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Articles tagged "Infection"

  • 2020 American Transplant Congress

    Artificial Intelligence May Predicts Early Sepsis in Liver Transplantation

    R. D. Kamaleswaran1, R. Lowell Davis2, J. D. Eason3, S. Sataphaty4, V. R. Mas5, D. Maluf3

    1Biostatistics, Emory, Atlanta, GA, 2Center for Biomedical Informatics & Division of Critical Care Medicine, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, 3Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, 4Sandra Atlas Bass Center for Liver Diseases & Transplantation, Northshore University Hospital/Northwell Health, NSHS, NY, 5Biostatistics, Emory, Atlanta, TN

    *Purpose: Sepsis post liver transplantation is a frequent challenge impacting patient outcomes. We aimed to develop an artificial intelligence method to predict earlier the onset…
  • 2020 American Transplant Congress

    Identification of Cell Types That Harbor Cytomegalovirus DNA in Acutely and Latently Infected Mice Spleen

    A. S. Maganti1, X. Liu2, M. Abecassis2

    1Illinois Math and Science Academy, Aurora, IL, 2Comprehensive Transplant Center, Northwestern University, Chicago, IL

    *Purpose: Cytomegalovirus (CMV) is a ubiquitous β‐herpesvirus that infects majority of humans. Primary CMV infection may be asymptomatic or manifests as a self‐limited febrile illness…
  • 2020 American Transplant Congress

    Incidence of Cytomegalovirus and Role of Reduced Dose Valganciclovir in Kidney Transplant Recipients

    A. Szczepanik1, E. Metzker1, C. Burrelli1, K. Chavin2

    1Pharmacy, University Hospitals Cleveland Medical Center, Cleveland, OH, 2Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH

    *Purpose: Valganciclovir (VGC) is the optimal agent for preventing cytomegalovirus (CMV) but its use is limited by cost and leukopenia. Reduced dose VGC (rVGC) has…
  • 2019 American Transplant Congress

    Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection in Solid Organ Transplant Recipients at an Academic Medical Center

    J. S. Kerr, N. Law, S. Aslam

    Center for Transplantation, University of California, San Diego Health System, La Jolla, CA

    *Purpose: In the United States, the incidence of Clostridium difficile infection (CDI) has increased remarkably and remains a significant burden in the solid organ transplant…
  • 2019 American Transplant Congress

    Vaccine Response as a Predictor of Kidney Transplant Rejection and Serious Infection

    A. Ta'eed, K. R. Polkinghorne, W. R. Mulley

    Department of Nephrology, Monash Health, Clayton, Australia

    *Purpose: Vaccination generates immune memory, including antibodies against harmful pathogens. Transplant immunosuppression prevents similar processes occurring against alloantigens. Transplant recipients have significantly reduced seroresponses to…
  • 2019 American Transplant Congress

    Pneumocystis Prophylaxis in Solid Organ Transplant Recipients at Two Large Transplant Centers from 2015-2016: Why Not Trimethoprim-Sulfamethoxazole?

    J. M. Lum1, V. Athans2, I. Echenique3, C. E. Koval1

    1Infectious Diseases, Cleveland Clinic Floundation, Cleveland, OH, 2Infectious Diseases, University of Pennsylvania, Philadelphia, PA, 3Infectious Diseases, Cleveland Clinic Florida, Weston, FL

    *Purpose: Trimethoprim-sulfamethoxazole (T/S) is the drug of choice for Pneumocystis jirovecii pneumonia (PJP) prophylaxis (ppx) after solid organ transplant (SOT). Perceived side effects may lead…
  • 2019 American Transplant Congress

    Higher Post-Transplant CXCL13 Correlates with the Occurrence of Infection within 1 Year after Kidney Transplantation

    Y. Li1, Y. Li1, L. Yan1, L. Wang1, Y. Shi2, J. Tang1

    1Department of Laboratory Medicine/Research Centre of Clinical Laboratory Medicine, West China Hospital, Chengdu, China, 2Department of Nephrology, West China Hospital, Chengdu, China

    *Purpose: Chemokine is a subtype of cytokines that involved in the process of inflammation and immune responses, and play an important role in both kidney…
  • 2019 American Transplant Congress

    Donor-Derived Carbapenem-Resistant Klebsiella Pneumoniae Infection after Renal Transplantation

    B. Liu, M. Wang, F. Zeng, S. Chang, N. Gong, G. Chen, Z. Chen

    Institute of Transplantation, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China

    *Purpose: We summarized the experience of diagnosis and treatment of donor-derived carbapene-resistant klebsiella pneumoniae (CRKP) infection after renal transplantation.*Methods: From January 2015 to June 2018,…
  • 2019 American Transplant Congress

    Impact of Enteric Vancomycin Resistant Enterococcus Colonization on Waitlist Outcomes among Liver Transplant Candidates

    E. Aldag, R. Pedersen, V. Gunabushanam, A. Sahajpal, T. J. Dilworth

    Aurora St Luke's Medical Center, Milwaukee, WI

    *Purpose: To determine the impact of Vancomycin Resistant Enterococcus (VRE) colonization on 90-day Liver Transplant (LT) waitlist outcomes.*Methods: Single center, retrospective observational study of LT…
  • 2019 American Transplant Congress

    Routine Molecular Clostridioides difficile Screening and Overtreatment in Solid Organ Transplant Recipients

    M. E. Newman1, C. Oehler1, M. Enriquez1, E. Landon1, C. T. Nguyen2, N. N. Pettit2, J. P. Ridgway1, J. Pisano1

    1Section of Infectious Disease, University of Chicago Medicine, Chicago, IL, 2Department of Pharmacy, University of Chicago Medicine, Chicago, IL

    *Purpose: The objective of this analysis is to determine how frequently positive Clostridioides difficile (CD) screening tests, potentially identifying up to 20% of inpatients with…
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