Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Comparative Analysis of kSORT Assay for Predicting Acute Renal Allograft Rejection Under Belatacept-Based Immunosuppression
H. Hames¹, M. Sarwal², I. Damm², E. Yanqui¹, A. Burg¹, A. Christianson¹, A. R. Shields¹, D. Hildeman¹, R. R. Alloway¹, E. S. Woodle¹
¹University of Cincinnati, Cincinnati, OH, ²University of California San Francisco, San Francisco, CA
*Purpose: The kSORT (Kidney Solid Organ Response Test) assay uses transcriptomic profiling of peripheral blood to predict the presence of acute rejection (AR) in renal…
2022 American Transplant Congress
Association Between De Novo Donor Specific Antibody and Tacrolimus Trough Levels in Long Term Follow Up Renal Transplantation
N. Fujiyama¹, M. Saito², R. Yamamoto², R. Sagehashi², T. Saito², Y. Aoyama², K. Numakura², T. Habuchi², S. Satoh¹
¹Center for Kidney Disease and Transplantation, Akita University Hospital, Akita, Japan, ²Department of Urology, Akita University Graduate School of Medicine, Akita, Japan
*Purpose: In this study, we aimed to identify the risk factors contributing to the development of donor-specific anti-HLA antibody (DSA) during long-term follow-up of patients…
2022 American Transplant Congress
Variability of Serum Klotho and FGF-23 Levels During the First Two Years After Kidney Transplantation
T. Vazquez-Sanchez¹, M. Sanchez-Niño², P. Ruiz-Esteban¹, V. López¹, J. Delgado¹, A. Ortiz³, D. Hernández¹
¹Nephrology Department, Regional University Hospital (IBIMA), REDinREN (RD16/0009/0006), Malaga (España), Malaga, Spain, ²Nephrology Department, Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz, Universidad Autónoma de Madrid. REDINREN, Madrid, Spain, ³Nephrology Department, Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz, Universidad Autónoma de Madrid. REDINREN, Madrid, Spain, Madrid, Spain
*Purpose: Klotho is a protein produced in renal tubular cells with nephroprotective actions which acts as a co-receptor for phosphaturic factor FGF-23. The natural history…
2022 American Transplant Congress
A Randomised Trial Of Normothermic Machine Perfusion Versus Static Cold Storage In Donation After Circulatory Death Renal Transplantation
S. Hosgood¹, C. Callaghan², C. Wilson³, G. Oniscu⁴, B. Phillips⁵, L. Bates³, L. Smith⁶, M. L. Nicholson⁷
¹Surgery, University of Cambridge, Cambridge, United Kingdom, ²Transplant, Guys & St Thomas's, London, United Kingdom, ³Transplant, Freeman Hospital, Newcastle, United Kingdom, ⁴Edinburgh Royal Infirmary, Edinburgh, United Kingdom, ⁵Transplant, Guy's & St Thomas's, London, United Kingdom, ⁶NHSBT, NHSBT, Bristol, United Kingdom, ⁷University of Cambridge, Cambridge, United Kingdom
*Purpose: Kidneys from donation after circulatory death (DCD) donors are more susceptible to cold storage injury and have a high risk of delayed graft function…
2022 American Transplant Congress
Sodium-Glucose Cotransporter 2 Inhibitors to Treat Diabetes Mellitus After Kidney Transplant
H. M. Brokmeier¹, S. B. Leung¹, A. Kukla², K. C. Mara³, P. Shah⁴, Y. Kudva⁴, G. K. Mour⁵, H. M. Wadei⁶, J. M. Hill⁷, M. D. Stegall⁸, A. Lemke¹
¹Pharmacy, Mayo Clinic, Rochester, MN, ²Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ³Health Sciences Research, Mayo Clinic, Rochester, MN, ⁴Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN, ⁵Nephrology Transplant, Mayo Clinic, Phoenix, AZ, ⁶Nephrology, Mayo Clinic, Jacksonville, FL, ⁷Transplant, Mayo Clinic, Rochester, MN, ⁸Division of Transplant Surgery, Mayo Clinic, Rochester, MN
*Purpose: This study describes experience prescribing sodium-glucose cotransport 2 inhibitors (SGLT2i) after kidney transplant to evaluate safety and effectiveness.*Methods: This is a retrospective, institutional review…
2022 American Transplant Congress
Eliminating Hepatitis C Positive Status from Kidney Donor Profile Index (KDPI) Calculations Results in Improved Transplant Rates and Outcomes in an Elderly Veteran Population
R. Lopez-Soler¹, A. Thorndyke¹, C. Trotter¹, A. Abadier², M. Samra¹
¹Surgery, Transplantation, Edward Hines Jr. Veterans Administration Hospital, Hines, IL, ²Surgery, Loyola University Medical School, Maywood, IL
*Purpose: Overall mortality on the kidney transplant waiting list is higher for older patients. The average age of waitlisted veteran patients is 64, with patients…
2022 American Transplant Congress
Early Experience with OmniGraf® Biomarker Surveillance in Kidney Transplant Patients in the First-Year Post-Transplant and Beyond
V. Paramasivam¹, W. Ally², B. Sivakumar³, B. Greco¹, M. Germain¹
¹Baystate Medical Center, Springfield, MA, ²Eurofins Transplant Genomics, Framingham, MA, ³Dartmouth College, Hanover, NH
*Purpose: Non-invasive rejection biomarkers continue to evolve with recent data supporting the use of combined gene expression and donor derived cell-free DNA (dd-cfDNA) in kidney…
2022 American Transplant Congress
Living Related Kidney Donation for Alternative Complement Pathway Diseases: Long-Term Outcomes
Y. Caliskan¹, S. Safak², A. B. Dirim², A. Velioglu³, B. Yelken⁴, O. A. Oto², A. Yildiz⁵, N. Garayeva², H. Yazici², A. Ersoy⁵, A. Turkmen⁴, K. L. Lentine¹
¹Saint Louis University, Saint Louis, MO, ²Istanbul University, Istanbul, Turkey, ³Marmara University, Istanbul, Turkey, ⁴Koc University Hospital, Istanbul, Turkey, ⁵Uludag University, Bursa, Turkey
*Purpose: Atypical hemolytic-uremic syndrome (aHUS) and C3 glomerulopathy (C3G) are rare conditions that cause severe kidney disease. Data to guide the evaluation of living related…
2022 American Transplant Congress
Presence of AT1R Antibody Pre-Transplant Does Not Correlate with Rejection in a Large Pediatric Kidney Transplant Cohort
K. Hitchman¹, P. K. Shah¹, D. Fritze¹, R. Hinojosa², D. Ranch¹
¹University Health Transplant Institute, San Antonio, TX, ²Pharmacy, University Health Transplant Institute, San Antonio, TX
*Purpose: Describe correlations between pre-transplant (PreTXP) presence of anti-angiotensin II receptor type 1 antibodies (AT1RAb) and post-transplant (PostTXP) outcomes in a pediatric kidney transplant (PKT)…
2022 American Transplant Congress
Sensitization and BK Viremia; Risk Following Sub-Clinical COVID-19 Infection in Pediatric Kidney Transplant Recipients
E. Benz¹, M. Chandran², J. Chuita¹, K. McKinnon¹, A. Sikora¹, M. Bock¹, E. Blanchette¹
¹Children's Hospital Colorado, Aurora, CO, ²University of North Carolina, Chapel Hill, NC
*Purpose: In contrast to high morbidity and mortality of COVID-19 infection (COVIDi) in adult kidney transplant (KT) recipients, these sequelae appear to be muted in…