Articles tagged "Infection"

2019 American Transplant Congress
Biomarkers in Multivisceral and Intestinal Transplantation
D. A. Cheung¹, J. Garcia¹, T. Beduschi², A. H. Langshaw¹, K. L. Arheart³, I. A. Gonzalez⁴
¹Pediatric Gastroenterology, University of Miami, Miami, FL, ²Surgery, Division of Liver/GI Transplant, University of Miami, Miami, FL, ³Public Health Sciences, Division of Biostatistics, University of Miami, Miami, FL, ⁴Pediatric Infectious Diseases and Immunology, University of Miami, Miami, FL
*Purpose: Multivisceral transplant (MVT) and isolated intestinal transplant (ITx) are complex surgical procedures that result in a pro-inflammatory state, making interpretation of biomarkers in the…
2019 American Transplant Congress
A Comparison of Cell-Mediated Immune Responses among Organ Transplant Recipients Receiving High-Dose vs Standard-Dose Influenza Vaccine
A. G. L'Huillier, V. H. Ferreira, Y. Natori, T. Ku, C. Hirzel, M. Ierullo, A. Humar, D. Kumar
University Health Network, Toronto, ON, Canada
*Purpose: The High-dose (HD) influenza vaccine has been shown to induce better humoral immunity than the standard-dose (SD) vaccine in solid organ transplant (SOT) patients.…
2019 American Transplant Congress
Circulating Exosomes Isolated from Human Lung Transplant Recipients with Respiratory Viral Infections Contain Nucleic Acids Specific to Virus and Can Lead to Activation of Stress Proteins
S. Bansal, R. Bremner, M. Smith, T. Mohanakumar
Norton Thoracic Institute, St. Joseph’s Hospital and Medical Center, Phoenix, AZ
*Purpose: Exosomes are membrane vesicles released by cells into body fluids. Our laboratory demonstrated the presence of circulating exosomes with lung self-antigens (SAgs), Collagen V…
2019 American Transplant Congress
Preventing Donor Derived Cryptococcal Infections: Should We Screen Potential Organ Donors with a Serum Cryptococcal Antigen? A Cost Analysis
C. Santos¹, E. Ritz¹, Y. Rhee¹, I. George², J. Pulvirenti³, N. Moore¹, E. Hollinger¹, L. Proia¹
¹Rush University Medical Center, Chicago, IL, ²Washington University, St. Louis, MO, ³Mercy Hospital, Rockford, IL
*Purpose: Donor-derived cryptococcosis is a rare but deadly infection. Serum cryptococcal antigen testing is a sensitive, specific and inexpensive modality that can be used to…
2019 American Transplant Congress
The Economic Impact of Surgical Site Infections in Liver Transplantation
Y. Natori¹, D. Kumar², A. Humar², S. Husain², C. Rotstein³
¹Miami Transplant Institute, University of Miami, Miami, FL, ²Transplant Infectious Diseases, University of Toronto, Toronto, ON, Canada, ³University of Toronto, Toronto, ON, Canada
*Purpose: Complications arising after liver transplantation result in additional healthcare costs. Previous studies have not evaluated the impact of surgical site infections on healthcare costs…
2019 American Transplant Congress
Approach to Leukopenia in Older Kidney Transplant Recipients
M. Shearer, M. Labonte, L. Erbe, R. Rodgriuez, A. Price, V. Rao, M. Casey, K. Soliman, D. Lazarus, D. Taber, M. Posadas Salas
Dept of Medicine, Medical University of South Carolina, Charleston, SC
*Purpose: Older kidney transplant recipients face challenges of post-transplant complications related to frailty and comorbidity burden. They are particularly vulnerable to side effects of immunosuppression…
2019 American Transplant Congress
Incidence, Risk Factors, Outcomes and Clinical Management of BK Viremia in the Modern Era of Kidney Transplantation
J. Kim
Toronto General Hospital, Toronto, ON, Canada
*Purpose: BK viremia is endemic among kidney transplant recipients (KTR). Previous work has not compared the incidence, risk factors, and outcomes of any vs. clinically…
2019 American Transplant Congress
Human Neutrophil Function against Pathogens in Solid Organ and Stem Cell Transplant Recipients
N. Barros, N. Alexander, Z. Dagher, S. Knooihuizen, A. Viens, A. R. Hopke, D. Irimia, M. K. Mansour
Transplant Infectious Diseases, Massachusetts General Hospital, Boston, MA
*Purpose: The effects of solid organ (SOT) and allogeneic stem cell transplantation (SCT) on the neutrophil function is not well described. In this study, we…
2019 American Transplant Congress
Burden of Respiratory Syncytial Disease among Hospitalized Immunocompromised Adults
H. Nam, M. Ison
Northwestern University Comprehensive Transplant Center, Chicago, IL
*Purpose: Respiratory syncytial virus (RSV) is associated with significant mortality amongst hematopoietic stem cell transplant (HSCT) and lung transplant recipients. Although RSV is responsible for…
2019 American Transplant Congress
Quantifying Differential Infection Risks in HLA- and/or ABO- Incompatible Kidney Transplant Recipients
R. Avery¹, R. Montgomery², J. Motter¹, A. Massie¹, E. Kraus¹, K. Marr¹, B. Lonze², N. Alachkar¹, K. Jackson¹, M. Holechek¹, D. Ostrander¹, N. Desai¹, M. Waldram¹, S. Shoham¹, S. Mehta¹, J. Hiller¹, J. Langlee¹, S. Young¹, D. Segev¹, J. Garonzik Wang¹
¹Johns Hopkins, Baltimore, MD, ²New York University, New York, NY
*Purpose: Desensitization has enabled kidney transplantation across HLA-and/or ABO barriers and has conferred survival benefit to patients who lack compatible living donors (CLDKT). However, due…