2018 American Transplant Congress
Having Your Cake and Eating It Too: An Aggressive Protocol for DSA Treatment Does Not Doom Patients to High Infectious Risk
Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, Washington, DC.
Introduction: Antibody mediated rejection (AMR) is one of the most difficult complications to treat in kidney transplantation. We previously reported on our experience with an…2018 American Transplant Congress
Significant Anti-CMV/BKV Effect of a Modern Everolimus-Based Regimen Comparted to a Standard Tacrolimus-MPA Regimen in De Novo Kidney Transplant Recipients: ATHENA 12 Months Data on Infections
1Athena Study Group, Germany; 2Athena Study Group, France; 3Novartis, Pharma, Germany.
The ATHENA trial was designed to compare everolimus [EVR] in combination with tacrolimus [TAC] or cyclosporine A [CyA] vs. a standard regimen of mycophenolic acid…2018 American Transplant Congress
Frailty is Predictive of Early Post-Transplant Infection in Older Renal Transplant Recipients
Background: Frailty is predictive of postoperative morbidity, including infections in older surgical patients. It is not known if frailty is associated with post-operative infections in…2018 American Transplant Congress
Early Infectious Outcomes of Older Adults Undergoing Kidney Transplantation (KT). A Case Control Study
Study Purpose: Our aim was to investigate if among older KT recipient, the types of infections, number of rejections, graft and patient survival in the…2018 American Transplant Congress
Prediction of BK Viremia by Urine BK Viral Load in Renal Transplant Patients: BK Viral Load Results in Paired Urine and Plasma Samples
BK virus (BKV) associated nephropathy (BKVAN) affects up to 10% of renal transplant recipients, causing graft failure without intervention; a presumptive BKVAN diagnosis is made…2018 American Transplant Congress
Colistin (COL) in Solid Organ Transplant Recipients (SOTR): Friend or Foe?
Cleveland Clinic, Cleveland, OH.
Background: Data on COL use in SOTR are lacking. In other populations, high dose (HD) COL (>4.4mg/kg/day) has been associated with clinical and microbiologic cure…2018 American Transplant Congress
Urinary Tract Infections May Be Associated with De Novo Donor-Specific Anti-Human Leucocyte Antigen Antibodies: Single-Center Study
Introduction: We have recently shown that immunosuppression reduction with BK virus is associated with the development of de novo donor anti-human leukocyte antigen-specific antibodies (dnDSA).…2018 American Transplant Congress
Prospective, Multi-Center Observational Study of Cell-Mediated Immunity for Cytomegalovirus Infection in Kidney Transplant Recipients
Background:T-cell-mediated immunity (CMI) is crucial for the control of CMV infection post-transplant. We evaluated a novel EliSpot assay to determine whether CMI results could predict…2018 American Transplant Congress
Origin and Pattern of Human Polyomaviruses Replication after Kidney Transplantation: A Prospective Study
Background. Human Polyomaviruses (HPyVs) are able to establish latent infection in the kidney of the host. Immunosuppression is recognized risk factor for HPyVs reactivation. Besides…2018 American Transplant Congress
Clinical Outcomes of Kidney Transplant Recipients Infected with Hepatitis C Virus and Treated with Direct-Acting Antiviral Therapy
Introduction:Hepatitis C virus (HCV) infection has negative impact on patient and graft survival in kidney transplant recipients. In the past, treatment of HCV infection post…
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