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Articles tagged "Infection"

  • 2022 American Transplant Congress

    Plasma Galectin-3 is Predictive of Post-Transplant Infection in Pediatric Liver Transplant Recipients

    D. Yoeli, A. Chaidez, Y. Luo, J. Huang, N. Limon De La Rosa, N. Nakra, Z. Wang, E. Cervantes-Alvarez, M. Adams, C. Mack, C. Huang, N. Navarro-Alvarez

    University of Colorado Anschutz Medical, Aurora, CO

    *Purpose: Galectin-3 (Gal3) is a beta-galactoside binding lectin that plays a key role in inflammation and immune response. Infectious complications are common among pediatric liver…
  • 2022 American Transplant Congress

    Organs from Donors with Positive SARS-CoV-2 NAT+ Testing: A Report from the Ad Hoc Disease Transmission Advisory Committee

    L. Danziger-Isakov1, J. D. Goldman1, A. Wooley1, S. Pouch1, A. Agarwal1, G. Berry1, K. Dunn1, S. Ho1, M. Kittleson1, D. H. Lee1, D. Levine1, C. Marboe1, G. Marklin1, R. Razonable1, S. Taimur1, H. Te1, C. Fox2, C. Jett2, S. Booker2, D. Klassen2, R. LaHoz1

    1OPTN, Richmond, VA, 2UNOS, Richmond, VA

    *Purpose: Decision to transplant organs from SARS-CoV-2 NAT+ donors(N+D) balances risk of donor-derived infection with the scarcity of available organs to meet the needs of…
  • 2022 American Transplant Congress

    HLA Alleles Add to Risk Stratification for CMV Infection in Renal Transplant Recipients

    R. Patil1, R. Prashar2, M. Ramesh2, A. Patel2

    1Wayne State University School of Medicine, Detroit, MI, 2Henry Ford Transplant Institute, Detroit, MI

    *Purpose: Cytomegalovirus (CMV) is the most common viral infection that occurs after solid organ transplantation. The incidence of CMV infection or disease (I/d) varies based…
  • 2022 American Transplant Congress

    Early versus Delayed Cytomegalovirus Prophylaxis in High-Risk Kidney Transplant Recipients

    A. Hutchins1, M. Leick2, M. Keck2, J. S. McMullen2

    1Pharmacy, Houston Methodist Hospital, Houston, TX, 2Pharmacy, Nebraska Medicine, Omaha, NE

    *Purpose: The purpose of this study is to determine the effect of delaying cytomegalovirus (CMV) prophylaxis to day of discharge or post-operative day (POD) 7…
  • 2022 American Transplant Congress

    Lung Transplantation Outcomes in Recipients Living with HIV in the United States

    J. M. Czeresnia1, S. Madan2, M. M. Abbasi3, V. Hemmige1

    1Department of Medicine - Division of Infectious Diseases, Montefiore Medical Center, Bronx, NY, 2Department of Medicine - Division of Cardiology, Montefiore Medical Center, Bronx, NY, 3Department of Surgery - Division of Cardiovascular and Thoracic Surgery, Montefiore Medical Center, Bronx, NY

    *Purpose: To compare outcomes of lung transplantation in HIV-positive and HIV-negative recipients in the United States.*Methods: A national transplant database (UNOS/SRTR) was queried for cases…
  • 2022 American Transplant Congress

    Data-Driven Clustering Distinguishes Infection from Rejection During Hospital Admissions Following Pediatric Lung Transplantation

    C. D. Britto1, D. Boyer2, G. Visner3, G. Priebe4, L. Midyat3

    1Department of Pediatrics, Boston Children's Hospital, Boston, MA, 2Division of Pulmonary Medicine, Nationwide Children's Hospital, Ohio, MA, 3Division of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, 4Department of Anesthesiology, Critical Care and Pain Medicine, Division of Infectious Disease, Boston Children's Hospital, Boston, MA

    *Purpose: When lung transplantation patients are admitted with respiratory symptoms, distinguishing between episodes of infection and rejection is central to determining immunosuppressive management.*Methods: Data comprising…
  • 2022 American Transplant Congress

    Implementation of Infectious Disease Surveillance in Recently Deceased Human Xenograft Study

    S. J. Cawthon, E. P. Weldon, N. S. Lawson, B. E. Lonze, R. A. Montgomery, S. A. Mehta

    NYU Langone Transplant Institute, New York, NY

    *Purpose: Xenotransplantation is a promising solution for the ongoing organ shortage but has been slow to develop because of both immunological challenges and potential risk…
  • 2022 American Transplant Congress

    The Role of Gastrointestinal Pathogen PCR Testing in Liver Transplant Recipients Hospitalized with Diarrheal Illness

    C. K. Ching1, Y. R. Nobel2, M. R. Pereira3, E. C. Verna4

    1Department of Medicine, Columbia University Medical Center, New York, NY, 2Division of Digestive and Liver Diseases, Columbia University Medical Center, New York, NY, 3Division of Infectious Diseases, Columbia University Medical Center, New York, NY, 4Center for Liver Disease and Transplantation, Columbia University Medical Center, New York, NY

    *Purpose: Diarrhea is a common complication among liver transplant (LT) recipients and can result in significant morbidity. The development of PCR-based multiplex gastrointestinal (GI) pathogen…
  • 2022 American Transplant Congress

    Impact of Target Tacrolimus Levels on BK Polyomavirus DNAemia and Allograft Rejection Among Pediatric Kidney Transplant Recipients

    H. Huang1, P. Winterberg1, R. George1, A. Serluco2, R. Liverman2, I. Yildirim3, R. Garro1

    1Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, 2Children's Healthcare of Atlanta, Atlanta, GA, 3Yale University School of Medicine, New Haven, CT

    *Purpose: BK Polyomavirus (BK) DNAemia is a serious and common infectious complication after kidney transplant (KT). We evaluated the impact of targeting lower tacrolimus levels…
  • 2022 American Transplant Congress

    Prevalence and Characteristics of Covid-19-Associated Pulmonary Diagnoses in Lung Transplant Patients in the United States

    T. G. Mupfudze1, A. R. Wilk1, R. R. Goff1, M. Valapour2, J. Miller3, M. Budev2, E. D. Lease4

    1Research Department, United Network for Organ Sharing, Richmond, VA, 2Respiratory Institute, Cleveland Clinic, Cleveland, OH, 3Scientific Registry of Transplant Recipients, Minneapolis, MN, 4Division of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Seattle, WA

    *Purpose: Lung transplant may be a viable treatment option for select patients with non-recoverable COVID-19-associated acute respiratory distress syndrome (ARDS) and COVID-19-associated pulmonary fibrosis. This…
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