Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Improved Outcomes Over the Past 13 Years in HIV Positive Kidney Transplant Recipients-A Single Center Experience
A. Mattiazzi¹, J. F. Camargo², S. Anjan², M. I. Morris², L. Abbo², J. Simkins², Y. Natori², K. Aoke³, A. Zilli³, R. Thurston³, M. Muldoon³, L. Preczewski³, L. J. Chen⁴, G. W. Burke⁴, G. Ciancio⁴, G. Guerra¹
¹Medicine. Division of Nephrology, University of Miami/Miami Transplant Institute, Miami, FL, ²Medine. Division of Infectious Disease, University of Miami/Miami Transplant Institute, Miami, FL, ³Miami Transplant Institute, Miami, FL, ⁴Surgery, University of Miami/Miami Transplant Institute, Miami, FL
*Purpose: Kidney transplantation in HIV positive recipients (HIV+) is the treatment of choice for renal failure in patients (P) who maintain CD4+ counts ≥ 200/mm3and…
2020 American Transplant Congress
Impact of Extended- versus Immediate-Release Tacrolimus on One-Year Development of De Novo DSA and Chronic Immune Activation in Kidney Transplantation (ASTOUND Study)
A. Wiseman¹, D. Kaufman², A. Patel³, D. Wojciechowski⁴, A. Tambur⁵, J. Kim⁶, J. Schwartz⁶
¹University of Colorado Hospital, Aurora, CO, ²University of Wisconsin, Madison, WI, ³Henry Ford Hospital, Detroit, MS, ⁴Massachusetts General Hospital, Boston, MA, ⁵Northwestern University, Chicago, IL, ⁶Astellas Pharma Global Development, Northbrook, IL
*Purpose: To compare, using an adaptive study design, the 1-year incidence of a novel two-part composite endpoint consisting of de novo donor-specific antibody (dnDSA) formation…
2020 American Transplant Congress
Glomerular Filtration Rate Based on Cystatin C Provides the Best Prediction of Cardiovascular Events and Mortality Compared to Measured GFR and Creatinine Based GFR in Kidney Transplant Recipients
L. Galapia¹, J. Lieske², A. Rule², H. Amer², N. Zhang¹, D. Butterfield¹, M. Keddis¹
¹Mayo Clinic, Scottsdale, AZ, ²Mayo Clinic, Rochester, MN
*Purpose: GFR estimated by cystatin C (CysC) is a better predictor of cardiovascular (CV) events and mortality compared to eGFR by creatinine (Cr) in native…
2020 American Transplant Congress
Waitlist-Conditioned Transplant Rate is Not an Appropriate Metric for Benchmarking Access to Kidney Transplantation
D. Anderson, H. Qu, P. MacLennan, M. Mustian, R. Reed, A. C. Kale, B. Orandi, B. Shelton, V. Kumar, J. Locke, M. Hanaway
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Transplant rate is used as a primary metric of center performance as reported by the SRTR. However, the calculation of transplant rate can be…
2020 American Transplant Congress
Molecular Diagnosis and Risk Prediction in BK Virus Nephropathy: Discovery and Multicenter Validation of Novel Intragraft Gene Expression Signatures
B. Adam¹, Z. Kikic², Y. Bouatou³, J. Gueguen³, B. Robin³, G. Reid¹, H. Regele², M. Rabant³, A. Loupy³, M. Mengel¹
¹University of Alberta, Edmonton, AB, Canada, ²Medical University of Vienna, Vienna, Austria, ³Paris Transplant Group, Paris, France
*Purpose: Novel tools are needed to improve diagnosis and risk prediction in BK virus nephropathy (BKVN). This study aimed to assess the utility of intragraft…
2020 American Transplant Congress
Predictive Validity of Functional Status on Mortality in Adult Kidney Transplant Recipients
N. Chu, Z. Shi, D. Segev, M. McAdams Demarco
Johns Hopkins, Baltimore, MD
*Purpose: Frailty and disabilities, though not routinely measured, are highly prevalent in kidney transplant (KT) recipients and predict poor post-transplant outcomes. The Karnofsky Performance Scale…
2020 American Transplant Congress
Mycophenolic Acid Exposure in Young, Middle Age and Older Stable Renal Transplant Recipients
K. Tornatore¹, K. Attwood², R. Venuto³
¹School of Pharmacy; University at Buffalo, Williamsville Buffalo, NY, ²School of Pharmacy; University at Buffalo Department of Biostatistics; Roswell Park Comprehensive Cancer Center, Buffalo, NY, ³School of Medicine; University at Buffalo, Buffalo, NY
*Purpose: Mycophenolic acid (MPA) is an essential drug in maintenance immunosuppressive regimens. In spite of increased kidney transplants in the elderly, limited pharmacokinetic investigations comparing…
2020 American Transplant Congress
The Clinical Usefulness of Preformed C1q-Binding Donor-Specific Antibodies in Kidney Transplantation
S. Lee, E. Ko, B. Chung, C. Yang
Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of
*Purpose: The anti-human leukocyte antigen (HLA) antibodies are well known for risk factor of rejection or allograft loss. Additionally, de novo complement component 1q-binding donor-specific…
2020 American Transplant Congress
Are Living Donor Offers a Missed Opportunity? A Social Network Analysis of End-Stage Renal Disease Patients
A. Gillespie¹, J. Cappiello², R. L. Brown¹, H. M. Gardiner², E. L. Fink³, P. P. Reese⁴, C. Gadegbeku⁵, Z. Obradovic⁶
¹Lewis Katz School of Medicine at Temple University, Bala Cynwyd, PA, ²Temple University College of Public Health, Philadelphia, PA, ³Lew Klein School of Media and Communication Temple University, Philadelphia, PA, ⁴Perelman School of Medicine University of Pennsylvania, Philadelphia, PA, ⁵Lewis Katz School of Medicine at Temple University, Philadelphia, PA, ⁶Center for Data Analytics and Biomedical Informatics at Temple University, Philadelphia, PA
*Purpose: Increasing the rates of living donor kidney transplantation is a priority, yet not much is known about the members of an end-stage renal disease…
2020 American Transplant Congress
Surgical Nephrectomy of the Native Kidneys: Greater Cardiovascular Benefit in Renal Transplant Recipients?
J. Sleiman, G. Soler Pujol, L. Brukman, G. Laham, M. Schiavone, C. Castellaro, C. Diaz
Nephrology, CEMIC, Caba, Argentina
*Purpose: The survival of the graft in patients (px) with renal transplantation (RT) depends on multiple cardiovascular (CV) factors. With CKD progression, sympathetic activity increases,…