Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Patient-Informed Design of an Educational Website on Living Kidney Donation
M. Keller¹, R. Seibert¹, T. Feeley², L. Kayler¹
¹Erie County Medical Center, Buffalo, NY, ²University at Buffalo, SUNY, Buffalo, NY
*Purpose: Web-based education may be a powerful tool to support kidney patients’ learning about living kidney donation (LKD); however, websites that are not user-friendly can…
2020 American Transplant Congress
Utility of dd-cfDNA in TCMR 1A and Borderline Allograft Rejection
E. Stites¹, D. Kumar², O. Olaitan³, G. Gupta²
¹University of Colorado, Aurora, CA, ²Virginia Commonwealth University, Richmond, VA, ³Rush University, Chicago, CA
*Purpose: The value of donor-derived cell-free DNA (dd-cfDNA, AlloSure) as a molecular marker for the early diagnosis of mild T-cell mediated rejection (Banff TCMR 1A…
2020 American Transplant Congress
Recipient LAG3 Deficiency Results in Antibody-Mediated Rejection of Mouse Renal Allografts
M. Nicosia, R. Fan, J. Lee, V. Gorbacheva, A. Beavers, N. Dvorina, W. M. Baldwin III, R. L. Fairchild, B. Min, A. Valujskikh
Inflammation and Immunity, Cleveland Clinic, Cleveland, OH
*Purpose: Lymphocyte activation gene-3 (LAG3) is a coinhibitory receptor on the surface of T and B lymphocytes, NK cells and plasmacytoid dendritic cells. Its functions…
2020 American Transplant Congress
2-Year Results of a Naturalistic Study of De Novo Extended-Release Tacrolimus Tablets vs. Tacrolimus Immediate-Release Capsules in Kidney Transplant Recipients
J. Hagopian¹, S. January¹, N. Nesselhauf¹, K. Progar¹, T. Horwedel², R. Delos Santos³
¹Barnes-Jewish Hospital, Saint Louis, MO, ²Veloxis Pharmaceuticals, Cary, NC, ³Washington University, Saint Louis, MO
*Purpose: In December 2015, our center instituted a protocol change moving to de novo use of tacrolimus-XR (LCPT). The objective of this extension study is…
2020 American Transplant Congress
Broader Distribution of Kidneys Not Projected to Systematically Favor “Low” Performing OPOs
A. Wilk¹, S. Gustafson², D. Stewart¹, N. Salkowski², D. Zaun², J. Snyder²
¹UNOS, Richmond, VA, ²Hennepin Healthcare Research Institute, Minneapolis, MN
*Purpose: In August 2019, the OPTN Kidney (KI) Transplantation Committee put forth a proposal for public comment to replace DSA and region from KI allocation…
2020 American Transplant Congress
The Effect of Pulsatile Pump Perfusion on Hepatitis C Viremia and Transmission in Kidney Transplantation: A Prospective Pilot Study
R. Forbes¹, B. Concepcion¹, D. Clapper², B. Dubray¹, A. Miller², D. Shaffer¹, K. Johnson²
¹Vanderbilt University Medical Center, Nashville, TN, ²Tennessee Donor Services, Nashville, TN
*Purpose: With increasing utilization of hepatitis C (HCV) viremic donor organs for aviremic recipients, there may be a role for kidney pulsatile pump perfusion to…
2020 American Transplant Congress
Use of Sitagliptin versus Placebo to Reduce the Incidence and Severity of Post-Transplant Diabetes after Kidney Transplantation
H. Wijeweera, J. Hagopian, M. Ramakrishnan, L. Chen, R. Delos Santos
Washington University in St. Louis, Saint Louis, MO
*Purpose: Post-transplant diabetes mellitus (PTDM) is a complication in non-diabetic kidney transplant (KT) recipients due weight gain and use of CNI and corticosteroids in immunosuppression…
2020 American Transplant Congress
Hepatitis C Antibody Seroconversion in Kidney Transplant Patients from HCV Antibody Positive/NAT Negative Donors Does Not Deteriorate Renal Allograft Outcome
R. Rattanavich, M. De Vera, T. Hoang, R. Villicana
Loma Linda University, Transplant Institute, San Bernadino, CA
*Purpose: Prior studies have shown that almost 50% of kidney transplant patients from hepatitis C Ab+/NAT - donors have seroconverted but its impact on renal…
2020 American Transplant Congress
Trust and Transparency in Artificial Intelligence-Aided Immunosuppression Decisions
J. Clement
Information and Decision Sciences, University of Minnesota, Minneapolis, MN
*Purpose: In transplant, there is significant interest in using Artificial Intelligence (including machine learning or predictive models) Clinical Decision Support Systems(AI CDSS). Properly designing and…
2020 American Transplant Congress
Predictors of Estimated GFR and Recurrent Chronic Kidney Disease (CKD) after Simultaneous Liver and Kidney Transplantation (SLKT): Results from the US Multicenter SKLT Consortium
P. Sharma¹, Z. Sui¹, M. Zhang¹, J. Magee¹, P. Barman², Y. Patel³, K. Walters⁴, S. Biggins⁵, A. Schluger⁶, G. Cullaro⁷, R. Wong⁸, J. Lai⁸, J. Jo⁹, J. Sinha⁹, L. VanWagner⁹, E. Verna⁷
¹Michigan Medicine, Ann Arbor, MI, ²UCSD, San Diego, CA, ³Duke, Durham, NC, ⁴UCLA, LA, CA, ⁵University of Washington, Seattle, WA, ⁶Westchester Medical Center, Weschester, NY, ⁷Columbia, New York, NY, ⁸UCSF, San Francisco, CA, ⁹Northwestern, Chicago, IL
*Purpose: SLKT is a life-saving intervention for patients with decompensated cirrhosis and concomitant end stage renal disease, irreversible acute kidney injury and select inherited metabolic…