Articles tagged "Infection"

2021 American Transplant Congress
Clinical Signs Predictive of Covid-19 Mortality Among Transplant Recipients
D. Ginzberg¹, K. Pierce², E. Kreiger-Benson², M. Graves², H. Neumann³, N. Ali³, C. Gidea³, J. Park³, S. Mehta³
¹Hackensack University Medical Center, Hackensack, NJ, ²New York University Grossman School of Medicine, New York, NY, ³New York University Langone Transplant Institute, New York, NY
*Purpose: The presentation of Coronavirus disease 2019 (COVID-19) ranges from mild illness to severe respiratory failure. Disease progression may differ in immunocompromised patients and immunocompetent…
2021 American Transplant Congress
Covid-19 in Hiv-infected Solid Organ Transplant Recipients: A Case Series
M. Ramanathan, A. Fernandez, Y. Natori, J. Simkins, J. Camargo, M. Morris, N. Rivera, M. Loebe, G. Ciancio, L. Abbo, A. Mattiazzi, G. Guerra, S. Anjan
University of Miami, Miami, FL
*Purpose: Coronavirus disease 2019 (COVID-19) is associated with increased mortality and morbidity in immunosuppressed patients. Data on management and outcomes in HIV-infected solid organ transplant…
2021 American Transplant Congress
Outcomes of Kidney Transplantation at the Epicenter of the Covid-19 Pandemic: The Experience of the Ospedale Maggiore Policlinico
E. Favi¹, C. Alfieri², M. Gandolfo², A. Brescacin¹, M. Bilato³, R. Cacciola⁴, P. Messa², M. Ferraresso⁵
¹Renal Transplantation, Ospedale Maggiore Policlinico, Milan, Italy, ²Nephrology, Ospedale Maggiore Policlinico, Milan, Italy, ³Urology, Ospedale Maggiore Policlinico, Milan, Italy, ⁴HBP Surgery, Policlinico Tor Vergata, Rome, Italy, ⁵Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
*Purpose: To evaluate patient- and allograft-related outcomes following living and deceased donor kidney transplantation (KTx) in a unit operating at the epicentrum of the COVID-19…
2021 American Transplant Congress
Influence of HLA Compatibility on Bk Virus Associated Nephropathy Among Japanese Living Donor Kidney Transplant Recipients
N. Fujiyama¹, M. Saito², R. Yamamoto², R. Sagehashi², T. Saito², S. Kashima², K. Numakura², S. Narita², T. Habuchi², S. Satoh¹
¹Center for Kidney Disease and Transplantaion, Akita University Hospital, Akita, Japan, ²Department of Urology, Akita University Graduate School of Medicine, Akita, Japan
*Purpose: BK polyomavirus-associated nephropathy (BKVN) after kidney transplantation is associated with a high morbidity and higher risk of graft loss. In this study, the relationship…
2021 American Transplant Congress
Impact of Positive Donor Cultures on Postoperative Lung Transplantation Infectious Outcomes
A. Curtis, C. Pham, B. P. Pierce
Houston Methodist Hospital, Houston, TX
*Purpose: Transmission risk of microbes present in donor lungs at time of donation to lung transplant recipients (LTR) is unclear. Infection is the second highest…
2021 American Transplant Congress
High Levels of Sars-cov-2 Detected in Immunosuppressed Covid-19 Patient Environments Weeks Following Initial Positive Test
C. E. Kuschner¹, Z. Brune², L. B. Becker¹, L. Teperman¹
¹North Shore University Hospital, Manhasset, NY, ²Feinstein Institutes for Medical Research, Manhasset, NY
*Purpose: COVID-19 is a novel viral illness associated with significantly worse mortality, prolonged disease course, and extended periods of viral shedding in transplant patients on…
2021 American Transplant Congress
T-cell-Mediated Immunity to Sars-cov-2 Defines Covid-19 Risk and Severity in Transplanted and Non-Transplanted Individuals and Associates with Myeloid-Derived Suppressor Cells
C. Ashokkumar¹, V. Rohan², A. H. Kroemer³, S. Rao⁴, G. Mazariegos⁵, B. W. Higgs⁵, S. Nadig², M. Ningappa⁵, T. Fishbein³, S. Subramaniam⁶, R. Sindhi⁷
¹Plexision, Pittsburgh, PA, ²Medical University of South Carolina, Charleston, SC, ³MedStar Georgetown Transplant Institute, Georgetown, DC, ⁴DHR Health Institute for Research and Development, Texas, TX, ⁵University of Pittsburgh, Pittsburgh, PA, ⁶University of California, San Diego, CA, ⁷University of Pittsburgh, pittsburgh, PA
*Purpose: We assessed whether COVID-19-risk is enhanced by chronic immunosuppression, and is associated with suppressor cells.*Methods: We tested 66 COVID-19 patients, including 26 with solid…
2021 American Transplant Congress
Covid-19 in Solid Organ Transplantation (SOT): Results of the National Covid Cohort Collaborative (N3C)
G. Agarwal¹, A. Vinson², R. Dai³, E. French⁴, S. Lee⁵, A. Olex⁴, A. Anzalone⁶, V. Madhira⁷, R. B. Mannon⁸
¹Medicine, University of Alabama at Birmingham, Birmingham, AL, ²Medicine/Nephrology, Nova Scotia Health Authority, Halifax, NS, Canada, ³Biostatistics, University of Nebraska Medical Center, Omaha, NE, ⁴Wright Center for Clinical and Translational Research, VIrginia Commonwealth University, Richmond, VA, ⁵Medicine/Infectious Disease, University of Saskatchewan, Saskatoon, SK, Canada, ⁶Neurology, University of Nebraska Medical Center, Omaha, NE, ⁷Palia Software, Not sure, OR, ⁸Medicine/Nephrology, University of Nebraska Medical Center, Omaha, NE
*Purpose: SARS-CoV-2 infection has resulted in significant mortality in solid organ transplant (SOT) recipients based on reports from single centers or voluntary registries. The N3C…
2021 American Transplant Congress
Should We Worry About Covid-19 Infection in Pediatric SOT?
U. Ekong¹, S. Paul¹, S. Royal², J. Chahine³, N. Yazigi¹, S. Kaufman¹, K. Khan¹, C. Matsumoto¹, A. Kroemer¹, T. Fishbein¹
¹Surgery, Medstar Georgetown Transplant Institute, Washington, DC, ²Pediatrics, Medstar Georgetown University Hospital, Washington, DC, ³Pathology and Laboratory Medicine, Medstar Georgetown University Hospital, Washington, DC
*Purpose: We describe the clinical presentation & immune response to COVID-19 infection in pediatric SOT.*Methods: Medical records of COVID-19 PCR+ or seropositive patients were reviewed…
2021 American Transplant Congress
Observational Study of the Clinical Characteristics and Short-term Outcomes of Kidney Transplant Recipients Diagnosed with Coronavirus-19 Infection (sars-cov2) Requiring Hospitalization in New Orleans
S. Giusti¹, S. Chazin², P. Vaitla³, K. Atiemo⁴, M. Atari¹, A. Paramesh⁴, H. Jeon⁴, A. Vijay⁴, A. Torres⁵, M. Killackey⁴, R. Thimmisetty⁶, J. Garces⁶
¹Tulane University Section of Nephrology & Hypertension, New Orleans, LA, ²Tulane University School of Medicine, New Orleans, LA, ³University of Mississippi Medical Center, Jackson, MS, ⁴Tulane Transplant Institute, New Orleans, LA, ⁵Ochsner Medical Center, New Orleans, LA, ⁶Ochsner Multi-Organ Transplant Institute, New Orleans, LA
*Purpose: Kidney transplant recipients are at increased risk of severe disease and death caused by Coronavirus-19 infection. The role of immunosuppressive medications in the clinical…