2015 American Transplant Congress
ILC1 and ILC3 Are the Predominant Intra-Epithelial Lymphoid Populations in Human Small Bowel Grafts
We have shown that differently from native small bowels, NK-like cells (CD45+CD103+CD3-) are the predominant intra-epithelial lymphocytes (IEL) in small bowel grafts (SBG) from 4th…2015 American Transplant Congress
Prevalence and Clinical Outcomes Associated With Vancomycin-Resistant Enterococcal Colonization Or Infection After Small Intestinal Transplantation
BACKGROUND: Vancomycin-resistant enterococcal (VRE) infections cause significant morbidity and mortality amongst SOT recipients. However, little is known about the relevance of VRE in small intestinal…2015 American Transplant Congress
Arteriovenous Fistulas/Grafts for Patients With Intestinal Failure: Innovation or Insanity?
Oxford University Hospitals, Oxford, United Kingdom.
Introduction: Vascular access is the lifeline for chronic intestinal failure patients who are dependent on parenteral nutrition. The traditional use of long term tunnelled central…2015 American Transplant Congress
Chimerism for Early Detection of Graft Versus Host Disease in Intestinal Transplantation
Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL.
Graft versus host disease (GVHD) is a potentially fatal complication after multivisceral transplantation (MVT). By definition, donor cells must be present in the blood of…2015 American Transplant Congress
Everolimus With Low Dose Tacrolimus in Intestinal Transplantation
Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL.
Introduction: Renal dysfunction is a well-known complication after organ transplant given immunosuppression (ISP) with calcineurin inhibitors. This is especially true after intestinal transplant (ITx) given…2015 American Transplant Congress
Incidence, Timing, and Consequence of De Novo Donor Specific Antibody in Intestinal Transplantation
Center for Intestinal Care and Transplant, Medstar Georgetown Transplant Institute, Washington, DC.
The development of denovo Donor specific antibody (dnDSA) in intestinal transplantation (ITx) remains largely unknown. We conducted a prospective and longitudinal analysis of adult and…2015 American Transplant Congress
Creation of a Functional Bio-Artificial Intestinal Segment in Rats
Short bowel syndrome is caused by reduced intestinal length and insufficient absorption. TPN may improve life expectancy, but is potentially associated with severe complications and…2015 American Transplant Congress
Vascularised Composite Allografts and Intestinal Transplantation: Does the Skin Component Provide a Pre-Rejection Marker for the Visceral Organ?
Oxford Transplant Centre, Oxford University Hospitals, Oxford, United Kingdom.
Introduction: Can the skin component of a synchronously transplanted vascularised composite allograft (VCA) be used as a pre-rejection marker for the intestinal transplant (IT)?Methods: Recipients…2015 American Transplant Congress
Impact of Alloreactivity On Intra-Graft T Cell Homeostasis Following Small Bowel Transplantation
Columbia University Medical Center, New York.
The impact of alloreactivity on the turnover rate, phenotype and repertoire of gut-resident lymphoid cells populating human intestinal allografts is unknown. We prospectively analyzed the…2015 American Transplant Congress
Th17-Mediated Alloimmune Responses Play a Key Role in Intestinal Allograft Rejection in Humans
The Georgetown Transplant Institute, Washington, DC.
The majority of transplanted intestines still falls victim to allograft enteropathy, the underlying mechanisms of which are poorly understood. The purpose of this study was…
American Transplant Congress abstracts