Articles tagged "Infection"

2020 American Transplant Congress
Successful Use of Tedizolid for the Treatment of Nocardiosis in Transplant Recipients
R. Odrobina¹, B. Tritle², C. A.Gomez¹
¹Division of Infectious Diseases, University of Utah, Salt Lake City, UT, ²Department of Pharmacy, University of Utah, Salt Lake City, UT
*Purpose: Nocardiosis is an opportunistic infection occasionally seen after solid organ (SOT) and hematopoietic stem-cell transplantation. Treatment is challenging due to the limited number of…
2020 American Transplant Congress
Chronic Kidney Disease Alters the T Cell Response to Murine Cytomegalovirus
R. L. Crepeau¹, H. Li¹, H. S. Koehler², M. L. Ford¹, P. D. Winterberg³
¹Surgery, Emory University, Atlanta, GA, ²Microbiology and Immunology, Emory University, Atlanta, GA, ³Pediatrics, Emory University, Atlanta, GA
*Purpose: We have previously reported that patients with chronic kidney disease (CKD) accumulate memory T cells bearing markers of sustained antigen stimulation and enhanced pro-inflammatory…
2020 American Transplant Congress
Infectious Complications and Malignancy after Kidney Transplantation in the Elderly Population
L. Liriano-Ward, M. Parides, Y. Al Azzi, C. Pynadath, M. Ajaimy, J. Graham, S. Greenstein, M. Kinkhabwala, J. Rocca, E. Akalin
Montefiore Medical Center, Bronx, NY
*Purpose: Kidney transplantation improves quality of life and survival in all patients regardless of age. However, older patients are prone to development of side effects…
2020 American Transplant Congress
Safety Outcomes in Lower-Weight vs Higher-Weight Recipients of Fixed Dose Alemtuzumab for Kidney Transplant Induction
A. Freeman, S. Anders, B. Wise, M. Janusek, L. Hutchinson, U. Kaszubski, D. Marroquin, D. Martin, H. Bohorquez
Ochsner Medical Center, New Orleans, LA
*Purpose: Alemtuzumab is a lymphocyte-depleting monoclonal antibody used for renal transplant induction, and is associated with significant leukopenia, increased infections and malignancy. Multiple dosing strategies…
2020 American Transplant Congress
High Rate of Positive Cultures from Deceased Donors, A Review of 500 Deceased Donors and More Than 700 Recipients from a Single Center in Saudi Arabia
R. S. Almaghrabi¹, R. Alameer¹, O. Zeitoni², M. Ahmed³, I. Nizami³, J. Alburaiki⁴, T. Aljurf¹, R. Alyamany¹, A. Abed², D. Broering³
¹Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia, ²Alfaisal University, Riyadh, Saudi Arabia, ³Organ Transplant Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia, ⁴Heart Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
*Purpose: Limited organ supply is one of the major challenges facing organ transplantation. Donor-derived multidrug-resistant (MDR) bacteria have been documented with variable outcomes. In Saudi…
2020 American Transplant Congress
Significance of Gene Polymorphism on Infectious Complications and Rejection after Liver Transplantation
H. Egawa¹, T. Kato¹, Y. Kotera¹, A. Ohmori¹, G. Shibuya¹, S. Yamashita¹, S. Ariizumi¹, M. Yamamoto¹, T. Ishizuka², Y. Tanaka³, H. Ohdan³
¹Tokyo Women's Medical University, Tokyo, Japan, ²Clinical Labotratory, Tokyo Women's Medical University, Tokyo, Japan, ³Surgery, Hiroshima University, Hiroshima, Japan
*Purpose: Clinical application of gene polymorphism is a key of precision medicine in the field of organ transplantation. Infection and rejection are major factors affecting…
2020 American Transplant Congress
Vira-ome: A Tool for an Unbiased Plasma Virome Analysis of SOT Recipients from Cell-Free DNA Sequences
R. Sinha, E. Bixler, J. Grantham, M. Altrich, S. Kleiboeker
R&D, Viracor-Eurofins, Lee's Summit, MO
*Purpose: Blood virome of healthy individuals is frequently predominated by member of families such as Herpesvirus, Anellovirus and Polyomaviridae. The viral load of commensal species…
2020 American Transplant Congress
Antimicrobial Prophylaxis Post Antibody Mediated Rejection Treatment in Pediatric Kidney Transplant Recipients: Interim Report from the Paramour “PediAtric Renal AMr Outcomes” Study
S. Solomon¹, R. Garro², N. Hayde³, A. Jain⁴, M. Kallash⁵, K. Twombley⁶, I. Ashoor⁷
¹Maria Fareri Children's Hospital, Valhalla, NY, ²Emory University, Atlanta, GA, ³The Children's Hospital at Montefiore, Bronx, NY, ⁴Children's Hospital of Michigan, Detroit, MI, ⁵Nationwide Children's Hospital, Columbus, OH, ⁶Medical University of South Carolina, Charleston, SC, ⁷LSU Health New Orleans, New Orleans, LA
*Purpose: Universal guidelines do not exist for post antibody mediated rejection (AMR) treatment antimicrobial prophylaxis (ppx) in pediatric kidney transplant (KT) recipients. We sought to…
2020 American Transplant Congress
Teduglutide Therapy in Real World Setting is Efficacious in Reducing Complications in Short Bowel Syndrome
T. Ashraf¹, V. Mendiratta², M. Abu Ghanimeh², H. Abdulla¹, S. Nagai³, N. Beltran³, S. Jafri²
¹Internal Medicine, Henry Ford Hospital, Detroit, MI, ²Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI, ³Transplant Surgery, Henry Ford Hospital, Detroit, MI
*Purpose: Teduglutide, a GLP-2 analogue, increases portal and intestinal blood flow thereby increasing absorption of fluid and nutrients. We evaluated outcomes of Teduglutide therapy for…
2020 American Transplant Congress
Efficacy of Single-Strength Trimethoprim-Sulfamethoxazole Thrice Weekly for Pneumocysitis Jirovecii Pneumonia Prophylaxis Post Liver Transplantation
A. Puing, A. Subramanian
Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA
*Purpose: Current guidelines recommend Pneumocystis jirovecii pneumonia (PJP) prophylaxis for at least 6-12 months after liver transplant (LTx) with preferably Trimethoprim-sulfamethoxazole (TMP-SMX) at a daily…