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American Transplant Congress abstracts

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Articles tagged "Intestinal transplantation"

  • 2016 American Transplant Congress

    IL-17-Producing CCR6+CD4+ Th17 Cells Drive Intestinal Allograft Rejection in Humans.

    J. Kaiser, C. Cosentino, A. Shukla, C. Desai, R. Girlanda, J. Hawksworth, C. Matsumoto, M. Zasloff, T. Fishbein, A. Kroemer.

    MedStar Georgetown Transplant Institute, Washington DC.

    A. Allograft rejection remains a significant source of mortality and morbidity in intestinal transplant (ITx) recipients. However, the underlying mechanisms remain unclear. The purpose of…
  • 2016 American Transplant Congress

    Kidney Survival Outcomes in Combined Intestinal-Kidney Transplant: An Analysis of the UNOS/OPTN Database 2000-2014.

    A. Sharfuddin, T. Taber, M. Yaqub, I. Moinuddin, A. Khalil, O. Adebiyi, M. Mujtaba.

    Medicine/Nephrology, Indiana University, Indianapolis.

    Background: Intestinal transplants (isolated/modified/multi-visceral) carry a high morbidity and mortality. Kidney outcomes after combined intestinal (IT) with kidney transplant (CIKT) remain largely uninvestigated.Methods: The UNOS…
  • 2016 American Transplant Congress

    Conditional Long Term Intestine Patient and Graft Survival Is Improving Under rATG Immunosuppression in Pediatric Intestine Transplantation.

    N. Celik,1 F. Vyas,1 G. Bond,1 K. Soltys,1 J. Rudolph,2 R. Sindhi,1 G. Mazariegos.1

    1Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; 2Intestinal Care and Rehabilitation Center, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.

    Aim: We reviewed conditional graft survival and short and long term improvements in children receiving rATG (rabbit anti-thymocyte globulin) immunosuppression for intestine transplantation at a…
  • 2015 American Transplant Congress

    Hybrid Ostomy – New Technique in Intestinal Transplantation

    T. Beduschi, J. Garcia, P. Ruiz, A. Tekin, G. Selvaggi, S. Nishida, J. Fan, R. Vianna.

    Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL.

    Introduction: Many experimental non-invasive methods have been tested to assess the intestinal graft, but none of them proved to be reliable. Biopsy of the intestine…
  • 2015 American Transplant Congress

    Long-Term Persistence of Innate Lymphoid Cells in the Gut After Intestinal Transplantation

    J. Weiner, J. Zuber, B. Shonts, S. Yang, M. Martinez, T. Kato, M. Sykes.

    Columbia Center for Translational Immunology, Columbia University Medical Center, New York, NY.

    Introduction: Little is known about innate lymphoid cell (ILC) populations in the human gut, and the turnover of these cells and their subsets after transplantation…
  • 2015 American Transplant Congress

    Pre-Operative Assessment of Body Composition in Adult Multivisceral Transplant Candidates

    R. Cruz, H. Sogawa, G. Bond, K. Soltys, R. Sindhi, G. Mazariegos, A. Humar, A. DiMartini.

    Department of Surgery, Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA.

    Body Mass Index is commonly used, but is likely to be an inexact measurement of nutritional status. For this reason, we examined whether body composition…
  • 2015 American Transplant Congress

    Allograft Enterectomy as a Life-Saving Procedure and Salvage for Retransplantation

    S. Nagai, R. Mangus, B. Ekser, C. Kubal, J. Fridell, A. Tector.

    Transplant Surgery, Indiana University School of Medicine, Indianapolis, IN.

    Background: Allgraftectomy after solid organ transplantation is usually performed as a palliative therapy. After isolated intestinal transplantation (IIT), allograft enterectomy is sometimes necessary as a…
  • 2015 American Transplant Congress

    Tacrolimus Trough Concentrations Increase in Intestinal Transplant Recipients During Episodes of Acute Cellular Rejection

    A. Lichvar,1 D. Deen,2 H. Johnson,1 J. Bonner,3 G. Bond,4 G. Costa,4 R. Cruz,4 K. Abu-Elmagd,5 R. Venkataramanan.6,7

    1Department of Pharmacy and Therapeutics, University of Pittsburgh Medical Center, Pittsburgh, PA; 2Department of Pharmacy, Memorial University Medical Center, Savannah, GA; 3Northern Institute for Cancer Research at Newcastle University, Tyne and Wear, United Kingdom; 4Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA; 5Center for Gut Rehabilitation and Transplantation, Cleveland Clinic, Cleveland, OH; 6Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA; 7Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA.

    Introduction: Acute cellular rejection (ACR) in small bowel transplant recipients is expected to increase intestinal permeability and to reduce intestinal CYP3A/p-glycoprotein activity. These changes may…
  • 2015 American Transplant Congress

    Immunodeficiency Assessment in Pediatric Intestinal Failure Patients

    J. Garcia,1 T. Beduschi,1 C. Biaggi,2 E. Perez,2 A. Tekin,1 M. McGetrick,3 L. Cubley,1 P. Ruiz,1 J. Fan,1 S. Nishida,1 G. Selvaggi,1 R. Vianna.1

    1Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL; 2Pediatrics, University of Miami Miller School of Medicine, Miami, FL; 3University of Miami Miller School of Medicine, Miami, FL.

    Intestinal failure (IF) is a clinical condition for which intestinal transplantation may be indicated. Patients without enteral autonomy have an increased risk of malnutrition which…
  • 2015 American Transplant Congress

    Treatment of Hypertrophic Osteoarthropathy in an Intestinal Transplant Patient After Acute Cellular Rejection

    M. Keck.

    Department of Pharmaceutical and Nutrition Care, Nebraska Medicine, Omaha, NE.

    Background:Hypertrophic osteoarthropathy involves abnormal proliferation of bone at distal extremities. It involves clubbing, periostitis of tubular bones and synovial effusions. Some causes of secondary hypertrophic…
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