2015 American Transplant Congress
A Prospective Pilot Study Evaluating the Safety and Efficacy of Everolimus for the Prevention of CMV and BK Viral Infection (BKV) in Broadly Sensitized Kidney Transplant Recipients Following Desensitization With IVIG and Rituximab: Interim Analysis
Introduction: Everolimus, a second generation mTOR inhibitor, may prevent CMV and BKV infection after kidney transplantation. Broadly sensitized patients are at greater risk of viral…2015 American Transplant Congress
Improving Latent Tuberculosis Diagnosis Before Kidney Transplantation in a Developing Country
Introduction: Tuberculosis has shown to be a great challenge in kidney transplantation, specially in developing countries due to the difficulties in diagnosis and treatment, leading…2015 American Transplant Congress
Preventing Cytomegalovirus Infection in Intermediate-High Risk Liver Transplant Recipients: Acyclovir Vs Valganciclovir
Department of Pharmacy, New York Presbyterian Hospital, New York City, NY.
Cytomegalovirus (CMV) is an opportunistic infection responsible for profound morbidity and mortality among solid organ transplant recipients. A donor and recipient's CMV IgG serostatus influences…2015 American Transplant Congress
Screening Recipients of Increased Risk Donor Organs: A Multicenter Study
Purpose: Policy mandates post-transplant (tx) evaluation of recipients of increased risk donor organs (ROIRDO). PHS guidelines recommend that screening include HIV & hepatitis C virus…2015 American Transplant Congress
Donor and Recipient Pretransplant Polyoma BK Serostatus: Relationship to BK-Viremia After Renal Transplantation
Surgery, Albany Medical College, Albany, NY.
Background:Polyoma virus BK nephropathy is a serious complication after renal transplantation and is associated with a significant risk of graft loss and dysfunction. This study…2015 American Transplant Congress
Mycophenolic Acid Area-Under-Curve (MPA AUC) Levels Sufficient to Prevent Donor-Specific Antibody (DSA) Formation Are Not Associated With Higher Rates of CMV/EBV/BK Viral Infections
PinnacleHealth, Harrisburg, PA.
Background: Prevention of DSA formation and antibody-mediated rejection mandates therapeutic doses of immunosuppressive agents, including MPA. We have shown that MPA AUC monitoring and dose…2015 American Transplant Congress
Role of Universal Decolonization After Kidney Transplant: A Pilot Study
IntroductionInfection is a common cause of morbidity and mortality after kidney transplantation. Despite careful pre-transplantation screening of donors and recipients, vaccination, prophylaxis, and antimicrobial use,…2015 American Transplant Congress
The Impact of Preoperative Antimicrobial Prophylaxis on Device-Related Infections in Recipients of Long-Term Mechanical Circulatory Support (MCS)
1Eastern Virginia Medical School, Norfolk, VA; 2Sentara Norfolk General Hospital, Norfolk, VA.
Purpose: Although preoperative antimicrobial prophylaxis is recommended for patients undergoing long-term MCS device implantation, there is a lack of consensus as to the optimal preoperative…2015 American Transplant Congress
Donor Derived Transmission Events in 2014: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC)
Background: The OPTN DTAC, a multidisciplinary committee, evaluates potential donor derived transmission events (PDDTE), including infections (I) & malignancies (M), to assess for donor transmitted…2015 American Transplant Congress
Is BK Viral Subtype Distribution of Donor And/Or Recipient Important for Subsequent BK Viral Infection After Living-Donor Transplantation?
Background: Source and risk factors for developing BK virus (BKV) infection after renal transplantation are unresolved. By genotyping of urine and blood, we looked for…