2015 American Transplant Congress
Impact of Alloreactivity On Intra-Graft T Cell Homeostasis Following Small Bowel Transplantation
Columbia University Medical Center, New York.
The impact of alloreactivity on the turnover rate, phenotype and repertoire of gut-resident lymphoid cells populating human intestinal allografts is unknown. We prospectively analyzed the…2015 American Transplant Congress
Th17-Mediated Alloimmune Responses Play a Key Role in Intestinal Allograft Rejection in Humans
The Georgetown Transplant Institute, Washington, DC.
The majority of transplanted intestines still falls victim to allograft enteropathy, the underlying mechanisms of which are poorly understood. The purpose of this study was…2015 American Transplant Congress
Severe Sarcopenia and Increased Fat Stores in Pediatric Patients With Liver, Kidney and Intestine Failure
Transplant Division, Dept of Surgery, Indiana University School of Medicine, Indianapolis, IN.
Background: Recent research suggests that measures of frailty, such as nutrition status, may be important predictors of surgical and transplant outcomes. The objectively calculated degree…2015 American Transplant Congress
Thymoglobulin Administration During Multi-Visceral and Isolated Small Bowel Procurement Does Not Adversely Affect the Survival of Harvested Organs
Anti-thymocyte globulin administration in donors before intestinal procurement may result in decreased graft versus-host disease (GVHD) due to reduced recipient lymphocyte trafficking after reperfusion. Reluctance…2015 American Transplant Congress
Hybrid Ostomy New Technique in Intestinal Transplantation
Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL.
Introduction: Many experimental non-invasive methods have been tested to assess the intestinal graft, but none of them proved to be reliable. Biopsy of the intestine…2015 American Transplant Congress
Long-Term Persistence of Innate Lymphoid Cells in the Gut After Intestinal Transplantation
Columbia Center for Translational Immunology, Columbia University Medical Center, New York, NY.
Introduction: Little is known about innate lymphoid cell (ILC) populations in the human gut, and the turnover of these cells and their subsets after transplantation…2015 American Transplant Congress
Pre-Operative Assessment of Body Composition in Adult Multivisceral Transplant Candidates
Department of Surgery, Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA.
Body Mass Index is commonly used, but is likely to be an inexact measurement of nutritional status. For this reason, we examined whether body composition…2015 American Transplant Congress
Allograft Enterectomy as a Life-Saving Procedure and Salvage for Retransplantation
Transplant Surgery, Indiana University School of Medicine, Indianapolis, IN.
Background: Allgraftectomy after solid organ transplantation is usually performed as a palliative therapy. After isolated intestinal transplantation (IIT), allograft enterectomy is sometimes necessary as a…2015 American Transplant Congress
Tacrolimus Trough Concentrations Increase in Intestinal Transplant Recipients During Episodes of Acute Cellular Rejection
Introduction: Acute cellular rejection (ACR) in small bowel transplant recipients is expected to increase intestinal permeability and to reduce intestinal CYP3A/p-glycoprotein activity. These changes may…2015 American Transplant Congress
Immunodeficiency Assessment in Pediatric Intestinal Failure Patients
Intestinal failure (IF) is a clinical condition for which intestinal transplantation may be indicated. Patients without enteral autonomy have an increased risk of malnutrition which…