Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Pegloticase for Uncontrolled Gout in Kidney Transplant Recipients: Provisional Data Report of a Multicenter, Open-Label, Efficacy and Safety Study
A. Abdellatif¹, L. Zhao², K. Cherny², B. Marder², J. D. Scandling³, K. Saag⁴
¹Division of Nephrology, Baylor College of Medicine, Houston, TX, ²Horizon Therapeutics PLC, Deerfield, IL, ³Division of Nephrology, Stanford School of Medicine, Stanford, CA, ⁴Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL
*Purpose: Gout in kidney transplant (KT) recipients can be severe and particularly challenging to manage. Pegloticase co-therapy with immunomodulators improved urate lowering therapy (ULT) response…
2022 American Transplant Congress
Bisphosphonates for Fracture Prevention in Kidney Transplant Recipients
J. Kahwaji¹, S. Yang², J. Sim³
¹Nephrology/Transplant, Kaiser Los Angeles Medical Center, Los Angeles, CA, ²Research and Evaluation, Kaiser-Permanente, Pasadena, CA, ³Nephrology, Kaiser Los Angeles Medical Center, Los Angeles, CA
*Purpose: Kidney transplant recipients are at increased risk of fracture, however bisphosphonate use has not be shown to lower fracture risk in this population. We…
2022 American Transplant Congress
Hard to Place Dual Kidney Transplantation (HTPDKT): A Viable Option Despite Prolonged Cold Ischemia
R. Plews¹, E. Siskind², M. Laftavi², E. Shipman³, S. Shah², D. Conti⁴, A. Adekile², S. Nijim², S. K. Patel²
¹Albany Medical College, Albany, NY, ²Center for Transplantation, University Medical Center of Southern Nevada, Las Vegas, NV, ³Nevada Donor Network, Las Vegas, NV, ⁴Albany Medical Center, Albany, NY
*Purpose: Less than perfect kidneys are often difficult to place in the current kidney allocation system. The kidneys have to travel extended distances , increasing…
2022 American Transplant Congress
Presence of AT1R Antibody Pre-Transplant Does Not Correlate with Rejection in a Large Pediatric Kidney Transplant Cohort
K. Hitchman¹, P. K. Shah¹, D. Fritze¹, R. Hinojosa², D. Ranch¹
¹University Health Transplant Institute, San Antonio, TX, ²Pharmacy, University Health Transplant Institute, San Antonio, TX
*Purpose: Describe correlations between pre-transplant (PreTXP) presence of anti-angiotensin II receptor type 1 antibodies (AT1RAb) and post-transplant (PostTXP) outcomes in a pediatric kidney transplant (PKT)…
2022 American Transplant Congress
Sensitization and BK Viremia; Risk Following Sub-Clinical COVID-19 Infection in Pediatric Kidney Transplant Recipients
E. Benz¹, M. Chandran², J. Chuita¹, K. McKinnon¹, A. Sikora¹, M. Bock¹, E. Blanchette¹
¹Children's Hospital Colorado, Aurora, CO, ²University of North Carolina, Chapel Hill, NC
*Purpose: In contrast to high morbidity and mortality of COVID-19 infection (COVIDi) in adult kidney transplant (KT) recipients, these sequelae appear to be muted in…
2022 American Transplant Congress
Outcomes After Deceased Donor Kidney Transplantation Utilizing Kidney Allografts with Marginal Perfusion Parameters: A Single-Center Experience
P. N. Chotai¹, A. Logan², F. Siddiqui³, A. Schenk⁴, G. Bumgardner⁵, G. L. Brock², A. El-Hinnawi⁵, A. Rajab⁶, K. Washburn⁷, N. Singh²
¹Division of Transplantation, Department of General Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, ²The Ohio State University Wexner Medical Center, Columbus, OH, ³Ohio State University, Bloomfield, NJ, ⁴Ohio State University Wexner Medical Center, Bexley, OH, ⁵Ohio State University, Columbus, OH, ⁶Ohio State University Wexner Medical Center, Columbus, OH, ⁷The Ohio State University, Columbus, OH
*Purpose: To study outcomes of deceased donor kidney transplantation (DDKT) in recipients of kidney allografts with poor perfusion parameters.*Methods: This is a retrospective, single center…
2022 American Transplant Congress
Longevity Matching for Living Donor Renal Transplantation
S. Karhadkar¹, J. Dawes¹, K. Wirshup¹, J. Kolansky¹, A. Gregor¹, A. Diamond², A. DiCarlo¹
¹Temple University Hospital, Philadelphia, PA, ²-, Garnet Valley, PA
*Purpose: Living donor kidney transplantation (LDKT) continues to become a more prevalent treatment method for ESRD and is known to increase both organ availability and…
2022 American Transplant Congress
Kidney Transplantation in Patients Postradical Prostatectomy
S. Karhadkar, K. Wirshup, J. Kolansky, A. Gregor, J. Dawes, A. DiCarlo
Temple University Hospital, Philadelphia, PA
*Purpose: The population of the United States is aging. By the year 2050 those over 65 years of age are projected to make up 20.2%…
2022 American Transplant Congress
Changes in Diastolic Function and Cardiac Geometry After Pediatric Kidney Transplant: A Longitudinal Study
K. Sgambat¹, S. Clauss², A. Moudgil¹
¹Nephrology, Children's National Hospital, Washington DC, DC, ²Cardiology, Children's National Hospital, Washington DC, DC
*Purpose: Kidney transplant recipients are at increased risk for cardiovascular disease but systolic function is often preserved and may not reveal cardiac dysfunction until it…
2022 American Transplant Congress
Ex Vivo Modification of Vascular Allografts Using Immunosuppressive and Anti-Inflammatory Polymers Prevent Rejection via Localized Immunosuppression
H. D. Luo¹, E. M. Siren¹, W. Enns², L. Sim¹, C. Du¹, S. G. Withers¹, J. Choy³, J. N. Kizhakkedathu¹
¹The University of British Columbia, Vancouver, BC, Canada, ²Simon Fraser University, Burnaby, BC, Canada, ³Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada
*Purpose: Classical immunosuppressants lead to systemic immune shutdown, though necessary to mediate transplant rejection, it may lead to various complications. To reduce off-target immunosuppression while…