, M. Mourad¹
¹Surgery, Cliniques Universitaires Saint Luc, Bruxelles, Belgium, ²Internal Medicine, Cliniques Universitaires Saint Luc, Bruxelles, Belgium, ³Nephrology, Cliniques Universitaires Saint Luc, Bruxelles, Belgium
*Purpose: The benefit of renal transplantation in obese patients is changeling. This study was undertaken to determine the effect of recipient obesity on patient and…