Articles tagged "Infection"

2018 American Transplant Congress
A National Survey of Valganciclovir Dosing Strategies in Pediatric Solid Organ Transplant Recipients
S. Shaikh, N. Panek, J. Park.
MedStar Georgetown University Hospital, Washington DC; Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago; Michigan Medicine, Ann Arbor.
Objective: The FDA-approved pediatric indication of valganciclovir (VGCV) is limited to cytomegalovirus (CMV) prophylaxis in heart and kidney transplants. The recommended regimen is a daily…
2018 American Transplant Congress
Oral Vancomycin Monotherapy versus Combination Therapy in Solid Organ Transplant Recipients with Uncomplicated Clostridium difficile Infection: A Retrospective Cohort Study
G. Korayem,^1,2,4 K. Eljaaly,^2,3 K. Matthias,^2,4 T. Zangeneh.^4,5
¹Department of Pharmaceutical Practices, Princess Nourah Bint Abdulrahman University, Riyadh, NA, Saudi Arabia; ²Department of Pharmacy Practice and Science, University of Arizona, Tucson, AZ; ³Department of Clinical Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia; ⁴Banner - University Medical Center Tucson, Tucson, AZ; ⁵Division of Infectious Diseases, Department of Medicine, University of Arizona, Tucson, AZ.
Introduction:Solid organ transplant (SOT) recipients are at high risk of Clostridium difficile infection (CDI) and CDI recurrence. A combination of metronidazole and oral vancomycin is…
2018 American Transplant Congress
Increase in Potentially Resistant Non-Aspergillus Molds Isolated in Lung Transplant Recipients after Voriconazole and Posaconazole Prophylaxis
M. Fung,¹ J. Greenland,^2,3 S. Hays,² J. Singer,² J. Golden,² P. Chin-Hong.¹
¹Infectious Diseases, University of California San Francisco, San Francisco, CA; ²Pulmonary and Critical Care, University of California San Francisco, San Francisco, CA.
Background: Lung transplant recipients are at higher risk for invasive fungal infections compared to other solid organs transplant patients. Antifungal prophylaxis with mold-active azoles has…
2018 American Transplant Congress
Humoral Immune Response to Seasonal Influenza Infection in Transplant Recipients
C. Hirzel,¹ V. Ferreira,¹ A. L'Huillier,¹ K. Hoschler,² E. Cordero,³ G. Reid,⁴ J. Englund,⁵ A. Limaye,⁶ A. Humar,¹ D. Kumar.¹
¹UHN, Toronto, Canada; ²Public Health England, London, United Kingdom; ³REIPI, Sevilla, Spain; ⁴LUMC, Chicago; ⁵SCH, Seattle; ⁶UOWMC, Seattle.
Background: Little is known about the serologic response to natural influenza infection in transplant recipients. We describe the hemagglutinin antibody response to influenza A/H1N1 infection…
2018 American Transplant Congress
Cause of ESRD is Not Associated with Risk of Post-Transplant CMV Infection
S. Panzer, S. Peery, B. Astor, A. Djamali, T. Singh.
University of Wisconsin Madison, Madison, WI.
Purpose: Cytomegalovirus (CMV) infection is commonly encountered following kidney transplantation and is associated with patient morbidity and mortality. While preventative pharmacotherapy is used to prevent…
2018 American Transplant Congress
Immunoglobulin Replacement Therapy in Pediatric Renal Transplant Patients
A. Lewis, M. Fasano, D. Zepeda-Orozco.
University of Iowa Hospitals and Clinics, Iowa City, IA.
Immunoglobulin replacement therapy decreases infection frequency in patients with primary immunodeficiency; however, there is limited data regarding the use of intravenous immunoglobulin (IVIG) or subcutaneous…
2018 American Transplant Congress
Transmission of Rabies through Solid Organ Transplant: A Big Issue in China
J. Zhang, J. Lin, Y. Tian, L. Ma, W. Sun, L. Zhang, Y. Zhu, W. Qiu, L. Zhang.
Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Purpose To summarize and analyze the clinical characteristic, prophylaxis and treatment of rabies transmitted through solid organ transplant. Methods Four recipients and their donors diagnosed…
2018 American Transplant Congress
Evaluation of Risk Factors for Progression of Low Level CMV Viremia in Solid Organ Transplant Recipients
Y. Natori, A. Humar, A. Alghamdi, D. Kumar.
Multi Organ Transplant Program, University Health Network, University of Toronto, Toronto, ON, Canada.
Background: Low level CMV viremia is common, and may either progress to higher viral loads that require therapy, or may spontaneously resolve. The clinical predictors…
2018 American Transplant Congress
Serum Beta-(1,3)-D-Glucan as a Case-Finding Tool during an Outbreak of Pneumocystitis jirovecii Pneumonia in Abdominal Transplant Patients
J. Mittal, J. Mogollon, K. Cowman, P. Nori, V. Muggia, G. Minamoto, Y. Puius.
Division of Infectious Diseases, Montefiore Medical Center, Bronx, NY.
Background: Pneumocystis jirovecii pneumonia(PJP) in solid organ transplant (SOT) recipients carries significant morbidity and mortality. There is mounting evidence for ongoing risk of PJP in…
2018 American Transplant Congress
Early versus Late Cytomegalovirus Prophylaxis after Kidney Transplant
M. Harris, J. Byrns, J. Gommer, M. Laub, M. Ellis.
Duke University Hospital, Durham, NC.
Background: Prophylaxis against cytomegalovirus (CMV) is recommended in high-risk patients (CMV D+/R-) and those who are CMVR+ and getting T-cell depletional therapy. It is unclear…