Articles tagged "Infection"

2021 American Transplant Congress
Characterization of Retransplantation Following Graft Failure Due to Bkvn
K. Nguyen¹, H. Curtis², J. Panichella², H. Resweber³, A. Di Carlo², S. Karhadkar¹
¹Surgery, Temple University School of Medicine, Philadelphia, PA, ²Surgery, Temple University School of Medicine, Philadephia, PA, ³Surgery, Temple University School of Medicine, Gladwyne, PA
*Purpose: Immunosuppression following kidney transplantation allows for the reactivation of BK polyomavirus (BKV)- frequently implicated in graft dysfunction and failure. Although BKV Nephropathy (BKVN) was…
2021 American Transplant Congress
Clinical Consequences in Patients Experiencing Leukopenia and Neutropenia After Solid Organ Transplant
A. Diamond¹, N. Diehl², K. Hiryak³, K. Mortia¹, J. Au¹, C. Ruggia-Check¹, H. Clauss⁴
¹Pharmacy, Temple University Hospital, Philadelphia, PA, ²Pharmacy, UPMC Pinnacle Health, Harrisburg, PA, ³Pharmacy, Temple University School of Pharmacy, Philadelphia, PA, ⁴Infectious Diseases, Temple University Hospital, Philadelphia, PA
*Purpose: The incidence of leukopenia and neutropenia in solid organ transplant (SOT) recipients can be influenced by medications required after transplant for immunosuppression and infection…
2021 American Transplant Congress
Weathering the Cytokine Storm: Therapeutic Plasma Exchange for the Management of Severe Covid19 in Solid Organ Transplant Recipients
A. Mattiazzi¹, J. Pagan¹, L. A. Mendez Castaner², A. Fernandez¹, R. Zamora Gonzalez¹, J. Simkins¹, L. Preczewski¹, Y. Natori¹, S. Anjan¹, G. Guerra¹
¹Miami Transplant Institute, Miami, FL, ²Miami Trasnplant Institute, Miami, FL
*Purpose: The treatment of SARS-CoV-2 associated pneumonia in solid organ transplant recipients (SOTr) continues to be under investigation. Timely control of the cytokine release storm…
2021 American Transplant Congress
Risk Factors of COVID-19 in Kidney Transplant Recipients
M. M. Alkadi, E. Abuhelaiqa, M. Asim, O. Fituri, R. Elidrisi, R. Abdul Rahiman, M. Elshirbeny, M. Othman, A. Hamad, A. Ashour, A. Hamdi, A. Nauman, H. Tohid, M. Jarman, H. Al-Malki
Nephrology-Medicine, Hamad Medical Corporation, Doha, Qatar
*Purpose: Kidney transplant recipients have been shown to develop a severe form of coronavirus disease (COVID-19) that poses a significant mortality risk. The aim of…
2021 American Transplant Congress
Incidence of Oral Candidiasis in Renal and/or Pancreas Transplant Recipients When Administering Prophylaxis versus No Prophylaxis
L. Von Stein¹, S. Patel¹, L. Wardlow²
¹Transplant, The Ohio State Wexner Medical Center, Columbus, OH, ²Pharmacy, The Ohio State Wexner Medical Center, Columbus, OH
*Purpose: Oropharyngeal candidiasis (OC), or thrush, is a fungal infection associated with immunosuppression post renal and or/pancreas transplant. Currently, the role of prophylactic oral nystatin…
2021 American Transplant Congress
Single Center Experience on SARS-CoV-2 Testing of Symptomatic and Asymptomatic Pediatric Kidney Transplant Recipients
H. Pizzo¹, P. R. Soni², S. Nadipuram², J. Garrison¹, D. Puliyanda¹
¹Pediatric Nephrology, Cedars-Sinai Medical Center, Los Angeles, CA, ²Pediatric Infectious Disease, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: As of late November 2020, there have been 61.5 million cases of SARS-CoV-2 (COVID-19) worldwide resulting in 1.44 million deaths. Despite the outstanding number…
2021 American Transplant Congress
Letermovir Prophylaxis in Solid Organ Transplant – CMV Breakthrough and Tacrolimus Drug Interaction
R. Winstead¹, D. Kumar¹, A. Brown¹, I. Yakubu¹, C. Song¹, L. Thacker², G. Gupta¹
¹Virginia Commonwealth University Health, Richmond, VA, ²Virginia Commonwealth University, Richmond, VA
*Purpose: Valganciclovir is the preferred drug for cytomegalovirus (CMV) prophylaxis in solid organ transplantation. A limitation to its use is profound myelosuppression. Letermovir is a…
2021 American Transplant Congress
The Impact of Covid-19 Pandemic on Living Donor Liver and Renal Transplantations in Japan: A Nationwide Survey
S. Yamanaga¹, T. Hibi², R. Osawa³, K. Yuzawa⁴, H. Egawa⁵, K. Kuramitsu⁶
¹General Surgery, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan, ²Pediatric Surgery and Transplantation, Kumamoto University, Kumamoto, Japan, ³Infectious disease, Kameda medical center, Kamogawa, Japan, ⁴Transplant Surgery, Mito Medical Center, Higashiibaraki District, Japan, ⁵Gastrointestinal Surgery, Tokyo Women's Medical University Hospital, Shinjyuku-ku, Japan, ⁶HBP surgery, Kobe University, Kobe, Japan
*Purpose: COVID-19 brought a huge impact on the field of organ transplantation. On 6th March, the Japan Society for Transplantation (JST) COVID-19 task force published…
2021 American Transplant Congress
Transcriptomics and Proteomics Profiling of Complement Pathway (cp) Proteins in Biopsies With Polyomavirus Bk Nephropathy (bkvn)
P. Randhawa¹, F. Fei², Y. Huang¹, G. Tseng³, K. Xiao⁴
¹Departments of Pathology, Pittsburgh, PA, ²Pharmacology and Chemical Biology, Pittsburgh, PA, ³Biostatistics, Pittsburgh, PA, ⁴Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA
*Purpose: Late stage BKVN can show C4d as well as classic immune complex deposits in the tubular basement membranes (Bracamonte et al. Am J Transplant…
2021 American Transplant Congress
Influence of Immunosuppressant Management on Mortality in Kidney Transplant Recipients Hospitalized with COVID-19
Y. Fenig, A. Santeusanio, M. Menon, C. Liu, M. Rana, R. Shapiro
Mount Sinai Hospital, New York, NY
*Purpose: Kidney transplant recipients are thought to be at high risk for mortality from COVID-19 due to the necessity for chronic immunosuppressive therapy to prevent…