ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Interleukin-2 receptor"

  • 2015 American Transplant Congress

    Propensity Score-Weighted Analysis of Induction Therapies in Live Donor Kidney Transplantation in Modern Immunosuppression Era

    B. Tanriover,1 S. Zhang,2 M. MacConmara.3

    1Medicine, UTSW, Dallas, TX; 2Clinical Sciences, UTSW, Dallas, TX; 3Surgery, UTSW, Dallas, TX.

    Background: Induction therapy with interleukin-2 receptor antagonist (IL2-RA) is recommended as a first line agent in living donor renal transplantation (LRT). However, use of IL2-RA…
  • 2015 American Transplant Congress

    Induction With an Interleukin-2 Receptor Antagonist in Sensitized Adult Kidney Transplant Recipients Is Highly Effective and Safe

    J. Casale, J. Fleming, D. Taber, C. Staino, K. Boyle, K. Covert, N. Pilch, H. Meadows, C. Mardis, K. Chavin, C. Bratton, J. McGillicuddy, P. Baliga.

    MUSC, Charleston, SC.

    Background: The effectiveness and safety of induction with basiliximab (IL2RA) in sensitized kidney transplant recipients is not clearly established. The aim of this study was…
  • 2015 American Transplant Congress

    Anti-CD122 + Costimulation Blockade Prolongs Allograft Survival

    D. Mathews,1 L. Higginbotham,1 Y. Dong,1 C. Breeden,1 C. Larsen,1 J. Tso,2 A. Adams.1

    1Emory Transplant Center, Emory University, Atlanta, GA; 2JN Bioscience, Mountanview, CA.

    Introduction: Effective T cell activation and effector function requires (1) cognate antigen recognition (2) appropriate costimulation and (3) successful cytokine signaling. Recently approved strategies to…
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