Articles tagged "Kidney transplantation"

2020 American Transplant Congress
How Prepared are Potential Donors to Donate?: Racial/Ethnic Differences in Potential Kidney Donors’ Knowledge and Education Before Starting Evaluation
A. Waterman¹, O. N. Ranasinghe¹, Y. Cui², J. L. Beaumont², D. Adey³, U. Reddy⁴, B. Campbell⁵, F. L. Weng⁶
¹Division of Nephrology, David Geffen School of Medicine, Los Angeles, CA, ²Terasaki Research Institute, Los Angeles, CA, ³Division of Nephrology, UCSF Health, San Francisco, CA, ⁴UC Irvine, Irvine, CA, ⁵Cedars Sinai Medical Center, Los Angeles, CA, ⁶St. Barnabas Medical Center, Livingston, NJ
*Purpose: Potential living donors of different races/ethnicities present for kidney donor evaluation with varying levels of knowledge.*Methods: We surveyed potential living donors about how they…
2020 American Transplant Congress
Socioeconomic and Financial Challenges Affecting 2500 Potential Living Kidney Donors’ Pursuit of Donation
A. Waterman¹, O. N. Ranasinghe¹, Y. Cui², J. L. Beaumont², D. Adey³, U. Reddy⁴, B. Campbell⁵, F. L. Weng⁶
¹Division of Nephrology, David Geffen School of Medicine, Los Angeles, CA, ²Terasaki Research Institute, Los Angeles, CA, ³UCSF Health, San Francisco, CA, ⁴UC Irvine, Irvine, CA, ⁵Cedars Sinai Medical Center, Los Angeles, CA, ⁶St. Barnabas Medical Center, Livingston, CA
*Purpose: To identify financial factors that affect living kidney donors’ attitudes and progress towards donation, we conducted a survey of 2576 potential living donors [48%…
2020 American Transplant Congress
Contralateral Upper Tracturothelial Carcinoma after Primary Radical Nephroureterectomy in Kidney Transplant Patients
Z. Wang, J. Lin, Y. Zhu, Y. Guo, Y. Tian
Capital Medical University, Beijing, China
*Purpose: The purpose of the present study was to evaluate the incidence and risk factors of contralateral upper tract urothelial carcinoma (UTUC) after primary radical…
2020 American Transplant Congress
Improving Access to Transplantation and Outcomes for African American Patients
D. Bekbolsynov, O. Ekwenna, B. Mierzejewska, J. Borucka, S. A. Khuder, M. Rees, R. Green, S. Stepkowski
University of Toledo, Toledo, OH
*Purpose: Black or African American patients are clearly disadvantaged in comparison to Caucasian patients both in terms of the access to kidney transplantation and post-transplant…
2020 American Transplant Congress
In Silico Deconvolution of Whole Blood RNA-Seq Data from Iscalimab Phase IIa Study in Renal Transplant Reveals Insights Into Mechanism of Action and Superiority of Iscalimab Compared to Tacrolimus
J. S. Rush
Autoimmunity, Transplantation and Inflammation, Novartis Institutes for Biomedical Research, Basel, Switzerland
*Purpose: A recent Phase 2 clinical study indicated that iscalimab, a pathway blocking, non-depleting anti-CD40 antibody, showed non-inferiority on a composite clinical endpoint, and improved…
2020 American Transplant Congress
Autologous Expanded Tregs Promote Bone Marrow Engraftment and Donor Kidney Survival in Non-Human Primate Chimerism Model
K. Bruestle¹, P. Alonso-Guallart¹, H. Sakai¹, F. Fredriksson¹, B. Piegari¹, E. Lopes¹, G. Pierre¹, A. Shou¹, D. Ekanayake-Alper¹, J. Weiner¹, A. Iuga², S. M. Coley², M. Sykes¹, A. Griesemer¹
¹Columbia Center for Translational Immunology, Columbia University, New York City, NY, ²Department of Pathology and Cell Biology, Columbia University, New York City, NY
*Purpose: Mixed chimerism (MC) induced with non-myeloablative conditioning in monkeys and humans induces tolerance to 70% of kidney grafts transplanted at the time of BMT.…
2020 American Transplant Congress
Thymoglobulin Induction in Kidney Transplant Recipients: A Single Center Experience Comparing 3 Mg/kg vs 5 Mg/kg Cumulative Dosing
K. Progar¹, S. January¹, N. Nesselhauf¹, J. Hagopian¹, A. Malone²
¹Transplant, Barnes-Jewish Hospital, St. Louis, MO, ²Transplant Nephrology, Washington University, St. Louis, MO
*Purpose: Beginning in 2016, our center implemented a protocol change to thymoglobulin (r-ATG) induction dosing in kidney transplant recipients at low rejection risk from 5…
2020 American Transplant Congress
Calcium Level-Dependence of the Adverse Effect of Tertiary Hyperparathyroidism on Graft Survival in Renal Transplant Recipients
M. Okada, T. Tomosugi, T. Hiramitsu, K. Futamura, A. Kanda, N. Goto, S. Narumi, T. Ichimori, Y. Watarai
Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan
*Purpose: Tertiary hyperparathyroidism (THPT) is a condition in which hyperparathyroidism persists after renal transplantation (RTx), and is a frequent complication. The aim of this retrospective…
2020 American Transplant Congress
Treatment of Chronic Active Antibody Mediated Rejection in Kidney Transplant Recipients is Associated with Increased Risk of Urinary Tract Infections and Pneumonia
E. Joachim, S. Parajuli, K. Swanson, F. Aziz, N. Garg, M. Mohamed, D. Mandelbrot, A. Djamali
University of Wisconsin, Madison, WI
*Purpose: Infections are a common cause of morbidity and mortality after kidney transplantation. Chronic active antibody mediated rejection (cABMR) is a leading cause of kidney…
2020 American Transplant Congress
Clinical Implication of Tertially Lymphoid Tissue in the Renal Graft
M. Saito¹, Y. Lee², Y. Sato², S. Narita¹, S. Satoh¹, M. Yanagita², T. Habuchi¹
¹Urology, Akita University Hospital, Akita, Japan, ²Nephrology, Kyoto University Graduate School of Medicine, Kyoto, Japan
*Purpose: Tertialy lymphoid organs (TLTs) are defined as inducible lymphoid tissues that arise in non-lymphoid organs, and chronic sustained inflammation is one of the most…