2020 American Transplant Congress
TPIAT Outcomes in Diabetic and Non-Diabetic Patients with Chronic Pancreatitis
Virginia Commonwealth University, Richmond, VA
*Purpose: Total pancreatectomy with islet auto-transplantation (TPIAT) is becoming the standard of care for patients with severe chronic pancreatitis (CP). However, it is necessary to…2020 American Transplant Congress
Construction of Three-Dimensional Vascularized Functional Beta-Cells Tissues Using a Layer-by-Layer Cell Coating Technique
*Purpose: Regenerative therapy for type I Diabetes Mellitus has been expected to be a promising treatment. A subcutaneous site is an ideal candidate for stem…2019 American Transplant Congress
Comparison of Functional β-cell Function and Insulin Sensitivity of Functioning Pancreas Transplant According to Pre-Transplant Matsuda’s Index
*Purpose: This study was performed to verify post-transplant improvement of functioning β-cell mass and insulin sensitivity of functioning pancreas transplants according to the degree of…2019 American Transplant Congress
Pre-Operative C-Peptide Predicts Weight Gain after Pancreas Transplantation
Montefiore Medical Center, Bronx, NY
*Purpose: Transplant recipients are susceptible to metabolic syndrome as typified by hyperglycemia, central obesity and increased insulin resistance after transplant, which may precede the onset…2019 American Transplant Congress
Clinical Trial of Allogeneic Islet Transplantation in the Treatment of Diabetes after Renal Transplantation
Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases, Wuhan, China
*Purpose: Diabetes after renal transplantation is one of the most serious complications after renal transplantation. It has a serious impact to the survival of kidney…2019 American Transplant Congress
Donor Insulin Therapy Predicts Better Graft Survival in Pancreas Transplantation
University of Manchester, Manchester, United Kingdom
*Purpose: Organ donors frequently develop hyperglycaemia in intensive care, which is managed with insulin. In islet and solid pancreas transplantation (PT) we reported that Donor…2019 American Transplant Congress
microRNA-375 Provides an Objective Measure of Pancreas Quality in Organ Donors
*Purpose: Donor pancreatic beta cells are at high risk from apoptosis. Objective methods for assessing the quality of donor pancreases for transplantation are limited. We…2019 American Transplant Congress
Assessment of Culture/Preservation Conditions on Survival and Function of Islets
Surgery, Virginia Commonwealth University, Richmond, VA
*Purpose: Culture or preservation of human islets prior to transplantation has been adopted by various centers because it may reduce immunogenicity, suppress exocrine contamination and…2019 American Transplant Congress
Microfluidic Study Analyzing the Effect of Immediate-Release and Extended-Release Tacrolimus on Islet Function
*Purpose: The purpose of this analysis was to quantify the impact of 2 tacrolimus pharmacokinetic profiles on functional changes within human islet cells using a…2019 American Transplant Congress
Insulin Treatment in Pancreas Donors on the Intensive Care is a Marker of Beta Cell Death as Evidenced by microRNA Data
University of Manchester, Manchester, United Kingdom
*Purpose: We showed in prior studies that donor insulin use on intensive care predicts early beta cell dysfunction in islet and solid pancreas transplantation. We…
American Transplant Congress abstracts