Articles tagged "Kidney transplantation"

2022 American Transplant Congress
The Natural History of De Novo DSA After Kidney Transplantation
C. López del Moral¹, N. Lachmann², S. Hergovits², D. Stauch², A. Akifova³, M. Naik³, B. Osmanodja³, D. Schmidt³, K. Budde³
¹Nephrology department-IDIVAL, Hospital Universitario Marqués de Valdecilla, Santander, Spain, ²Institute for Transfusion Medicine, HLA-Laboratory, Charité - Universitätsmedizin, Berlin, Germany, ³Department of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin, Berlin, Germany
*Purpose: De novo donor-specific antibodies(dnDSA) are key in the diagnosis of antibody-mediated rejection(ABMR) and are related to graft loss(GL). Luminex® provides semi-quantitative information with the…
2022 American Transplant Congress
Understanding the Heterogeneity of Alloreactive Natural Killer (NK) Cell Function in Kidney Transplant Recipients
D. Ruan, M. Fribourg, N. Chun, P. Cravedi, A. Horowitz, P. Heeger
Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Emerging evidence indicates that human NK cells are a heterogeneous population of lymphocytes that are activated upon ligation of one or more activating receptors…
2022 American Transplant Congress
The Ties That Transplant: The Social Network Determinants of the Living Kidney Donor Relationship Distribution
J. Daw
Sociology & Criminology, The Pennsylvania State University, University Park, PA
*Purpose: To describe and explain the distribution of social relationships of living kidney donors to kidney transplant recipients.*Methods: Using an original dataset of transplant candidates…
2022 American Transplant Congress
Donor Macrophage Depletion Improves Kidney Graft Function Despite Long Cold Ischemia
C. Jordan¹, A. Dangi², X. Luo¹
¹Duke University School of Medicine, Durham, NC, ²Medicine, Duke University, Durham, NC
*Purpose: Prolonged cold ischemia is a known risk factor for delayed graft function and poorer outcomes after kidney transplantation. Overcoming this obstacle is key to…
2022 American Transplant Congress
Survival Comparison of Waitlisted and Renal Transplanted Patients in the European Senior Programme
M. G. Naik¹, V. Greese¹, K. U. Eckardt¹, U. Frei¹, P. Glander¹, L. Liefeldt¹, M. Pigorsch², E. Schaeffner³, K. Budde¹, F. Halleck¹
¹Medical Department, Division of Nephrology and Internal Intensive Care Medicine, Charité, Berlin, Germany, ²Institute of Biometry and Clinical Epidemiology, Charité, Berlin, Germany, ³Institute of Public Health, Charité, Berlin, Germany
*Purpose: Patients >65years are eligible for kidney transplantation (KT) in the European Senior Program (ESP). We compare patient survival of waitlisted (WTL) and transplanted (Tx)…
2022 American Transplant Congress
Survival Benefit of Preemptive Simultaneous Pancreas Kidney Transplantation
E. Montagud-Marrahi¹, E. Cuadrado-Payán¹, E. Hermida¹, D. Cucchiari¹, I. Revuelta¹, J. Del Risco-Zevallos¹, J. Casals¹, N. Esforzado¹, F. Cofan¹, F. Oppenheimer¹, V. Torregrosa¹, J. Ferrer², A. J. Amor³, E. Esmatjes¹, M. Ramirez-Bajo⁴, M. Musquera⁵, B. Bayés¹, J. Campistol¹, F. Diekmann¹, P. Ventura-Aguiar¹
¹Nephrology and Kidney Transplantation Department, Hospital Clínic of Barcelona, Barcelona, Spain, ²Hepatobiliopancreatic and Liver Transplant Department, Hospital Clínic of Barcelona, Barcelona, Spain, ³Diabetes Unit. Endocrinology and Nutrition Department, Hospital Clínic of Barcelona, Barcelona, Spain, ⁴Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació Clínic per a la Recerca, Hospital Clínic of Barcelona, Barcelona, Spain, ⁵Urology Department, Hospital Clínic of Barcelona, Barcelona, Spain
*Purpose: Diabetes mellitus is a well-established risk factor for morbidity and mortality among patients on dialysis, but the evidence regarding the benefits of performing preemptive…
2022 American Transplant Congress
Donor App Increases Awareness and Overall Rates of Living Kidney Donation
T. Shamaa¹, I. Bajjoka¹, H. Kandalaft¹, R. Prashar², M. Callaghan¹, C. Crombez¹, S. J. Serra¹, M. Abouljoud¹, J. Denny¹
¹Transplant and Hepatobiliary Surgery, Henry Ford Transplant Institute, Detroit, MI, ²Transplant Nephrology, Henry Ford Transplant Institute, Detroit, MI
*Purpose: The rate of living donor kidney transplants (LDKTs) performed has declined overall regardless of race. Studies show that web-based tools increase access to living…
2022 American Transplant Congress
Tacrolimus and Mycophenolic Acid Therapeutic Exposure Targets in Black and White Kidney Transplant Recipients
K. Tornatore¹, K. Attwood¹, S. Chang¹, A. Gundroo², B. Murray¹
¹Univeristy at Buffalo/SUNY, Buffalo, NY, ²Ohio State Medical Center, Columbus, OH
*Purpose: Tacrolimus and Mycophenolic Acid(MPA), the preferred immunosuppressive regimen for kidney transplant recipients(KTR), exhibit interpatient pharmacokinetic variability which may impact allograft survival in Black and…
2022 American Transplant Congress
TEMRA CD8 T Cells from Kidney Transplant Recipients Exhibit Enhanced Purinergic P2x4 Receptor-Dependent Proinflammatory and Migratory Responses
G. Tilly¹, T. Doan-Ngoc¹, O. Bonizec¹, C. Masset², R. Danger³, P. Guérif¹, S. Bruneau¹, J. Harb¹, M. Giral¹, C. Pecqueur⁴, S. Brouard¹, N. Degauque¹
¹Nantes Université, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, Nantes, France, ²University Hospital of Nantes, Nantes, France, ³CRTI- INSERM UMR 1064, Nantes, France, ⁴Nantes Université, Univ Angers, INSERM, CNRS, CRCINA, F-44000 Nantes, Nantes, France
*Purpose: Whereas the role of effector memory and TEMRA CD8 in allotransplantation has been clearly evidenced and particularly the direct correlation between intragraft infiltrating CD8…
2022 American Transplant Congress
The Impact of Having Potential Living Donors on Patients’ Access to Kidney Transplantation
E. J. Gordon¹, J. Lee¹, R. Kang¹, J. Caicedo²
¹Northwestern University Feinberg School of Medicine, Chicago, IL, ²Northwestern University, Chicago, IL
*Purpose: Racial/ethnic disparities persist in patients’ access to living donor kidney transplantation (LDKT). Little is known about the relationship between number of potential living donors…