Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Inequitable Access to Living Donor Kidney Transplantation in Black and Asian Minority Ethnic Groups in the UK: A Single Centre Cross-Sectional Cohort Study
A. Cronin, K. Sran, R. Gokmen, A. Copley, L. Silas, R. Zakri
Guy's and St. Thomas' Hospital, London, United Kingdom
*Purpose: Black, Asian and Minority Ethnic (BAME) communities constitute 11% of the UK population, yet represent 31% of the national kidney transplant waiting list. Moreover,…
2020 American Transplant Congress
Association between Sarcopenia and Nutritional Factors in Kidney Transplant Recipients
A. Kosoku¹, J. Uchida¹, T. Ishihara², T. Iwai¹, H. Shimada¹, K. Kabei¹, S. Nishide¹, T. Naganuma¹, T. Nakatani¹
¹Urology, Osaka City University Graduate School of Medicine, Osaka, Japan, ²Innovative and Clinical Research Promotion Center, Gifu University Hospital, Gihu, Japan
*Purpose: Malnutrition is an important risk factor for the development of sarcopenia. Several methods are used for the assessment of nutritional status including serum albumin…
2020 American Transplant Congress
Impact of PD1, PDL1 Gene Polymorphisms on Allo-Immune Responses after Kidney Transplantation
H. Yamane, Y. Tanaka, M. Ohira, H. Tahara, K. Ide, H. Ohdan
Hiroshima University, Hiroshima, Japan
*Purpose: The programmed death (PD)-1/PD-1 ligands (PD-Ls) pathway, a member of the B7/CD28 family, triggers an immune checkpoint resulting in inhibition of T cells. Several…
2020 American Transplant Congress
Prevalence of Frailty and Cognitive Impairment at Time of Kidney Transplant Evaluation
J. Klein, A. Jurgensen, M. Gupta, N. Herrera, A. Gupta, D. Cibrik
Internal Medicine, Division of Nephrology, University of Kansas Medical Center, Kansas City, KS
*Purpose: Frailty is highly prevalent in kidney disease, with prevalence estimates as high as 73% in patients at the time of dialysis initiation compared to…
2020 American Transplant Congress
Belatacept-Based Regimens: Induction and Recipient Gender Influence Outcomes
N. Wilson¹, A. R. Shields², A. Wiseman³, A. L. Christianson¹, S. Tremblay¹, D. Kaufman⁴, J. P. Leone⁵, A. J. Matas⁶, P. West-Thielke⁷, R. R. Alloway¹, E. S. Woodle¹
¹U Cincinnati, Cincinnati, OH, ²The Christ Hospital, Cincinnati, OH, ³U Colorado, Denver, CO, ⁴U Wisconsin, Madison, WI, ⁵Tampa General, Tampa, FL, ⁶U Minnesota, Minneapolis, MN, ⁷U Illinois Chicago, Chicago, IL
*Purpose: Renal function and adverse event profiles in kidney transplant (KTx) patients under belatacept (BELA) based immunosuppression are significantly improved over calcineurin inhibitors, however BELA…
2020 American Transplant Congress
Variability in Educational Content about Kidney Paired Donation at 68 National Kidney Registry-Affiliated Centers
A. D. Waterman¹, O. N. Ranasinghe¹, E. H. Wood¹, J. L. Beaumont², S. McGuire³, K. Miller⁴, V. Chipman⁵, J. Sinacore⁶, M. Cooper⁷
¹Division of Nephrology, David Geffen School of Medicine, Los Angeles, CA, ²Terasaki Research Institute, Los Angeles, CA, ³UCLA Kidney and Pancreas Transplant Programs, Los Angeles, CA, ⁴UW Health, Madison, WI, ⁵UCSF Medical Center, San Francisco, CA, ⁶National Kidney Registry, Babylon, NY, ⁷Medstar Georgetown Transplant Institute, Washington, DC
*Purpose: Equipping patients and donors with in-depth information about kidney paired donation (KPD) processes, risks, benefits, and protections is necessary for informed decision-making and comfort.…
2020 American Transplant Congress
Predicting Kidney Allograft Discard: The Kidney Discard Risk Index
M. B. Price, M. Joshi, T. Zhang, J. Vierling, T. Galvan, R. Cotton, C. O'Mahony, J. Goss, A. Rana
Michael E. DeBakey Department of Surgery, Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX
*Purpose: The disparity between the supply and demand for kidney allografts is exacerbated by an 18.9% discard rate. It is our aim to determine predictors…
2020 American Transplant Congress
Comparative Review of Adult Kidney Transplant Medicare Cost Report Reimbursement in U. S. Transplant Hospitals
E. Zavala¹, J. Rogers², S. Karp¹
¹Vanderbilt University Medical Center, Nashville, TN, ²Transplant Management Group, San Diego, CA
*Purpose: Medicare organ acquisition reimbursement (MOAR) from the Medicare Cost Report (MCR) includes but is not limited to costs associated with candidate evaluation, maintenance on…
2020 American Transplant Congress
Single Cell Profiling of PBMC Identifies Immune Populations Associated with High Risk of Early Acute Rejection
W. Zhang, S. Farouk, Z. Sun, W. Huang, Z. Yi, J. Fu, C. Wei, M. Fribourg-Casajuana, C. He, P. Cravedi, B. Murphy
Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Our previous transcriptomic analysis of pre-transplant peripheral blood revealed a 23-gene set predictive of early acute rejection (EAR) post kidney transplant (JCI Insight, 2019).…
2020 American Transplant Congress
Activation of the ICOS/ICOS-Ligand Pathway in Antibody-Mediated Kidney Graft Rejection
V. Cantaluppi¹, G. Merlotti¹, M. Quaglia¹, G. Rosso¹, N. Clemente¹, G. Cappellano¹, A. Chiocchetti¹, G. Castellano², U. Dianzani¹, G. Camussi³
¹Nephrology and Kidney Transplantation Unit, University of Piemonte Orientale (UPO), Novara, Italy, ²Nephrology, Dialysis and Kidney Transplantation Unit, University of Foggia, Foggia, Italy, ³Department of Medical Sciences, University of Torino, Torino, Italy
*Purpose: The costimulatory pathway ICOS/ICOS-Ligand may represent a new therapeutic target in antibody-mediated rejection (ABMR), the major cause of long term kidney graft failure. The…