Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Donor Derived Cell Free DNA (dd-cfDNA) and Gene Expression Signatures of Antibody-Mediated Rejection (ABMR) May Improve Accuracy of ABMR Diagnosis (Dx)
H. Zhang¹, C. C. Nast², E. Huang³, N. Ammerman³, A. A. Vo³, S. C. Jordan³, M. Toyoda¹
¹Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA, ²Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, ³Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Dd-cfDNA has a clinically meaningful association with early Dx of ABMR. Here, we evaluated dd-cfDNA measured prior to for-cause biopsies (Bx), and also measured…
2020 American Transplant Congress
Patient Reported Medication Nonadherence and Tolerability: Results of a Prospective Observational Study
D. Taber, N. Patel, K. Foster, F. Bartlett, C. Perez, H. Meadows, N. Pilch, A. Posadas, K. Soliman, V. Rao, M. Casey, V. Rohan, J. McGillicuddy, S. Nadig, D. Dubay
MUSC, Charleston, SC
*Purpose: Medication nonadherence (MNA) is a major contributor to late allograft loss in transplantation (txp). Immunosuppression therapy is highly effective at preventing rejection yet presents…
2020 American Transplant Congress
Early Steroid Withdrawal in HIV+ Kidney Transplant Recipients is Associated with Increased Acute Rejection by 1 Year
W. A. Werbel¹, S. Bae², S. Yu³, F. Al-Ammary⁴, C. M. Durand¹, D. L. Segev³
¹Infectious Diseases, Johns Hopkins University, Baltimore, MD, ²Epidemiology, Johns Hopkins University, Baltimore, MD, ³Surgery, Johns Hopkins University, Baltimore, MD, ⁴Nephrology, Johns Hopkins University, Baltimore, MD
*Purpose: Kidney transplantation among HIV+ recipients (HIV+ KT) is increasing, with excellent outcomes. Acute rejection (AR), however, is 2-3-fold more common than in HIV- KT.…
2020 American Transplant Congress
Recurrent Diabetic Nephropathy Post Kidney Transplant is Associated with High Risk of Mortality
A. Kukla, M. Merzkani, W. Park, B. Smith, S. Turkevi-Nagy, P. Zhang, X. Benavides, M. Morales Alvarez, A. Denic, A. Bentall, Y. Kudva, M. D'Costa, P. Alexander, M. Stegall
Mayo Clinic, Rochester, MN
*Purpose: The goal of the study was to determine the incidence of recurrent diabetic kidney disease (DKD) after kidney transplantation (KT) and assess its correlation…
2020 American Transplant Congress
Trends in Time to Graft Loss by Dialysis Vintage
P. Ahearn, C. Lenihan, J. Scandling
Stanford University, Palo Alto, CA
*Purpose: Preemptive transplantation has been shown to be beneficial regarding all-cause graft failure compared to transplantation after dialysis initiation, and transplantation after a shorter time…
2020 American Transplant Congress
Tissue Specificity and the Role of Lymphocytes in Estrogen-Mediated Protection from Renal Ischemia Reperfusion Injury
P. T. Hernandez, C. S. O'Brien, S. J. Concors, L. N. Krumeich, Z. Wang, G. Ge, W. Hancock, M. H. Levine
Hospital of the University of Pennsylvania, Philadelphia, PA
*Purpose: Renal ischemia reperfusion injury (IRI) is a major contributor to delayed graft function (DGF) in kidney transplantation. We previously demonstrated lower rates of DGF…
2020 American Transplant Congress
Simultaneous Robotic Kidney Transplantation and Sleeve Gastrectomy versus Transplant Alone for Morbidly Obese Patients with End-Stage Renal Failure: A Prospective Randomized Trial
K. A. Tulla, P. West-Thielke, P. DiCocco, O. Okoye, K. Bruno, J. Almario Alvarez, M. Spaggiari, I. G. Tzvetanov, E. Benedetti
University of Illinois at Chicago, Chicago, IL
*Purpose: The purpose of this study is to demonstrate that simultaneous robotic assisted kidney transplant and robotic assisted sleeve gastrectomy results in fewer surgical complications…
2020 American Transplant Congress
Role of Genetic Studies in Reclassifying Cause of End Stage Kidney Disease among Kidney Transplant Candidates
M. El Ters¹, F. Pinto e Vairo², F. C. Fervenza¹, M. Alexander³, F. G. Cosio¹, H. Amer¹, M. Hogan¹
¹Division of Nephrology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, ²Department of Clinical Genomics, Mayo Clinic, Rochester, MN, ³Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
*Purpose: Recent studies evaluating genetic causes of kidney disease have reclassified a subgroup of focal segmental glomerulosclerosis (FSGS) into collagenopathies. This knowledge has implication in…
2020 American Transplant Congress
Impact of Low Dose Donor Specific Anti-HLA Antibodies between Living Donor versus Deceased Donor Kidney Transplantation
S. Kim¹, S. Lee¹, E. Ko¹, T. Ban², J. Min³, H. Yoon⁴, C. Yang¹, B. Chung¹
¹Internal Medicine, Seoul St. Mary's Hospital, Seoul, Korea, Republic of, ²Internal Medicine, Eunpyeong St. Mary's Hospital, Seoul, Korea, Republic of, ³Internal Medicine, Bucheon St. Mary's Hospital, Seoul, Korea, Republic of, ⁴Internal Medicine, Incheon St. Mary's Hospital, Seoul, Korea, Republic of
*Purpose: Presence of donor specific anti-HLA antibody (HLA-DSA) has significant impact on the short term and long term allograft outcomes after kidney transplantation. However, the…
2020 American Transplant Congress
Impact of Enhanced Recovery after Surgery Protocols on Robotic Living Kidney Donor Outcomes: A Single Center Experience
B. Ruch, A. Sharma, J. Amery, C. Bhati, A. Khan, A. Cotterell, M. Scott, M. Levy
Virginia Commonwealth University, Richmond, VA
*Purpose: Traditional management of living donor nephrectomies includes intraoperative volume loading to maintain renal perfusion and urine output. Recently our center initiated fluid restriction as…