ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "IVIG"

  • 2019 American Transplant Congress

    Effects of IVIG Therapy and FcγR Polymorphisms on BK Virus Nephropathy in Kidney Transplant Recipients

    D. I. Min1, Y. Chang2, T. Shah3

    1Western Univ of Health Sciences, Los Angeles, CA, 2Mendez National Institute of Transplantation Foundation, Los Angeles, CA, 3St. Vincent Medical Center, Los Angeles, CA

    *Purpose: BK Virus Nephropathy (BKVN) is a major complication in kidney transplant patients. Although standard treatment for BKVN is immunosuppression reduction and/or using leflunomide, studies…
  • 2018 American Transplant Congress

    Modified Protocol for ABO-Incompatible Living Donor Liver Transplantation with Rituximab and Intravenous Immunoglobulin without Plasma Exchange

    B-.G. Na, E. Lee, S. Kim, S. Park.

    Center for Liver Cancer, National Cancer Center, Il-san Donggu, Goyang, Republic of Korea.

    Purpose: Since a variety of desensitization strategies including rituximab, intravenous immunoglobulin (IVIG), and plasma exchange (PE) have been introduced, the survival and outcomes of recipients…
  • 2018 American Transplant Congress

    Effect of HLA Antibodies on Graft Survival in Adult Live Donor Liver Transplantation

    M. Simpson,1 M. Akoad,1 F. Gordon,1 Y-.L. Cheah,1 C. Simon,1 J. Pomposelli,2 E. Pomfret.2

    1Transplantation, Lahey Hospital & Medical Center, Burlington, MA; 2Transplantation, University of Colorado Medical Center, Aurora, CO.

    The relevance of HLA antibodies in liver transplantation is currently being re-evaluated. While hyperacute rejections are not an issue, antibody effects on long-term outcomes are…
  • 2018 American Transplant Congress

    Impact of De Novo DSA (DnDSA) on Outcomes in HLA-Sensitized (HS) Patients Transplanted after IVIG + Rituximab Desensitization (DES)

    A. Vo,1 O. Aubert,2 H. Edmund,1 A. Peng,1 R. Najjar,1 S. Supreet,1 J. Choi,1 K. Lim,1 S. Jordan.1

    1Kidney Transplant, Cedars-Sinai Medical Center, LA, CA; 2Paris Translational Research Center for Organ Transplantation, Necker Hospital, Paris, France.

    Introduction: Highly-HLA sensitized patients (HS) with donor specific antibodies (DSA) at transplant are at risk for Type 1 ABMR. However, the incidence of Type 2…
  • 2018 American Transplant Congress

    Pre-Emptive Rituximab and Intravenous Immunoglobulin (IVIg) Fail to Prevent Rejection in Kidney Transplant Recipients (KTx) with Donor Specific Antibodies (DSA)

    J. Crew, R. Vasilescu, E. Campenot, S. Mohan, S. Patel.

    Columbia University, New York, NY.

    Introduction:IVIg and Rituximab have been used successfully to improve transplantation rates in sensitized patients. DSA detected by Flow crossmatch (FXM+) or Luminex® at time of…
  • 2018 American Transplant Congress

    IVIG Induction May Be Helpful in Highly Sensitized Patients after Heart Transplantation

    J. Patel, M. Kittleson, E. Kransdorf, R. Levine, S. Dimbil, D. Geft, D. Chang, L. Czer, J. Kobashigawa.

    Cedars Sinai Medical Center, Los Angeles.

    Purpose: Strategies for sensitized patients undergoing heart transplant include post-op anti-thymocyte globulin (ATG) induction therapy as well as intravenous immunoglobulin (IVIG). We sought to assess…
  • 2018 American Transplant Congress

    Acute Antibody Mediated Rejection Treatment Impact on Class I and Class II Anti-HLA Antibodies in Pediatric Kidney Transplant Recipients

    E. Kincaide,1,2,3 K. Hitchman,1,3 R. Hall,1,2,3 I. Yamaguchi,3 B. Crowther.1,2,3

    1University Health System, San Antonio, TX; 2College of Pharmacy, Pharmacotherapy Division, The University of Texas at Austin, Austin, TX; 3UT Health San Antonio, San Antonio, TX.

    Purpose: Characterize class I and class II donor specific antibodies (DSA) response to acute antibody mediated rejection (AMR) treatment in pediatric kidney transplant recipients (KTR).Methods:…
  • 2018 American Transplant Congress

    Long Term IVIG Infusions for Treatment of Chronic Antibody Mediated Rejection in Pediatric Kidney Transplant Recipients

    A. Al-Uzri,1 C. Shaut,2 S. Iragorri,1 R. Jenkins,1 K. Richardson,1 D. Rozansky,1 M. Wright,1 K. Roayaie.2

    1Pediatrics, Oregon Health & Science University, Portland, OR; 2Transplantation, Oregon Health & Scinece University, Porltand, OR.

    Objectives: The emergence of donor specific antibodies (DSA) after kidney transplantation (Tx) is associated with lower graft survival. The benefit of using intravenous gamma globulin…
  • 2018 American Transplant Congress

    Efficacy and Safety of Acute Antibody Rejection Treatment in Pediatric Kidney Transplant Recipients

    E. Kincaide,1,2,3 K. Hitchman,1,3 R. Hall,1,2,3 I. Yamaguchi,3 B. Crowther.1,2,3

    1University Health System, San Antonio, TX; 2College of Pharmacy, Pharmacotherapy Division, The University of Texas at Austin, San Antonio, TX; 3UT Health San Antonio, San Antonio, TX.

    Purpose: Evaluate the efficacy and safety of acute antibody mediated rejection (AMR) treatment modalities in pediatric kidney transplant recipients (KTR).Methods: A single-center retrospective chart review…
  • 2017 American Transplant Congress

    Experience with the Bacterial Enzyme IdeS (IgG Endopeptidase) for Desensitization of Highly-HLA Sensitized (HS) Kidney Allograft Recipients.

    S. Jordan,1 J. Choi,1 C. Kjellman,2 L. Winstedt,2 X. Zhang,4 S. Louie,1 A. Kang,1 M. Haas,3 A. Vo.1

    1Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; 2Hansa Medical, Lund, Sweden; 3Dept of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA; 4HLA, Cedars-Sinai Medical Center, Los Angeles, CA

    Donor specific antibodies (DSA) create an impenetrable immunologic barrier to transplantation. Current rx aimed at modification of DSAs are not effective in the most HS…
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