Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Impact of Early Calcineurin-Inhibitor Conversion to Belatacept on Renal Allograft Function in a Steroid-Free Maintenance Regimen: Results from a Randomized Controlled Study
I. Tawhari¹, P. Hallak¹, S. Hartzell², V. Mas³, P. Cravedi², J. Leventhal¹, J. Ansari¹, L. Gallon¹
¹Northwestern University, Chicago, IL, ²Mount Sinai, New York, NY, ³University of Maryland, Baltimore, MD
*Purpose: Belatacept (Bela) was developed to minimize nephrotoxicity and cardiovascular risk associated with Calcineurin inhibitors (CNIs). Early steroid withdrawal (ESW) and simultaneous CNI avoidance (CNIA)…
2022 American Transplant Congress
Impact of End-of-Chain Kidney Allocation on Access to Kidney Transplantation of Minority Patients: Implications for Reducing Disparities
J. Wade¹, K. Rancourt², A. Anane², A. Landeen², J. U. Singh³, X. Ye³, J. Tremaglio³, Z. Ebcioglu³, R. Kent³, B. Emmanuel⁴, G. Morgan⁴, O. K. Serrano⁴, W. Dar⁴
¹Department of Surgery, Surgical Research Program, Hartford Hospital, Hartford, CT, ²Hartford Hospital Transplant & Comprehensive Liver Center, Hartford, CT, ³Department of Medicine, Hartford Hospital Transplant & Comprehensive Liver Center, Hartford, CT, ⁴Department of Surgery, Hartford Hospital Transplant & Comprehensive Liver Center, Hartford, CT
*Purpose: Disparities in access to kidney transplantation (KT) among non-White patients is well-known, especially as it relates to living donor kidney transplantation (LDKT). We investigated…
2022 American Transplant Congress
Trends in Donor Derived Cell Free DNA Before and After Cellular and Antibody Mediated Rejection
K. Guo¹, J. Friedewald¹, C. Rebello¹, B. Kinsella¹, S. Park², L. Zhao¹
¹Northwestern University, Chicago, IL, ²Transplant nephrology, Northwestern University, Chicago, IL
*Purpose: The TRAC dd-cfDNA test was developed to detect acute kidney transplant rejection but can also detect subclinical rejection with improved performance in antibody-mediated rejection…
2022 American Transplant Congress
A Three-gene Peripheral Blood Potential Diagnosis Signature Associated With Autophagy For Antibody-mediated Rejection In Renal Transplantation
Y. Wang, Y. Xu, H. Zhang, X. Hu
Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
*Purpose: Antibody-mediated rejection (AMR) is emerging as a major cause of graft loss in renal transplantation. Nowadays, non-invasive diagnosis of AMR with high accuracy is…
2022 American Transplant Congress
Lucas Device Assisted Uncontrolled Dcd Kidney Transplantation – A Feasible but Underutilized Option in the United States
S. Nagaraju, S. Vaishnav, R. Savilla, M. Moore, J. B. Africa
Renal Transplant, Charleston Area Medical Center, Charleston, WV
*Purpose: Uncontrolled DCD (uDCD) procurement involves either normo-thermic or hypothermic regional perfusion to reduce ischemic injury. We report a series of successful kidney transplant utilizing…
2022 American Transplant Congress
Single Kidney Transplantation from Small Pediatric Donors Aged < 2 Years Into Pediatric Recipients: A Retrospective Single-Center Cohort Study
Q. Zhang, M. Huang, J. Li, W. Wu, H. Zhang, C. Wu, Q. Fu, P. Gao, L. Ling, W. Chen, B. Xu, X. Su, L. Liu, C. Wang
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China
*Purpose: Kidneys from small pediatric donors (aged < 2 years, SPD) are underutilized. Concerns regarding potentially inferior outcomes hinder the use in pediatric recipients, especially…
2022 American Transplant Congress
Long-Term Clinical Outcomes in ABO Incompatible Kidney Transplantation in Patients with High Baseline Anti-A/B Antibody Titer
S. Eum¹, H. Lee¹, E. Ko¹, H. Yoon², S. Shin², C. Yang¹, B. Chung¹
¹Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, Seoul, Korea, Republic of, ²Division of Nephrology, Department of Internal Medicine, Incheon St. Mary's Hospital, Incheon, Korea, Republic of
*Purpose: ABO incompatible (ABOi) kidney transplantation (KT) has been considered to overcome donor shortage. We investigated the long-term clinical outcomes in ABOi KT in patients…
2022 American Transplant Congress
Novel Biopsy-Based Clinical Phenotype Clustering to Predict Kidney Transplant Outcomes
A. Ahmed¹, L. Allegretti², C. Rebello³, B. Kinsella³, K. Guo³, S. Park⁴, J. Friedewald³
¹Chicago Medical School at Rosalind Franklin University, Chicago, IL, ²University of Wisconsin, Madison, WI, ³Northwestern University, Chicago, IL, ⁴Transplant Nephrology, Northwestern University, Chicago, IL
*Purpose: The purpose of this study was to define novel clinical phenotypes based on biopsy results to enhance biomarker discovery.*Methods: Retrospective analysis of kidney biopsy…
2022 American Transplant Congress
Genotype and Phenotype Analysis and the Transplantation Strategy in Children with Uremia Caused by Nephronophthisis
J. Li, H. Zhang, X. Su, J. Li, S. Wu, W. Wu, L. Ling, Q. Fu, C. Wu, L. Liu, C. Wang
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: Nephronophthisis- related ciliopathies(NPHP- RC), as an important cause of children's end-stage renal disease(ESRD), has strong genotype and phenotype heterogeneity, and the transplantation strategy of…
2022 American Transplant Congress
The Impact of Food Insecurity on Pediatric Kidney Transplant Outcomes
A. Moin, J. Krissberg, D. Matossian, P. Verghese
Pediatric Nephrology, Lurie Children's Hospital, Chicago, IL
*Purpose: We previously demonstrated a prevalence of food insecurity (FI) of 26.7% at our institution, in a pilot study of 45 pediatric kidney transplant (pedsKTx)…