ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Insulin"

  • 2017 American Transplant Congress

    Total Pancreatectomy with Islet Autotransplantation Improves Quality of Life Allowing for the Resolution of the Intractable Pain with Good Glucose Control in Properly Selected Patients with Chronic Pancreatitis.

    A. Kotukhov,1 J. Solomina,1 E. Konsur,1 K. Cieply,1 L. Basto,1 L.-J. Wang,1 K. Golab,1 M. Tibudan,1 A. Gelrud,2 C. Thomas,2 J. Matthews,1 P. Witkowski.1

    1Surgery, University of Chicago, Chicago, IL; 2Medicine, University of Chicago, Chicago, IL

    Background: There is a group of Total pancreatectomy (TP) is offered as a last option to patients with chronic pancreatitis (CP) who despite optimal treatment…
  • 2017 American Transplant Congress

    10 Years or More of Follow Up After Total Pancreatectomy and Intra Portal Islet Auto Transplantation (TP/IAT) for Treatment of Chronic Pancreatitis, Is It a Durable Operation?

    S. Chinnakotla, T. Dunn, G. Beilman, M. Bellin, T. Pruett, V. Kirchner, J. Wilhelm, M. Freeman, D. Sutherland.

    Surgery, University of Minnesota, Minneapolis

    Background: Total pancreatectomy and intra-portal islet cell auto-transplantation (TP/IAT) is increasingly being utilized for the management of chronic pancreatitis (CP), the benefits being removal of…
  • 2017 American Transplant Congress

    Timing of Mesenchymal Stem Cell Infusions Affects Rejection Free and Overall Islet Allograft Survival.

    N. Kenyon,1 M. Willman,1 D. Han,1 A. Rabassa,1 W. Diaz,1 R. Leeman,1 K. McHenry,2 D. Salomon,3 A. Bartholomew,4 N. Kenyon,1 D. Berman.1

    1Diabetes Research Institute, University of Miami, Miami, FL; 2University of Illinois at Urbana-Champaign, Champaign, IL; 3The Scripps Research Institute, La Jolla, CA; 4University of Illinois at Chicago, Chicago, IL

    We recently demonstrated that autologous, bone marrow-derived mesenchymal stem cells (MSC) promote allogeneic islet engraftment and survival in a streptozotocin induced, cynomolgus monkey model of…
  • 2017 American Transplant Congress

    Diabetes in Liver Transplantation: Evaluation of Management and Associated Clinical Outcomes.

    A. Rogers,2 N. Patel,2 H. Meadows,2 A. Mardis,2 J. Fleming,2 C. Perez,2 I. Lee,2 M. Sell,2 B. O'Brien,2 D. Taber,1 K. Chavin,1 D. Dubay,1 C. Mardis,2 N. Pilch.1

    1Department of Surgry Division of Transplant, Medical University of South Carolina, Charleston, SC; 2Department of Pharmacy, Medical University of South Carolina, Charleston, SC

    PurposeThere is limited data with diabetes management in liver transplant recipients and associated outcomes, this study aims to evaluate the long-term diabetes management in this…
  • 2016 American Transplant Congress

    Evolving to Everolimus: A Safe and Effective Option for Pancreas Transplant.

    S. Yeager, A. Carlson, C. Truax, N. Kenyon, F. Ahmed, J. Corbett, F. Shihab, L. Smith.

    University of Utah Health Care, Salt Lake City, UT.

    Although everolimus is an attractive option for conversion therapy in pancreas tx pts that experience SE's of commonly used immunosuppression, TAC and MPA, there is…
  • 2016 American Transplant Congress

    Total Pancreatectomy with Islet Autotransplantation for Chronic Pancreatitis: Considerations for Early Intervention.

    J. Jolissaint,1 L. Langman,1 C. DeBolt,1 A. Wang,2 D. Strand,2 V. Zaydfudim,1 R. Adams,1 K. Brayman.1

    1Department of Surgery, University of Virginia, Charlottesville, VA; 2Department of Medicine, University of Virginia, Charlottesville, VA.

    Introduction: Total pancreatectomy with islet autotransplantation (TPIAT) provides pain relief for patients with chronic pancreatitis (CP) and the potential to ameliorate the resulting endocrine insufficiency.…
  • 2016 American Transplant Congress

    Deceased Organ Donor Factors Influencing Pancreatic Graft Transplantation and Survival.

    M. Sally, M. Ellis, T. Groat, X. Gao, S. De la Cruz, M. Patel, D. Malinoski.

    Section of Critical Care, Portland VA Health Care System, Portland, OR.

    Criteria for organ acceptance remain inconsistent in pancreatic transplantation. The lack of predictive criteria limits the ability to standardize critical care practices in management of…
  • 2016 American Transplant Congress

    FGF and Wnt Signaling in Pancreatic Progenitor and Beta-Cell Growth.

    S. Afelik,1 N. Yonan,1 B. Pool,2 J. Jensen,2 J. Oberholzer.1

    1Surgery, Division of Transplantation, University of Illinois, Chicago, IL; 2Stem Cell Biology and Regenerative Medicine, Cleveland Clinic Foundation, Cleveland, OH.

    Beta-cell replacement therapy offersa cure for diabetes, but this is limited by the lack of readilyavailable supply of cells. Our goal is generate enough beta-cells…
  • 2016 American Transplant Congress

    Transplantation of Islet Preconditioned with Hydrogen Sulfide Enhances the Graft Function in Diabetic Mice.

    D. Wang, M. Ding, J. Xue, J. Zheng, S. Feng, H. Tian, Y. Li.

    Department of Renal Transplant, Center of Nephropathy, the First Affiliated Hospital, Medical College of Xi'an Jiaotong University, Xi'an, China.

    Background: Islet transplantation is a promising therapy for Type 1 diabetes. However, successful outcomes are hampered by the poor survival of the donor cells after…
  • 2016 American Transplant Congress

    Simultaneous Pancreas and Kidney Transplantation for Type 2 Diabetes.

    K. Wong, W. Bry, H. Mahanty, P. Patel.

    Transplantation, California Pacific Medical Center, San Francisco, CA.

    Introduction: Type 2 diabetes (T2DM) is characterized initially by insulin resistance and later by beta cell failure. Historically, T2DM has been a relative contraindication for…
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