2017 American Transplant Congress
Timing of Mesenchymal Stem Cell Infusions Affects Rejection Free and Overall Islet Allograft Survival.
We recently demonstrated that autologous, bone marrow-derived mesenchymal stem cells (MSC) promote allogeneic islet engraftment and survival in a streptozotocin induced, cynomolgus monkey model of…2017 American Transplant Congress
Diabetes in Liver Transplantation: Evaluation of Management and Associated Clinical Outcomes.
PurposeThere is limited data with diabetes management in liver transplant recipients and associated outcomes, this study aims to evaluate the long-term diabetes management in this…2017 American Transplant Congress
Insulin Therapy in Pancreas Donors as a Predictor of Subsequent Transplant Outcome.
Introduction: Brain stem death causes high levels of systemic catecholamines and inflammation affecting all organs. These changes, and the routine use of high-dose corticosteroids in…2017 American Transplant Congress
Total Pancreatectomy with Islet Autotransplantation Improves Quality of Life Allowing for the Resolution of the Intractable Pain with Good Glucose Control in Properly Selected Patients with Chronic Pancreatitis.
1Surgery, University of Chicago, Chicago, IL; 2Medicine, University of Chicago, Chicago, IL
Background: There is a group of Total pancreatectomy (TP) is offered as a last option to patients with chronic pancreatitis (CP) who despite optimal treatment…2016 American Transplant Congress
Total Pancreatectomy with Islet Autotransplantation for Chronic Pancreatitis: Considerations for Early Intervention.
Introduction: Total pancreatectomy with islet autotransplantation (TPIAT) provides pain relief for patients with chronic pancreatitis (CP) and the potential to ameliorate the resulting endocrine insufficiency.…2016 American Transplant Congress
Deceased Organ Donor Factors Influencing Pancreatic Graft Transplantation and Survival.
Section of Critical Care, Portland VA Health Care System, Portland, OR.
Criteria for organ acceptance remain inconsistent in pancreatic transplantation. The lack of predictive criteria limits the ability to standardize critical care practices in management of…2016 American Transplant Congress
FGF and Wnt Signaling in Pancreatic Progenitor and Beta-Cell Growth.
Beta-cell replacement therapy offersa cure for diabetes, but this is limited by the lack of readilyavailable supply of cells. Our goal is generate enough beta-cells…2016 American Transplant Congress
Transplantation of Islet Preconditioned with Hydrogen Sulfide Enhances the Graft Function in Diabetic Mice.
Background: Islet transplantation is a promising therapy for Type 1 diabetes. However, successful outcomes are hampered by the poor survival of the donor cells after…2016 American Transplant Congress
Simultaneous Pancreas and Kidney Transplantation for Type 2 Diabetes.
Transplantation, California Pacific Medical Center, San Francisco, CA.
Introduction: Type 2 diabetes (T2DM) is characterized initially by insulin resistance and later by beta cell failure. Historically, T2DM has been a relative contraindication for…2016 American Transplant Congress
Evolving to Everolimus: A Safe and Effective Option for Pancreas Transplant.
University of Utah Health Care, Salt Lake City, UT.
Although everolimus is an attractive option for conversion therapy in pancreas tx pts that experience SE's of commonly used immunosuppression, TAC and MPA, there is…
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