Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Native Nephrectomy at the Time of Transplant: Risk for Adrenal Injury?
T. Salinas¹, D. Dadhania¹, J. Lee¹, M. Aull¹, S. Kapur², M. Lubetzky¹
¹Nephrology, NY Presbyterian- Weill Cornell, New York, NY, ²Surgery, NY Presbyterian- Weill Cornell, New York, NY
*Purpose: Living donor studies have demonstrated that native nephrectomy (Nx) is associated with transient but symptomatic loss of adrenal function. Although surgical complications from simultaneous…
2020 American Transplant Congress
Microarray and RNA-Seq Analysis of Rejection in Formalin-Fixed Paraffin-Embedded (FFPE) Biopsies: Comparing FFPE to Conventionally Stabilized (RNAlater Solution) Biopsies
P. Halloran¹, K. Famulski¹, J. Reeve¹, J. Huang², N. Alexandrov²
¹University of Alberta, Edmonton, AB, Canada, ²R&D Transplant Diagnostics Division, Thermo Fisher Scientific, Los Angeles, CA
*Purpose: Molecular understanding of organ transplant biopsies requires genome-wide measurements and molecular classifiers. To assess potential of performing molecular diagnostics on formalin-fixed paraffin-embedded (FFPE) biopsies,…
2020 American Transplant Congress
Establishing an Induction Protocol for Long-Term Multilineage Mixed Chimerism in Rhesus Macaques
K. Bruestle¹, H. Sakai¹, F. Fredriksson¹, B. Piegari¹, D. Ekanayake-Alper¹, A. McLuckie², R. Ober², J. Weiner¹, A. Iuga³, S. M. Coley³, M. Sykes¹, A. Griesemer¹
¹Columbia Center for Translational Immunology, Columbia University, New York City, NY, ²Institute for Comparative Medicine, Columbia University, New York City, NY, ³Department of Pathology and Cell Biology, Columbia University, New York City, NY
*Purpose: Mixed chimerism (MC) induction via non-myeloablative conditioning and bone marrow transplantation (BMT) induces tolerance to solid organs. Our standard MC induction protocol in cynomologous…
2020 American Transplant Congress
One Organ Procurement Organization Coordinates 43% of All Uncontrolled Donation after Circulatory Determination of Death Donors Recovered in the United States Over 24 Years
R. D. Hasz, S. M. West, H. M. Nathan
Gift of Life Donor Program, Philadelphia, PA
*Purpose: An IOM report published in 2006 estimated that 22,000 potential uncontrolled Donation after Circulatory Determination of Death (uDCDD) donors die each year in the…
2020 American Transplant Congress
Reverse Epidemiology and the Obesity Paradox for Patients with Chronic Kidney Disease
R. A. Choudhury¹, D. Yoeli¹, H. B. Moore¹, H. Yaffe¹, G. Hoeltzel², K. R. Dumon³, N. N. Williams³, P. L. Abt⁴, K. D. Conzen¹, T. L. Nydam¹
¹Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, ²Thomas Jefferson University Hospital, Philadelphia, PA, ³University of Pennsylvania Hospital, Philadelphia, PA, ⁴Department of Surgery- Division of Transplantation Surgery, University of Pennsylvania Hospital, Philadelphia, PA
*Purpose: Obesity has been associated with both increased progression of chronic kidney disease as well as with a paradoxical improvement in survival among ESRD patients…
2020 American Transplant Congress
Validation of Prognostic Index for Allograft Outcome in Kidney Transplant Recipients with Transplant Glomerulopathy
M. Talwar¹, V. Balaraman¹, A. Bhalla¹, O. Cseprekal², M. Yazawa¹, P. S. Podila³, A. Azhar¹, L. N. Cossey⁴, J. D. Eason¹, M. Z. Molnar¹
¹James D. Eason Transplant Institute, Methodist University Hospital, Memphis, TN, ²Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary, ³Faith & Health Division, Methodist Le Bonheur Healthcare, Memphis, TN, ⁴Arkanalabs, Little Rock, AR
*Purpose: Kidney transplant recipients with Transplant Glomerulopathy (TG) have very poor allograft survival compared to those without TG. The objective of this research was to…
2020 American Transplant Congress
Long Term Outcomes of Kidney Transplantation in Patients with AL-Amyloidosis – The Mayo Clinic Experience
A. Bentall¹, C. Heybali², J. Wen³, A. Hatem¹, C. A. Schinstock¹, E. Lorenz¹, M. El Ters¹, M. Mai⁴, H. Khamash⁵, D. Murray⁶, M. D. Stegall⁷, F. G. Cosio¹, M. P. Alexander⁶, N. Leung¹
¹Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ²School of Medicine, Dokuz Eylul University, Izmir, Turkey, ³National Clinical Research Center of Kidney Disease, Jinling Hospital, Nanjing, China, ⁴Division of Nephrology and Hypertension, Mayo Clinic, Jacksonville, FL, ⁵Division of Nephrology and Hypertension, Mayo Clinic, Scottsdale, AZ, ⁶Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, ⁷Department of Transplant Surgery, Mayo Clinic, Rochester, MN
*Purpose: New clone-directed therapies and better definition of hematological response criteria allows assessment of post-kidney transplantation outcomes in patients with light-chain (AL) amyloidosis*Methods: Patients with…
2020 American Transplant Congress
Maternal Peripartum Complications in Solid Organ Transplantation
R. X. Wang¹, G. S. Lee-Riddle², D. O. Walls³, D. S. Goldberg⁴, P. L. Abt²
¹Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, ²Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, ³Department of Surgery, Robert Wood Johnson University Hospital, New Brunswick, NJ, ⁴Department of Medicine, University of Miami Miller School of Medicine, Miami, FL
*Purpose: Previous studies examining pregnancy related complications after solid organ transplantation (SOT) primarily relied on voluntary registries and meta-analyses. Herein, we investigated maternal delivery outcomes…
2020 American Transplant Congress
Incidence of Cytomegalovirus Infection in Deceased Donor Kidney Transplantation from Hepatitis-C Antibody Positive Donors to Hepatitis-C Antibody Negative Recipients: A National Registry Analysis
M. Yazawa¹, T. Fülöp², O. Cseprekal³, M. Talwar¹, V. Balaraman¹, A. Bhalla¹, A. Azhar¹, C. P. Kovesdy⁴, J. D. Eason¹, M. Z. Molnar¹
¹James D. Eason Transplant Institute, Methodist University Hospital, Memphis, TN, ²Division of Nephrology, Department of Medicine, Medical University of South Carolina, South Carolina, SC, ³Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary, ⁴Division of Nephrology, Department of Medicine, University of Tennessee Health Science Center, Memphis, TN
*Purpose: Deceased donor kidney transplantation (KT) from hepatitis C (HCV) infected donors into HCV uninfected recipients (HCV D+/R-) will be the standard of care in…
2020 American Transplant Congress
Factors Influencing Emergency Department Utilization and Hospital Re-Admissions in an Adult Urban Renal Transplant Population
A. Lichvar¹, A. Patel², R. Petzel Gimbar¹, D. Pierce¹, I. Tzvetanov¹, E. Benedetti¹, M. Campara¹
¹University of Illinois at Chicago, Chicago, IL, ²University of Chicago Medicine, Chicago, IL
*Purpose: Emergency department (ED) visits and hospital re-admissions increase morbidity, decrease quality of life, and increase healthcare costs after renal transplant (RT). The purpose of…