Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Predictors of Estimated GFR and Recurrent Chronic Kidney Disease (CKD) after Simultaneous Liver and Kidney Transplantation (SLKT): Results from the US Multicenter SKLT Consortium
P. Sharma¹, Z. Sui¹, M. Zhang¹, J. Magee¹, P. Barman², Y. Patel³, K. Walters⁴, S. Biggins⁵, A. Schluger⁶, G. Cullaro⁷, R. Wong⁸, J. Lai⁸, J. Jo⁹, J. Sinha⁹, L. VanWagner⁹, E. Verna⁷
¹Michigan Medicine, Ann Arbor, MI, ²UCSD, San Diego, CA, ³Duke, Durham, NC, ⁴UCLA, LA, CA, ⁵University of Washington, Seattle, WA, ⁶Westchester Medical Center, Weschester, NY, ⁷Columbia, New York, NY, ⁸UCSF, San Francisco, CA, ⁹Northwestern, Chicago, IL
*Purpose: SLKT is a life-saving intervention for patients with decompensated cirrhosis and concomitant end stage renal disease, irreversible acute kidney injury and select inherited metabolic…
2020 American Transplant Congress
Crispr-Based Diagnostics for Rejection and Opportunistic Infection Detection in Kidney Transplantation
I. T. Lape¹, M. M. Kaminski², E. Akalin³, J. Collins², L. W. Riella¹
¹Medicine, Renal Division, Brigham and Women's Hospital, Boston, MA, ²Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, ³Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY
*Purpose: There is an unmet need in transplantation to identify allograft injury non-invasively. More than 50% of patients with kidney transplants lose their grafts within…
2020 American Transplant Congress
Acute Kidney Injury in Deceased Organ Donors and Kidney Transplant Outcomes Using a Novel Data Source
E. M. Sonnenberg, J. Hsu, J. Cohen, V. Potluri, M. H. Levine, P. L. Abt, P. P. Reese
Perelman School of Medicine, University of Pennsyl, Philadelphia, PA
*Purpose: The kidney shortage necessitates innovative approaches to expand the donor pool. Acute kidney injury(AKI) is common among deceased donors and a risk factor for…
2020 American Transplant Congress
Early Outcomes with the Liver-Kidney Safety Net
R. M. Cannon¹, D. S. Goldberg², D. E. Eckhoff¹, D. J. Anderson¹, B. J. Orandi¹, J. E. Locke¹
¹University of Alabama at Birmingham, Birmingham, AL, ²University of Miami, Miami, FL
*Purpose: A safety net policy was implemented in August 2017 giving liver alone recipients with significant renal dysfunction post-transplant priority for subsequent renal transplantation. This…
2020 American Transplant Congress
Change In i-IFTA Associated with Treatment of Rejection
N. Garg, B. C. Astor, S. Parajuli, F. Aziz, M. Mohamed, W. Zhong, A. Djamali, D. A. Mandelbrot
UW-Madison, Madison, WI
*Purpose: Recent studies have shown that inflammation in areas of interstitial fibrosis and tubular atrophy (i-IFTA) is associated with worse kidney allograft outcomes. How i-IFTA…
2020 American Transplant Congress
Apoptotic Exosome-Like Vesicles are Associated with Alloimmune Vascular Injury in Kidney Transplant Recipients
M. Dieude¹, E. Boilard², I. Allaeys², A. Deneault-Marchand¹, J. Turgeon¹, E. Dore², S. Lariviere-Beaudoin¹, A. Karakeussian-Rimbaud¹, S. Collette³, L. Senecal³, M. Hebert¹, H. Cardinal¹
¹Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada, ²Centre de Recherche du Centre Hospitalier de l'Université de Québec, Quebec, QC, Canada, ³Hopital Maisonneuve-Rosemont, Montreal, QC, Canada
*Purpose: There is no non-invasive biomarker of alloimmune vascular injury. We have previously characterized exosome-like vesicles enriched in active proteasome and LG3 (ApoExo) that are…
2020 American Transplant Congress
First Case of Simultaneous Living Related Parathyroid- and Kidney Transplantation Into a Child
N. Vallant¹, M. Sinha², P. Gogalniceanu¹, M. Cheung², C. Boffa³, M. Irving², P. Carroll², J. Hubbard¹, R. Gokmen¹, N. Ware², N. Mamode¹, N. Kessaris¹
¹Renal Transplant and Vascular Access, Guy's Hospital London, London, United Kingdom, ²Renal Transplant and Vascular Access, Evelina London Children's Hospital, London, United Kingdom, ³Renal Transplant and Vascular Access, Portsmouth Hospitals NHS Trust, London, United Kingdom
*Purpose: Inherited hypoparathyroidism can lead to life threatening episodes of hypocalcaemia as well as to end stage renal failure at a young age. We are…
2020 American Transplant Congress
Comparison of Outcome Between Low-Dose Rabbit Anti-Thymocyte Globulin and Basiliximab in Low-Risk Living Donor Kidney Transplantation
S. Kim, M. Lim, J. Kwon, E. Jeong, J. Yang, K. Kim, K. Lee, O. Lee, J. Joh
Transplantation, Samsung Medical Center, Seoul, Korea, Republic of
*Purpose: For preventing immunological rejection after kidney transplantation, induction immunosuppressant agents such as basiliximab or rabbit anti-thymocyte globulin (r-ATG) are mostly used nowadays. We compared…
2020 American Transplant Congress
Measuring Environmental Elemental Exposure in the Hair Allows to Identify Kidney Transplant Recipients at Risk of Acute Rejection
A. Angeletti¹, I. Gandolfini², C. Cantarelli², U. Maggiore², L. Gaetano¹, E. Fiaccadori², J. Reid-Adam³, J. Saland³, P. Curtin³, A. Curtin³, C. Austin³, P. Cravedi³
¹St. Orsola Hospital, University of Bologna, Bologna, Italy, ²Parma University, Parma, Italy, ³Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Most biomarkers are representative of a single moment in time, which, even when repeatedly assessed, may not capture trends or variability. Hair is a…
2020 American Transplant Congress
Transplantation of HCV Positive Kidneys Confers Excellent Outcomes for HCV Infected and Uninfected Recipients
J. Torabi, N. Muhdi, A. Montal, J. Melvin, Y. Miura, J. P. Rocca, M. Ajaimy, L. Lirano, Y. Azzi, C. Pynadath, O. Alani, E. Akalin, S. Greenstein, M. Kinkhabwala, J. A. Graham
Montefiore Medical Center, Bronx, NY
*Purpose: Hepatitis C positive (HCV+) donor kidneys were previously transplanted only into HCV infected recipients (D+/R+). Availability of direct acting anti-virals (DAA) has facilitated the…