Articles tagged "Infection"

2019 American Transplant Congress
Polyomavirus Genotypes In Renal Transplant Recipients In The United States
N. Khoury¹, C. Thongprayoon², N. Leeaphorn³, J. Bruminhent⁴, W. Cheungpasitporn⁵
¹Henry Ford Transplant Institute, Detroit, MI, ²Mayo Clinic, Rochester, MN, ³University of Missouri, Kansas, MO, ⁴Mahidol University, Bangkok, Thailand, ⁵University of Mississippi, Jackson, MS
*Purpose: BK Polyomavirus (BKV) subtypes and subgroups present uneven geographical distribution, suggesting a potential relationship with ethnicity. In the United States where there is a…
2019 American Transplant Congress
Single-center Retrospective Analysis of Prophylaxis and Treatment of Pneumocystis Carinii Pneumonia in Patients with Poor Renal Function
Y. Fu, J. Pan, Z. Shen
Kidney-Pancreas Transplant Department., Tianjin First Central Hospital, Tianjin, China
*Purpose: Pneumocystis carinii pneumonia (PcP) is a potentially life-threatening complication in renal transplant recipients. Although the use of trimethoprim-sulfamethoxazole (TMP-SMX) chemoprophylaxis after kidney transplantation is…
2019 American Transplant Congress
Butyrate-Producing Gut Bacteria and Future Development of Viral Infections in Kidney Transplant Recipients
J. Lee¹, J. Huang¹, M. Magruder¹, L. Zhang¹, M. Lubetzky¹, D. Dadhania¹, E. Edusei¹, E. Pamer², M. Suthanthiran¹
¹Weill Cornell Medicine, New York, NY, ²Memorial Sloan Kettering Cancer Center, New York, NY
*Purpose: Recent studies suggest that the gut microbiome plays a critical role in protecting its host from infections beyond Clostridium difficile. Notably, butyrate-producing bacteria may…
2019 American Transplant Congress
Nationwide Survey of Human T Cell Leukemia Virus Type 1-Infected Kidney Transplant Recipients in Japan
J. Yamauchi¹, Y. Yamano¹, M. Matsuoka², N. Ichimaru³, M. Nishikido⁴, Y. Shibagaki⁵, A. Sugitani⁶, N. Nakamura⁷, M. Mieno⁸, K. Yuzawa⁹
¹Department of Rare Diseases Research, Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan, ²Institute for Virus Research, Kyoto University, Kyoto, Japan, ³Advanced Technology for Transplantation, Osaka University, Osaka, Japan, ⁴Blood Purification Center, Nagasaki University, Nagasaki, Japan, ⁵Department of Nephrology and Hypertention, St. Marianna University School of Medicine, Kawasaki, Japan, ⁶NHO Yonago Medical Center, Yonago, Japan, ⁷Fukuoka University, Fukuoka, Japan, ⁸Center for Information, Jichi Medical University, Shimotsuke, Japan, ⁹Department of Transplantation Surgery, National Hospital Organization Mito Medical Center, Ibaraki, Japan
*Purpose: Human T-cell leukemia virus type 1 (HTLV-1) infects 5 to 10 million people worldwide, and is endemic in Japan, sub-Saharan Africa, South America, and…
2019 American Transplant Congress
Outbreak of Pneumocystis Pneumonia in a Transplant Center Linked to a Single Genotype of Pneumocystis jirovecii: Effects of Cytomegalovirus Infection and Allograft Rejection
S. Hosseini-Moghaddam¹, S. Dufresne², M. Shokoohi³, G. Singh¹, E. HunterGutierrez¹, P. Dufresne², A. House¹, P. Luke¹, A. Nagpal¹, P. Marotta¹, A. Humar⁴, A. Jevnikar¹, D. Kumar⁴
¹Western University,LHSC,University Hospital, London, ON, Canada, ²Maisonneuve-Rosemont Hospital,Université de Montréal, Montreal, QC, Canada, ³Epidemiology and Biostatistics, Western University, London, ON, Canada, ⁴University of Toronto, University Health Network, Toronto General Hospital, Toronto, ON, Canada
*Purpose: Although post-transplant pneumocystis pneumonia (PCP) outbreaks have been reported from Asia, Australia and Europe, there are limited data from North America. We investigated transmissibility…
2019 American Transplant Congress
Perceptions and Attitude of Transplant Clinicians towards Antimicrobial Resistance and Stewardship in Transplant Recipients: A Survey of the American Society of Transplantation
M. So¹, J. Hand², M. Richmond¹, A. Morris³, S. Husain¹
¹University Health Network, Toronto, ON, Canada, ²Ochsner Medical Center, New Orleans, LA, ³Sinai Health System, Toronto, ON, Canada
*Purpose: The perceptions and attitude of transplant clinicians towards antimicrobial stewardship (AMS) is unclear. We conducted a survey to better understand their attitude and perceptions…
2019 American Transplant Congress
Epidemiology of Parvovirus B19 and Anemia among Kidney Transplant Recipients
N. Khoury¹, C. Thongprayoon², N. Leeaphorn³, J. Bruminhent⁴, W. Cheungpasitporn⁵
¹Henry Ford Transplant Institute, Detroit, MI, ²Mayo Clinic, Rochester, MN, ³University of Missouri, Kansas City, MO, ⁴Mahidol University, Bangkok, Thailand, ⁵University of Mississippi, Jackson, MS
*Purpose: Persistent anemia has been described in kidney transplant (KTx) recipients with Parvovirus B19 virus infection. However, epidemiology of Parvovirus B19 and Parvovirus B19-related anemia…
2019 American Transplant Congress
Early Diagnosis of BK Virus Nephropathy Can Retrieve Kidney Allografts by Simple Reduction in Immunosuppressive Agents
N. Iwahara, D. Iwami, K. Hotta, H. Okada, N. Shinohara
Hokkaido Univercity, Sapporo, Japan
*Purpose: Although BK virus nephropathy (BKVN) is a major complication after kidney transplant leading to graft loss, it is often difficult to diagnose and treat.…
2019 American Transplant Congress
The Effects of Chronic Kidney Disease on Antiviral T Cell Response
R. L. Crepeau¹, H. Li², L. P. Daley-Bauer³, M. L. Ford¹, P. D. Winterberg²
¹Emory Transplant Center, Atlanta, GA, ²Pediatrics, Emory University School of Medicine, Atlanta, GA, ³Microbiology & Immunology, Emory University School of Medicine, Atlanta, GA
*Purpose: Accumulation of memory T cells bearing markers of sustained antigen stimulation have been described in patients with chronic kidney disease (CKD). Cytomegalovirus (CMV) establishes…
2019 American Transplant Congress
Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection in Solid Organ Transplant Recipients at an Academic Medical Center
J. S. Kerr, N. Law, S. Aslam
Center for Transplantation, University of California, San Diego Health System, La Jolla, CA
*Purpose: In the United States, the incidence of Clostridium difficile infection (CDI) has increased remarkably and remains a significant burden in the solid organ transplant…