Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Association between Sarcopenia and Nutritional Factors in Kidney Transplant Recipients
A. Kosoku¹, J. Uchida¹, T. Ishihara², T. Iwai¹, H. Shimada¹, K. Kabei¹, S. Nishide¹, T. Naganuma¹, T. Nakatani¹
¹Urology, Osaka City University Graduate School of Medicine, Osaka, Japan, ²Innovative and Clinical Research Promotion Center, Gifu University Hospital, Gihu, Japan
*Purpose: Malnutrition is an important risk factor for the development of sarcopenia. Several methods are used for the assessment of nutritional status including serum albumin…
2020 American Transplant Congress
Recipient Myeloid Cell Myeloperoxidase is Required for Nk Cell Activation During Antibody-Mediated Allograft Rejection
S. Miyairi, N. Dvorina, K. S. Keslar, A. Valujskikh, W. M. Baldwin, R. L. Fairchild
Immunology, Cleveland Clinic Lerner Research Institute, Cleveland, OH
*Purpose: Dysregulated donor-specific antibody (DSA) responses are induced in B6.CCR5-/- mice transplanted with complete MHC mismatched A/J kidney allografts and are required for rejection of…
2020 American Transplant Congress
Medical and Psychosocial Reasons for Deferral and Denial Following Kidney Transplant Evaluation at a VA Transplant Center
D. Katz¹, E. Siniff², M. L. Sanders³, P. Manay¹, P. Ten Eyck⁴
¹Surgery, University of Iowa, Iowa City, IA, ²Transplant, Iowa City Veterans Affairs Hospital, Iowa City, IA, ³Internal Medicine, University of Iowa, Iowa City, IA, ⁴ICTS, University of Iowa, Iowa City, IA
*Purpose: VA kidney transplant patients present challenges that may limit their listing opportunities in the private sector. We sought to study the medical and psychosocial…
2020 American Transplant Congress
Incident Malignancies among Post Kidney-Transplant Patients by Type of Induction Immunosuppression and by Age
L. Wang, J. Motter, S. Bae, D. Segev, M. McAdams DeMarco
Johns Hopkins University, Baltimore, MD
*Purpose: Adult kidney-transplant (KT) recipients have a differential risk of malignancies based on their induction immunosuppression (IS) therapy. However, older recipients are more likely to…
2020 American Transplant Congress
Optimal Timing of Renal Transplantation in Simultaneous Heart-Kidney Transplant: A Retrospective Analysis of the UNOS/OPTN Database
A. S. Karim, G. E. Leverson, J. W. Smith, D. P. Foley
Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI
*Purpose: In patients receiving a simultaneous heart-kidney transplant (SHKT) the optimal timing of performing the kidney transplant remains controversial. In the immediate approach (iHKT), the…
2020 American Transplant Congress
Easier Said Than Done? Stated versus Actual Usage of Less-Than-Ideal Kidneys
D. Stewart, H. McGehee, J. Rosendale, D. Klassen
United Network for Organ Sharing, Richmond, VA
*Purpose: Despite long candidate waiting times and a persistent supply to demand gap, less-than-ideal (LTI) kidneys continue to be underutilized in the U.S. Usage rates…
2020 American Transplant Congress
The Economic Impact of National Standardization of Virtual Crossmatch Usage in Kidney Transplantation
J. E. Stanton¹, L. M. Rebellato², H. Pournik¹, J. E. Tuttle-Newhall¹, H. Jones¹, W. Irish¹, D. B. Leeser¹
¹Department of Surgery, East Carolina University, The Brody School of Medicine, Greenville, NC, ²Department of Pathology, East Carolina University, The Brody School of Medicine, Greenville, NC
*Purpose: The implementation of virtual crossmatching (VXM) into conventional protocols may reduce expenditures associated with organ allocation.*Methods: A single center retrospective analysis of the total…
2020 American Transplant Congress
Gene Expression Dynamics Demonstrate Perturbations in Innate and Adaptive Immunity in Kidney Transplantation Patients with Cytomegalovirus Viremia
R. Ahn, J. Schaenman, Z. Qian, V. Groysberg, M. Rossetti, A. Hoffmann, D. Gjertson, M. Deng, E. F. Reed
University of California Los Angeles, Los Angeles, CA
*Purpose: Cytomegalovirus (CMV) viremia and disease continues to cause significant morbidity and mortality in kidney transplant patients with clinical complications including organ rejection and death.…
2020 American Transplant Congress
Donor Derived Cell Free DNA (dd-cfDNA) and Gene Expression Signatures of Antibody-Mediated Rejection (ABMR) May Improve Accuracy of ABMR Diagnosis (Dx)
H. Zhang¹, C. C. Nast², E. Huang³, N. Ammerman³, A. A. Vo³, S. C. Jordan³, M. Toyoda¹
¹Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA, ²Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, ³Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Dd-cfDNA has a clinically meaningful association with early Dx of ABMR. Here, we evaluated dd-cfDNA measured prior to for-cause biopsies (Bx), and also measured…
2020 American Transplant Congress
Patient Reported Medication Nonadherence and Tolerability: Results of a Prospective Observational Study
D. Taber, N. Patel, K. Foster, F. Bartlett, C. Perez, H. Meadows, N. Pilch, A. Posadas, K. Soliman, V. Rao, M. Casey, V. Rohan, J. McGillicuddy, S. Nadig, D. Dubay
MUSC, Charleston, SC
*Purpose: Medication nonadherence (MNA) is a major contributor to late allograft loss in transplantation (txp). Immunosuppression therapy is highly effective at preventing rejection yet presents…