Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Barriers for Kidney Transplant Evaluation among People Living with HIV and End-Stage Renal Disease in Mississippi
L. A. Shimose¹, M. X. Bueno Rios¹, J. Clark¹, A. Torres², D. Garcia-Anton², W. Cheungpasitporn², P. Vaitla², F. Cabeza-Rivera²
¹Infectious Diseases, University of Mississippi Medical Center, Jackson, MS, ²Nephrology, University of Mississippi Medical Center, Jackson, MS
*Purpose: The number of Kidney transplants (KTx) among people living with HIV (PLWH) who develop end-stage renal disease (ESRD) has been increasing in many transplant…
2020 American Transplant Congress
The Use of dd-cfDNA as a Predictive Tool for Future Proteinuria
S. Jordan¹, P. Sood², J. Bromberg³, D. Brennan⁴
¹Cedars-Sinai, Los Angeles, CA, ²University of Pittsburgh Medical Center, Pittsburgh, PA, ³University of Maryland, Baltimore, MD, ⁴The Johns Hopkins Hospital, Baltimore, MD
*Purpose: Most allografts with proteinuria >1500 mg/dL have new glomerular pathology. In contrast, lower levels of proteinuria are generally associated with non-glomerular, nonspecific histologic changes.…
2020 American Transplant Congress
Enough Initial Tacrolimus Blood Concentration is Crucial Even with Additional Everolimus in Corticosteroid Early Withdrawal Regimen for Kidney Transplant Recipients
H. Sasaki¹, T. Tanabe¹, H. Higuchi¹, T. Tsujimoto², H. Harada¹
¹Kidney Transplant Surgery, Sapporo City General Hospital, Sapporo, Japan, ²Pharmacy, Sapporo City General Hospital, Sapporo, Japan
*Purpose: Everolimus (EVR) in combination with low-dose calcineurin inhibitor has been demonstrated in clinical trials to have comparable efficacy in low immunological risk kidney transplant…
2020 American Transplant Congress
Prevalence of Primary Aldosteronism in Kidney Transplant Recipients: A Cross-Sectional Study
N. Garg, C. D. Votruba, F. Aziz, S. Parajuli, M. Mohamed, A. Djamali, D. A. Mandelbrot
University of Wisconsin-Madison, Madison, WI
*Purpose: The prevalence of primary aldosteronism (PA) in the general hypertensive (HTN) population is more than 5%, and substantially higher at 20% in certain high-risk…
2020 American Transplant Congress
Use of Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers Therapy Prior to Kidney Transplantation Does Not Impact Recovery of Function
G. R. Bohan¹, J. Trofe-Clark¹, T. Fallah¹, M. Norris¹, R. D. Bloom², D. Sawinski², G. Malat¹
¹Pharmacy, Hosp of Univ of Pennsylvania, Philadelphia, PA, ²Renal Div, Univ of Pennsylvania, Philadelphia, PA
*Purpose: The impact of chronically administered medications for renin-angiotensin-aldosterone blockade (e.g. ACE-I, ARB), taken prior to kidney transplant (KTx), on immediate allograft function is unknown.*Methods:…
2020 American Transplant Congress
Does Antibiotic Prophylaxis at Ureteral Stent Removal Reduce Urinary Tract Infections in Kidney Transplant Recipients?
M. Tarokh¹, B. Frainey², M. Fascelli³, D. Goldfarb¹, A. Wee³, M. Eltemamy³
¹Kidney Transplant Surgery, Cleveland Clinic, Cleveland, OH, ²Glickman Urological and Kidney Institute, Urology, Cleveland Clinic, Cleveland, OH, ³Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH
*Purpose: Ureteral stents are commonly placed during kidney transplantation (KT). Urinary tract infections (UTI) are a common risk factor after KT and can have detrimental…
2020 American Transplant Congress
Belatacept Based Early Steroid Withdrawal Regimens: Differential Responses in African Americans and Non-African Americans
N. Wilson¹, A. R. Shields², A. L. Christianson¹, S. Tremblay¹, D. Kaufman³, A. Wiseman⁴, J. P. Leone⁵, P. West-Thielke⁶, A. J. Matas⁷, R. R. Alloway¹, E. S. Woodle¹
¹U Cincinnati, Cincinnati, OH, ²The Christ Hospital, Cincinnati, OH, ³U Wisconsin, Madison, WI, ⁴U Colorado, Denver, CO, ⁵Tampa General, Tampa, FL, ⁶U Illinois Chicago, Chicago, IL, ⁷U Minnesota, Minneapolis, MN
*Purpose: Racial disparities in outcomes of kidney transplant recipients (KTxR) are well-described for early steroid withdrawal (ESW) under calcineurin inhibitor (CNI)-based regimens, however little data…
2020 American Transplant Congress
Src Induces Endothelial-to-Mesenchymal Transition and Renal Allograft Fibrosis via Promoting WNT/β-catenin Pathway
W. Zijie, Z. Gui, M. Zheng, Z. Han, J. Tao, H. Chen, L. Sun, X. Ju, R. Tan, M. Gu
Jiangsu Province Hospital, Nanjing, China
*Purpose: Endothelial-to-mesenchymal(EndMT)is recognized as an important source of myofibroblasts contributing to the pathogenesis of allograft interstitial fibrosis in our previous studies. Increased proto-oncogene tyrosine-protein kinase…
2020 American Transplant Congress
Effects of Kidney Transplantation on Cystogenesis in Kidneys Procured from a Deceased Donor with Autosomal Dominant Polycystic Kidney Disease
M. C. Chumley¹, H. Kim², D. M. Williams³, V. Kumar³, M. Mrug³
¹University of Alabama at Birmingham, Birmingham, AL, ²Radiology, University of Alabama at Birmingham, Birmingham, AL, ³Nephrology, University of Alabama at Birmingham, Birmingham, AL
*Purpose: Autosomal Dominant Polycystic Kidney Disease (ADPKD) patients are not routinely considered as kidney donors for renal transplantation. This is partially due to a concern…
2020 American Transplant Congress
Low Mycophenolic Acid Levels are Associated with More Inflammation on 1 Year Protocol Biopsies and Lower Graft Survival in Kidney Transplant Recipients
J. Huskey, G. Mour, M. Ryan, S. Nair, M. Smith, R. Heilman
Mayo Clinic Arizona, Phoenix, AZ
*Purpose: Data is limited on the association of Mycophenolic Acid (MPA) concentration on protocol kidney transplant biopsies. Our aim is to compare clinical outcomes and…